PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016510625.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family ARR-B
Protein Properties Length: 505aa    MW: 56543.9 Da    PI: 6.834
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016510625.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like81.97.1e-26190243155
         G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                     k+r+ W+ eLHe+F++av+qL G ++A+Pk+ilelm+v+ L +ehv+SHLQkYRl
  XP_016510625.1 190 KARVLWSAELHEKFLQAVNQL-GMDRAVPKKILELMNVPWLKREHVASHLQKYRL 243
                     689******************.********************************7 PP
2Response_reg81.62.4e-27111191109
                     EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTT CS
    Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaG 93 
                     +l+vdD+p+ +++l+++l+k +y ev+++  +e al ll+e++  ++l++ D+ mp+mdG++ll++i  e  +lp+i+++a ++++ + + +  G
  XP_016510625.1  11 LLVVDDDPTCLKILENMLKKCHY-EVTTCNRAEVALSLLRENKneFHLVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDSKNVVMKGVIHG 103
                     599********************.***************888889**********************6654.8********************** PP

                     ESEEEESS--HHHHHH CS
    Response_reg  94 akdflsKpfdpeelvk 109
                     a+d+l Kp+ +e+l +
  XP_016510625.1 104 AHDYLIKPVRIEALKN 119
                     ************9986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF521721.2E-347127IPR011006CheY-like superfamily
Gene3DG3DSA:3.40.50.23005.0E-418132No hitNo description
SMARTSM004488.2E-319121IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.87610125IPR001789Signal transduction response regulator, receiver domain
CDDcd001563.72E-2912124No hitNo description
PfamPF000723.4E-2412119IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS512949.13187246IPR017930Myb domain
SuperFamilySSF466892.33E-18188247IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.608.4E-27189247IPR009057Homeodomain-like
TIGRFAMsTIGR015578.6E-23190243IPR006447Myb domain, plants
PfamPF002495.0E-8194242IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 505 aa     Download sequence    Send to blast
MSSIKFPTLR LLVVDDDPTC LKILENMLKK CHYEVTTCNR AEVALSLLRE NKNEFHLVIS  60
DVHMPDMDGF KLLEHIGLEM DLPVIMMSAD DSKNVVMKGV IHGAHDYLIK PVRIEALKNI  120
WQHVVRKNKD EWKGKVFDQS ESVEDGEWPQ EPPEDVEHSS SANEGNLKRS KKRKEEDETE  180
ERDDMVALKK ARVLWSAELH EKFLQAVNQL GMDRAVPKKI LELMNVPWLK REHVASHLQK  240
YRLLLKKSMG VPQHPSGLNY SFIGHSEATF GTPLNGQLPA QSLATLWGAA LGQSATKSSL  300
HVPLVDQGNH FSFENPKLRF QTQQQLNNSN KQVNLLYGIP TTVEPKQSLR NGIVDNARGD  360
IYNQASQAYS AVDFSLNQNM QLRGSSFPAS GNSAMSTLAT KGMLKEEVNT DIRGSRGFSP  420
NDDSFSGLYQ QTKQDWCLQN VGSTFDTSYH SSIQHRISSM DKSGQNTNAP IAEAVLSSGQ  480
ETGHVNLMGG SQLNSLLEAT KHWNS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A1e-19187247262ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016510625.10.0PREDICTED: two-component response regulator ARR2-like isoform X3
SwissprotQ9ZWJ91e-131ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A1S4DAZ90.0A0A1S4DAZ9_TOBAC; Two-component response regulator
STRINGXP_009767630.10.0(Nicotiana sylvestris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-123response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]