PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016509793.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family MYB
Protein Properties Length: 265aa    MW: 30478.5 Da    PI: 8.2117
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016509793.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding59.95.6e-192471148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     rg+WT eEd llv+++ q+G g+W+  a++ g++Rt+k+c++rw++yl
   XP_016509793.1 24 RGPWTVEEDSLLVNYISQHGEGRWNMLAHRAGLKRTGKSCRLRWLNYL 71
                     89********************************************97 PP
2Myb_DNA-binding51.62.2e-1677120146
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                      rg+ T++E++l+++++ +lG++ W++Ia++++ gRt++++k++w++
   XP_016509793.1  77 RGNLTPQEQLLILELHFKLGNR-WSKIAQYLP-GRTDNEIKNYWRT 120
                      7999******************.*********.***********96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129417.7171971IPR017930Myb domain
SuperFamilySSF466892.24E-3121118IPR009057Homeodomain-like
SMARTSM007175.7E-162373IPR001005SANT/Myb domain
PfamPF002491.6E-162471IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.4E-232578IPR009057Homeodomain-like
CDDcd001671.84E-122671No hitNo description
PROSITE profilePS5129423.98872126IPR017930Myb domain
SMARTSM007171.5E-1476124IPR001005SANT/Myb domain
PfamPF002492.5E-1577120IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.9E-2379125IPR009057Homeodomain-like
CDDcd001673.80E-1181120No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 265 aa     Download sequence    Send to blast
METDMSFLSK SSSSSSDEEI GLRRGPWTVE EDSLLVNYIS QHGEGRWNML AHRAGLKRTG  60
KSCRLRWLNY LKPDVKRGNL TPQEQLLILE LHFKLGNRWS KIAQYLPGRT DNEIKNYWRT  120
RVQKQAKHLK IDSNSAAFQH MIRCIWIPRL LQKIQEITQT PQVLSLERNS ISSSRCCSSR  180
SPSSESMSIY KSPNIISECP KIPPREMGDS VVNVHFPFDD NSYDMDTFSP ATGNFLTNYD  240
QMVGGENNMM NGDILADSFW SMDQF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A2e-27221265108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in abiotic stress responses. Plays a regulatory role in tolerance to salt, cold, and drought stresses. Regulates positively the expression of genes involved in proline synthesis and transport, and genes involved in reactive oxygen species (ROS) scavenging such as peroxidase, superoxide dismutase and catalase during salt stress. Transactivates stress-related genes, including LEA3, RAB16A and DREB2A during salt stress. {ECO:0000269|PubMed:22301384}.
UniProtTranscription repressor of phosphate (Pi) starvation-induced genes. Regulates negatively Pi starvation responses via the repression of gibberellic acid (GA) biosynthesis and signaling. Modulates root architecture, phosphatase activity, and Pi uptake and accumulation. {ECO:0000269|PubMed:19529828}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by salt, cold and osmotic stresses, and abscisic acid (ABA). Down-regulated by salicylic acid (SA). {ECO:0000269|PubMed:22301384}.
UniProtINDUCTION: Slightly induced by salicylic acid (PubMed:16463103). Induced reversibly in response to phosphate (Pi) deficiency but repressed in the presence of Pi, specifically in the leaves. Availability of Pi increases with decreased levels (PubMed:19529828). {ECO:0000269|PubMed:16463103, ECO:0000269|PubMed:19529828}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAJ5389491e-108AJ538949.1 Nicotiana tabacum cDNA-AFLP-fragment BT3-M23-017.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016509793.10.0PREDICTED: transcription factor MYB108-like isoform X3
SwissprotQ10MB45e-74MYB2_ORYSJ; Transcription factor MYB2
SwissprotQ9C9G72e-74MYB62_ARATH; Transcription factor MYB62
TrEMBLA0A1S4D8U10.0A0A1S4D8U1_TOBAC; transcription factor MYB108-like isoform X3
STRINGXP_009804370.11e-170(Nicotiana sylvestris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G68320.14e-75myb domain protein 62
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Yang A,Dai X,Zhang WH
    A R2R3-type MYB gene, OsMYB2, is involved in salt, cold, and dehydration tolerance in rice.
    J. Exp. Bot., 2012. 63(7): p. 2541-56
    [PMID:22301384]
  4. Chen X, et al.
    The NAC family transcription factor OsNAP confers abiotic stress response through the ABA pathway.
    Plant Cell Physiol., 2014. 55(3): p. 604-19
    [PMID:24399239]
  5. Lv Y, et al.
    New insights into the genetic basis of natural chilling and cold shock tolerance in rice by genome-wide association analysis.
    Plant Cell Environ., 2016. 39(3): p. 556-70
    [PMID:26381647]
  6. Hong Y,Zhang H,Huang L,Li D,Song F
    Overexpression of a Stress-Responsive NAC Transcription Factor Gene ONAC022 Improves Drought and Salt Tolerance in Rice.
    Front Plant Sci, 2016. 7: p. 4
    [PMID:26834774]