PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016507553.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 337aa MW: 38245.1 Da PI: 5.0141

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016507553.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.6	8.2e-12	169	212	6	54
HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+r+N++++ Lr+++Pk + K++ +iL +++Y+k+L XP_016507553.1 169 LMAERRRRKRLNDRLSMLRSIVPKiS------KMDRTSILGDTIDYMKEL 212 589*******************66......**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.491	163	212	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	7.59E-15	165	225	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.5E-9	169	212	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.0E-11	169	218	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.31E-4	170	212	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.1E-15	170	226	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 337 aa Download sequence Send to blast
MELTQQDFLE ELLSPRIESW NSFTSGVKEL FPNAWNIESS SFYQQNPEFI AQNSSLLELI 60 SPAESSFPCP AFTPQESYPF LDAFITAPAE VDSTNYIQEE YSNRATVEEG EGVGLISTDF 120 HGHIGLGQDS SCFNNKVKME EAASRINNMG EKKSSTKVKK VEGQPSKNLM AERRRRKRLN 180 DRLSMLRSIV PKISKMDRTS ILGDTIDYMK ELIDKIHRLR EDHEMEDETK DRKFMGNYKE 240 LKPNEAFVKN PPKFDVERRN EETRIEICCA AKPGLVLSTV STIEALGLDV QQCVVSCFSD 300 FSMRASCSEA TEHRTILRSE DVQQALFKTA GYGGRCL

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	171	178	ERRRRKRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269\|PubMed:17088607}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016507553.1	0.0	PREDICTED: transcription factor bHLH93-like
Swissprot	Q9LSL1	1e-80	BH093_ARATH; Transcription factor bHLH93
TrEMBL	A0A1S4D2K0	0.0	A0A1S4D2K0_TOBAC; transcription factor bHLH93-like
STRING	XP_009778689.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA789	24	97

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65640.1	7e-78	beta HLH protein 93

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sharma N, et al. NO FLOWERING IN SHORT DAY (NFL) is a bHLH transcription factor that promotes flowering specifically under short-day conditions in Arabidopsis. Development, 2016. 143(4): p. 682-90 [PMID:26758694] Chen YS, et al. Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. Plant Mol. Biol., 2017. 93(3): p. 299-311 [PMID:27866313] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]