PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | XP_016501039.1 | ||||||||
Common Name | E2FB | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
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Family | E2F/DP | ||||||||
Protein Properties | Length: 449aa MW: 49569.1 Da PI: 4.3833 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 84.7 | 7.2e-27 | 128 | 193 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l+++ e+g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg XP_016501039.1 128 RYDSSLGLLTKKFINLIKHPEDGMLDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 193 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 8.1E-29 | 126 | 195 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 6.12E-17 | 128 | 191 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.5E-33 | 128 | 193 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 3.9E-24 | 130 | 193 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 1.82E-46 | 204 | 310 | No hit | No description |
SuperFamily | SSF144074 | 8.37E-33 | 206 | 310 | No hit | No description |
Pfam | PF16421 | 1.7E-32 | 209 | 308 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 449 aa Download sequence Send to blast |
MQPQQQQQQP SLKRQLQFSS IKPAFGDYHR FSTDPVHCSS QEPPAGIVVK TPPLKRKSAA 60 ANYGQGVGDQ NPVSEYANVN SPVQTPMSGK AGNTQKIPKT SKARSASQAV ASNAGSPSGN 120 VTPVGPCRYD SSLGLLTKKF INLIKHPEDG MLDLNKAADT LEVQKRRIYD ITNVLEGIGL 180 IEKKLKNRIQ WKGLDVSKPG EADESIASLQ GDVENLTIEE RRLDDQIRET QERLRDLSED 240 EDNQRWLFVT EDDIKSLPCF QNKTLIAIKA PHGTTLEVPD PDDAVDYPQR RYRIALRSTM 300 GPIDVYLVSQ FEEKFEEINA IEATPSVPST SGLNENATMT LATEENREVD IGMDEKENQG 360 VGSDVGTSED LMTGIMKIVP DVDNEADYWL LSDADVSITD MWRTESAIDW NELDVIQEDF 420 SIANVSTPRS ETPPTNTTEV PSAANTTGF |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 2e-25 | 123 | 194 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | HE653923 | 0.0 | HE653923.1 Nicotiana tabacum mRNA for transcription factor E2FB (E2FB gene), cultivar Samsun nn. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_016501039.1 | 0.0 | PREDICTED: transcription factor E2FB-like | ||||
Refseq | XP_016503156.1 | 0.0 | PREDICTED: transcription factor E2FB-like | ||||
Swissprot | Q9FV71 | 1e-152 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | M5BCF3 | 0.0 | M5BCF3_TOBAC; Transcription factor E2FB | ||||
STRING | XP_009802122.1 | 0.0 | (Nicotiana sylvestris) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA1077 | 24 | 84 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-152 | E2F transcription factor 1 |
Link Out ? help Back to Top | |
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Entrez Gene | 107819444 | 107821245 |
Publications ? help Back to Top | |||
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