PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016499871.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ERF

Protein Properties

Length: 241aa MW: 27064.1 Da PI: 5.4321

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016499871.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.3	1.9e-18	92	142	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++GVr+++ +g+++AeIrd + ng r++lg+f+++e Aa a+++a+ +++g XP_016499871.1 92 SFRGVRRRP-WGKFAAEIRDSTRNG--VRVWLGTFDSPEAAALAYDQAAFSMRG 142 59*****.******44465..***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.38E-19	91	151	No hit	No description
Gene3D	G3DSA:3.30.730.10	2.1E-29	92	151	IPR001471	AP2/ERF domain
SMART	SM00380	9.6E-38	92	156	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.787	92	150	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.54E-22	93	152	IPR016177	DNA-binding domain
PRINTS	PR00367	1.6E-12	93	104	IPR001471	AP2/ERF domain
Pfam	PF00847	3.2E-13	93	142	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.6E-12	132	152	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 241 aa Download sequence Send to blast
MDSSSCSSHF FYPMNSDLSS DSSWEWSNLN STNSLPFNLN DSEEMLLFGV LTNAAQETTS 60 ETVTSYHVKE EEVSSKSKVV NEIEEKPAKE KSFRGVRRRP WGKFAAEIRD STRNGVRVWL 120 GTFDSPEAAA LAYDQAAFSM RGTSAILNFP VETVQQSLRD MKCHVDEDCS PVVALKKRHS 180 MRKRSLNSKK SSNSNSKVVR EVKMEKVNVV VFEDLGADYL EQLLSSSSSD QSSCNEAFLP 240 W

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2gcc_A	3e-28	88	151	1	64	ATERF1
3gcc_A	3e-28	88	151	1	64	ATERF1
5wx9_A	4e-28	88	152	10	74	Ethylene-responsive transcription factor ERF096
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the GCC-box cis-acting elements found in the promoter regions of ethylene-responsive genes (PubMed:23057995). Acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). {ECO:0000269\|PubMed:23057995, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by wounding and infection with the fungal pathogen Botrytis cinerea. {ECO:0000269\|PubMed:28733419}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	NTU81157	0.0	U81157.1 Nicotiana tabacum S25-XP1 DNA binding protein mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016499871.1	1e-178	PREDICTED: ethylene-responsive transcription factor 1B-like
Swissprot	A0A3Q7I5Y9	7e-70	ERFC3_SOLLC; Ethylene-response factor C3
TrEMBL	A0A1S4CFH6	1e-177	A0A1S4CFH6_TOBAC; ethylene-responsive transcription factor 1B-like
STRING	XP_009606435.1	1e-133	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA21	24	1165

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	1e-57	ethylene response factor 1

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Pirrello J, et al. Functional analysis and binding affinity of tomato ethylene response factors provide insight on the molecular bases of plant differential responses to ethylene. BMC Plant Biol., 2012. 12: p. 190 [PMID:23057995] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419]