PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016498733.1

Common Name

CIP1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

DBB

Protein Properties

Length: 235aa MW: 26084.5 Da PI: 4.6749

Description

DBB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016498733.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-B_box	18	6.2e-06	4	43	5	38
zf-B_box 5 kCpeHeekelqlfCedCqqllCedClleeHkg......Ht 38 C+ +e+ +++ C ++ lC++C e H H+ XP_016498733.1 4 QCDVCEKAQATVICCADEAALCAKCDIEVHAAnklaskHQ 43 7****99*******************6566666665 PP
2	zf-B_box	28.8	2.5e-09	53	95	2	38
zf-B_box 2 eerkCpeHeekelqlfCedCqqllCedClleeHkg......Ht 38 + + C+ +++k + +fC +++ l+C+dC +++H+ H+ XP_016498733.1 53 KLPPCDICQDKAAFIFCVEDRALFCKDCDEAIHSAsslaanHQ 95 6789*****************************6566666665 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50119	9.527	1	47	IPR000315	B-box-type zinc finger
CDD	cd00021	4.43E-5	3	45	No hit	No description
SMART	SM00336	5.4E-7	4	47	IPR000315	B-box-type zinc finger
SMART	SM00336	2.2E-14	52	99	IPR000315	B-box-type zinc finger
PROSITE profile	PS50119	9.399	52	99	IPR000315	B-box-type zinc finger
Pfam	PF00643	1.4E-7	53	95	IPR000315	B-box-type zinc finger
CDD	cd00021	2.24E-6	55	98	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005622	Cellular Component	intracellular
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 235 aa Download sequence Send to blast
MKIQCDVCEK AQATVICCAD EAALCAKCDI EVHAANKLAS KHQRLHLQCL SNKLPPCDIC 60 QDKAAFIFCV EDRALFCKDC DEAIHSASSL AANHQRFLAT GIRVALSSSC NKDAVKTQLE 120 PPQPPQQNSQ QVSLKMPPHQ LSGITSPSWP VDDLLGFPDY DSSDKKELLE LGELEWLGDI 180 DLFGEQTAAE VPELSVSQSS NTHNIYKQTR YQMSYKKPRI EIPDDDEYFT VPDLG

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as negative regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation (PubMed:17605755, PubMed:18540109, PubMed:21685177). BBX24/STO and BBX25/STH function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX24/STO acts additively with BBX25/STH during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). Functions as negative regulator of photomorphogenic UV-B responses by interacting with both COP1 and HY5 (PubMed:22410790). May act as a transcription factor in the salt-stress response (PubMed:12909688). {ECO:0000269\|PubMed:12909688, ECO:0000269\|PubMed:17605755, ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:21685177, ECO:0000269\|PubMed:22410790, ECO:0000269\|PubMed:23624715}.
UniProt	Acts as negative regulator of seedling photomorphogenesis (PubMed:18540109). BBX25/STH and BBX24/STO function as transcriptional corepressors of HY5 activity, leading to the down-regulation of BBX22 expression. BBX25/STH acts additively with BBX24/STO during de-etiolation and the hypocotyl shade avoidance response (PubMed:23624715). {ECO:0000269\|PubMed:18540109, ECO:0000269\|PubMed:23624715}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian regulation with a peak before dawn. {ECO:0000269\|PubMed:17605755}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KJ767663	0.0	KJ767663.1 Nicotiana tabacum CONSTANS interacting protein 1 (CIP1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_001312926.1	1e-174	B-box zinc finger protein 24-like
Refseq	XP_009605010.1	1e-174	PREDICTED: B-box zinc finger protein 24-like
Swissprot	Q96288	2e-90	BBX24_ARATH; B-box zinc finger protein 24
Swissprot	Q9SID1	2e-90	BBX25_ARATH; B-box zinc finger protein 25
TrEMBL	A0A076FNJ2	1e-173	A0A076FNJ2_TOBAC; B-box zinc finger protein 24-like
STRING	XP_009605010.1	1e-174	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA5410	22	33

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31380.1	3e-80	salt tolerance homologue

Publications ? help Back to Top
Gangappa SN,Holm M,Botto JF Molecular interactions of BBX24 and BBX25 with HYH, HY5 HOMOLOG, to modulate Arabidopsis seedling development. Plant Signal Behav, 2014. [PMID:23733077] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Imtiaz M, et al. Identification and functional characterization of the BBX24 promoter and gene from chrysanthemum in Arabidopsis. Plant Mol. Biol., 2015. 89(1-2): p. 1-19 [PMID:26253592] Zhang X,Lin R Light signaling differentially regulates the expression of group IV of the B-box zinc finger family. Plant Signal Behav, 2017. 12(9): p. e1365213 [PMID:28922622] Job N,Yadukrishnan P,Bursch K,Datta S,Johansson H Two B-Box Proteins Regulate Photomorphogenesis by Oppositely Modulating HY5 through their Diverse C-Terminal Domains. Plant Physiol., 2018. 176(4): p. 2963-2976 [PMID:29439209]