PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016496403.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family HD-ZIP
Protein Properties Length: 766aa    MW: 85811.3 Da    PI: 6.69
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016496403.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox67.51.8e-21102157156
                     TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox   1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56 
                     r+k +++t+eq++e+e+lF+++++p++++r++L+k+lgL  rqVk+WFqNrR++ k
  XP_016496403.1 102 RKKYHRHTAEQIREMEALFKESPHPDEKQRQQLSKQLGLHPRQVKFWFQNRRTQIK 157
                     7999************************************************9877 PP
2START168.54.5e-532785033206
                     HHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS........SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEE CS
           START   3 aeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv.......dsgealrasgvvdmvlallveellddkeqWdetla....kaetl 82 
                      ++a++e+ k+a+++ep+W +s     e++n+de++++f+++++       + +ea+r++g+v+m+l++lv++++d++ qW+e+++    ka+t+
  XP_016496403.1 278 VNQAMEEVKKMATSGEPLWIRSFetgrEILNYDEYMKEFPTENSrdgrpnkRCIEASRETGIVFMELPRLVQTFMDVN-QWKEMFPsmisKAATV 371
                     57899*****************99***************99999******999*************************.**************** PP

                     EEECTT.......EEEEEEEEXX.TTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE CS
           START  83 evissg.......galqlmvael.qalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwve 168
                     +vi++g       ga+ql ++    +ls l+  + + +  y  ql+ g+w+ivdvSvd  +++  ++s+v++++lpSg+ +++ sn h+kvtwve
  XP_016496403.1 372 DVICNGegancwdGAVQLVSSFIhIVLSFLSYrKHVHYYNYPXQLSVGQWAIVDVSVDKVEDNI-DASLVKCRKLPSGCFLQEQSNAHCKVTWVE 465
                     *************9999887754156788999445667888888******************98.9***************************** PP

                     -EE--SSXXHHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
           START 169 hvdlkgrlphwllrslvksglaegaktwvatlqrqcek 206
                     h +++++++h+l+r++v+sg+a+ga++w atlq+qce+
  XP_016496403.1 466 HLECQKSTVHSLYRVIVNSGQAFGARRWIATLQQQCER 503
                     ************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.603.0E-2288153IPR009057Homeodomain-like
SuperFamilySSF466891.46E-2090160IPR009057Homeodomain-like
PROSITE profilePS5007118.09199159IPR001356Homeobox domain
SMARTSM003893.2E-19101163IPR001356Homeobox domain
PfamPF000468.8E-19102157IPR001356Homeobox domain
CDDcd000865.43E-17106157No hitNo description
PROSITE patternPS000270134157IPR017970Homeobox, conserved site
PROSITE profilePS5084830.411267506IPR002913START domain
SuperFamilySSF559612.06E-24269503No hitNo description
CDDcd088754.52E-89271502No hitNo description
SMARTSM002341.3E-41276503IPR002913START domain
PfamPF018521.1E-40278503IPR002913START domain
SuperFamilySSF559614.53E-12533753No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 766 aa     Download sequence    Send to blast
MGVVDMSNNH PPPHETKDFF PSPALSLSLA GIFRDGGNGE TEEVEDGSGS RGRPREESTV  60
EISSETSGPL RSRGSDDDFE HDDITWNEDE EDPNNNSKKK KRKKYHRHTA EQIREMEALF  120
KESPHPDEKQ RQQLSKQLGL HPRQVKFWFQ NRRTQIKAIQ ERHENSLLKA EIEKLREENK  180
GLRKTLKNPS CPNCGLACSS NDAPTLPAEE HQLRIENARL RAEVEKLRAA LGKYPIGTSP  240
NNNSSSSCSG GNEEENRSAL DYYTGIFGLE KSRIMHVVNQ AMEEVKKMAT SGEPLWIRSF  300
ETGREILNYD EYMKEFPTEN SRDGRPNKRC IEASRETGIV FMELPRLVQT FMDVNQWKEM  360
FPSMISKAAT VDVICNGEGA NCWDGAVQLV SSFIHIVLSF LSYRKHVHYY NYPXQLSVGQ  420
WAIVDVSVDK VEDNIDASLV KCRKLPSGCF LQEQSNAHCK VTWVEHLECQ KSTVHSLYRV  480
IVNSGQAFGA RRWIATLQQQ CERLLFSMAT NIPTKDTTGV ATLAGRKSIL TLAQRMTWSF  540
YRMLGASSYN TWNKIPSKTG QEDIRVASRK NLTDTGEPQG VILCAVSSIW LPVSRNLLFD  600
FLKDETRRHE WDVMSNGGPA QSVANLAKGQ DKGNAVSIQA VKLRENNMWI LQDTCTNAYE  660
SAVVYAPVDI AGMQSVITGC DSSNTAVLPS GFSILPDGIE SRGLVITSKP EDRSSEGGSL  720
LTIAFQILTS NSPTAKLSKE SVESVNNLLS CTLHKIKTSF QCDDAY
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
197102KKKKRK
297103KKKKRKK
399103KKRKK
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor required for correct morphological development and maturation of trichomes as well as for normal development of seed coat mucilage. Regulates the frequency of trichome initiation and determines trichome spacing. {ECO:0000269|PubMed:11844112}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by GEM. {ECO:0000269|PubMed:17450124}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9755151e-113HG975515.1 Solanum lycopersicum chromosome ch03, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016496403.10.0PREDICTED: homeobox-leucine zipper protein GLABRA 2-like
SwissprotP466070.0HGL2_ARATH; Homeobox-leucine zipper protein GLABRA 2
TrEMBLA0A1S4C5M30.0A0A1S4C5M3_TOBAC; homeobox-leucine zipper protein GLABRA 2-like
STRINGXP_009592772.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA62282328
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G79840.10.0HD-ZIP family protein
Publications ? help Back to Top
  1. Wu R,Citovsky V
    Adaptor proteins GIR1 and GIR2. I. Interaction with the repressor GLABRA2 and regulation of root hair development.
    Biochem. Biophys. Res. Commun., 2017. 488(3): p. 547-553
    [PMID:28526410]