PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016495062.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family ERF
Protein Properties Length: 285aa    MW: 32260.8 Da    PI: 5.0608
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016495062.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP252.31.4e-163482355
             AP2  3 ykGVrwdkkrgrWvAeIrd.psengkr.krfslgkfgtaeeAakaaiaarkkleg 55
                    + GVr+++ +g+W AeI+d       +  r +lg++ taeeAa+a+++a+  l+g
  XP_016495062.1 34 FVGVRQRP-SGKWIAEIKDtT-----KeIRMWLGTYETAEEAARAYDQAAVLLRG 82
                    78******.7*********43.....35**********************98887 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003802.5E-323396IPR001471AP2/ERF domain
CDDcd000181.41E-283389No hitNo description
Gene3DG3DSA:3.30.730.101.2E-263390IPR001471AP2/ERF domain
PROSITE profilePS5103219.7173390IPR001471AP2/ERF domain
SuperFamilySSF541719.81E-193490IPR016177DNA-binding domain
PfamPF008474.9E-113478IPR001471AP2/ERF domain
PRINTSPR003671.1E-73445IPR001471AP2/ERF domain
PRINTSPR003671.1E-75672IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 285 aa     Download sequence    Send to blast
MEINFQKQQQ TKAISMNKVA KLKGKRRSKS CNNFVGVRQR PSGKWIAEIK DTTKEIRMWL  60
GTYETAEEAA RAYDQAAVLL RGSNTRTNFV THVSQDSPLA SRIRNLLNSK KIAKKSSLEY  120
SADFISSNSV QSTSNVTSLN NSSSFSPISN CEDSISSEHA TTADYETVLS CDQEIKDESQ  180
LFHNTYIPDI DMGTSAYSSF SSSYFSSLQP EISWGFEEGF EFAQELLDIP KNVVSAEMGF  240
TEFERMKVER QISASLYAVN GVQDYMEVVY HSYESLWDQP LSNYW
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A5e-153389259ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9754496e-72HG975449.1 Solanum pennellii chromosome ch10, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016495062.10.0PREDICTED: ethylene-responsive transcription factor RAP2-11-like
SwissprotA2Q5W11e-75ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A1S4C1N60.0A0A1S4C1N6_TOBAC; ethylene-responsive transcription factor RAP2-11-like
STRINGXP_009599489.11e-180(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20182261
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.17e-25related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]