PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016493830.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

GRF

Protein Properties

Length: 379aa MW: 41503.2 Da PI: 8.6856

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016493830.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	79.5	3.2e-25	153	196	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr+v++g+k+CErH+hrgr+rsrk++e XP_016493830.1 153 DPEPGRCRRTDGKKWRCSRDVVSGHKYCERHVHRGRNRSRKPVE 196 79***************************************987 PP
2	QLQ	45.9	1.7e-16	80	115	1	36
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiq 36 s+F+ aQ+q+L+ Q+l+y++++a++PvP eLl ++ XP_016493830.1 80 SYFSLAQWQELELQALIYRHMLAGAPVPLELLHLVK 115 79*****************************97776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	4.2E-8	80	116	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	18.498	81	116	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	5.6E-12	81	114	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	24.911	153	197	IPR014977	WRC domain
Pfam	PF08879	3.0E-21	154	196	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 379 aa Download sequence Send to blast
MDFNLKQWKN QQQQNESEEE IPIPCAKLPR LVLDLDSSFS HSASDSALPL FVSEPTKLSA 60 YPLSSDSNST PTKFTRMGSS YFSLAQWQEL ELQALIYRHM LAGAPVPLEL LHLVKKSLIT 120 SSPYNYLPQS FQQYHHYQQA LVQSGYWGRT GMDPEPGRCR RTDGKKWRCS RDVVSGHKYC 180 ERHVHRGRNR SRKPVEITTM AAPVPAGGVN TANSGGSEVL NASAPHFTLS GTSPSIDLLH 240 LNQRPSESTI EKKGPLEVQN DVTGDGKSSS QILRCFFDDW PRQLEEGNNA RSNGSSVASA 300 TSLSISMPGN PSSDFSLKLS TGDRQKSGAR VTTWGTNQVT SMGGPLAEAL RSSTSNSSPT 360 SVLHQLPRGS TSEASYVST

Sequence ? help Back to Top

Protein Sequence Length: 379 aa Download sequence Send to blast

MDFNLKQWKN QQQQNESEEE IPIPCAKLPR LVLDLDSSFS HSASDSALPL FVSEPTKLSA  60
YPLSSDSNST PTKFTRMGSS YFSLAQWQEL ELQALIYRHM LAGAPVPLEL LHLVKKSLIT  120
SSPYNYLPQS FQQYHHYQQA LVQSGYWGRT GMDPEPGRCR RTDGKKWRCS RDVVSGHKYC  180
ERHVHRGRNR SRKPVEITTM AAPVPAGGVN TANSGGSEVL NASAPHFTLS GTSPSIDLLH  240
LNQRPSESTI EKKGPLEVQN DVTGDGKSSS QILRCFFDDW PRQLEEGNNA RSNGSSVASA  300
TSLSISMPGN PSSDFSLKLS TGDRQKSGAR VTTWGTNQVT SMGGPLAEAL RSSTSNSSPT  360
SVLHQLPRGS TSEASYVST

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016493830.1	0.0	PREDICTED: growth-regulating factor 3-like
Swissprot	Q8L8A7	8e-85	GRF4_ARATH; Growth-regulating factor 4
TrEMBL	A0A1S4BY56	0.0	A0A1S4BY56_TOBAC; growth-regulating factor 3-like
STRING	XP_009599016.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3283	21	38

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G52910.1	3e-62	growth-regulating factor 4

Publications ? help Back to Top
Kuijt SJ, et al. Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors. Plant Physiol., 2014. 164(4): p. 1952-66 [PMID:24532604] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]