PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016487930.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family NAC
Protein Properties Length: 353aa    MW: 41825.8 Da    PI: 6.6795
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016487930.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM154.93.5e-48571822128
             NAM   2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk 95 
                     ppG+rF P+deel+ +yLkk+v +++l+  + ikev++yk+ P++L  +    +ekewyfF++rd+ky++g+r+nra+ +gyWkatg dk++++ 
  XP_016487930.1  57 PPGYRFCPQDEELIIHYLKKRVMNERLPH-DKIKEVNLYKYSPQQLSeNYSMLGEKEWYFFTPRDRKYPNGNRPNRAAGKGYWKATGADKPIKH- 149
                     9**************************99.88**************8444445899**************************************. PP

             NAM  96 kgelvglkktLvfykgrapkgektdWvmheyrl 128
                     ++ +vg +k Lvfy+g+ pkg kt+W+mhe+r+
  XP_016487930.1 150 NDVKVGFRKALVFYEGKPPKGDKTNWIMHEFRV 182
                     999****************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.22E-5748208IPR003441NAC domain
PROSITE profilePS5100555.0356208IPR003441NAC domain
PfamPF023652.7E-2557182IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 353 aa     Download sequence    Send to blast
MEFDEQTKAN SQNPKIQELE KQKQVEDEKG LIIVKQNYNM ISEISRVNYV DDSFVFPPGY  60
RFCPQDEELI IHYLKKRVMN ERLPHDKIKE VNLYKYSPQQ LSENYSMLGE KEWYFFTPRD  120
RKYPNGNRPN RAAGKGYWKA TGADKPIKHN DVKVGFRKAL VFYEGKPPKG DKTNWIMHEF  180
RVNESRRLKR HAQDMRLDDW VLCRIYKKVD KSFKNARKEH EQDDTSISCS SIGKVENCDY  240
EGITDSYEIA RQNLKLPHHY DITFDDPGFN MDYNKYSIDN FSHFGPRSNY GIPLQPSFSP  300
GNIFWDQKGY QENCNILPMH FDVNNFYQDS YDEIQSQNIL DSVLDENSSI YKD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A4e-585620815168Stress-induced transcription factor NAC1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor of the NAC family associated with the grain protein content (GPC). Accelerates senescence and increases nutrient remobilization from leaves to developing grains. The tetraploid cultivated wheat (T.durum) and the hexaploid wheat (T.aestivum) carry a one bp insertion generating a non-functional allele of this gene. They have a delayed senescence and a lower grain protein, zinc and iron content (PubMed:17124321). {ECO:0000269|PubMed:17124321}.
UniProtTranscription factor that binds DNA motifs 5'-CGT[AG](5N)NACG[ACT][AC][AT][ACG][ACT]-3' and 5'-CACG[ACT][AC][AT][AGT][CT]-3' in target genes promoters. Promotes leaf senescence (developmental, light-induced and ABA-induced senescence) and regulates fruit yield and sugar content, probably by establishing abscisic acid (ABA) homeostasis. Activates the expression of senescence and ABA associated genes including NCED1, ABCG40, CYP707A2, SAG113, SGR1 and PAO, by directly binding to their promoters. {ECO:0000269|PubMed:29760199}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Accumulates during age-dependent and dark-induced leaf senescence. Induced by abscisic acid (ABA). {ECO:0000269|PubMed:29760199}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009603097.20.0PREDICTED: NAC transcription factor 29-like
RefseqXP_016487930.10.0PREDICTED: NAC transcription factor 29-like
SwissprotA0SPJ43e-62NAMB1_TRIDC; NAC transcription factor NAM-B1
SwissprotK4BNG72e-62NAP2_SOLLC; NAC domain-containing protein 2
TrEMBLA0A1S4BGD00.0A0A1S4BGD0_TOBAC; NAC transcription factor 29-like
STRINGXP_009759087.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA74624103
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G77450.12e-64NAC domain containing protein 32
Publications ? help Back to Top
  1. Uauy C,Distelfeld A,Fahima T,Blechl A,Dubcovsky J
    A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat.
    Science, 2006. 314(5803): p. 1298-301
    [PMID:17124321]
  2. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  3. Ma X, et al.
    The NAC Transcription Factor SlNAP2 Regulates Leaf Senescence and Fruit Yield in Tomato.
    Plant Physiol., 2018. 177(3): p. 1286-1302
    [PMID:29760199]