PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016469256.1
Common NameAn1b
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 667aa    MW: 73852.5 Da    PI: 5.0781
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016469256.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH43.84.6e-14467512454
                     HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
             HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                     +h  +ErrRR+++N++f  Lr+l+P       +K++Ka+iL  ++eY+k+L
  XP_016469256.1 467 NHVLAERRRREKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQL 512
                     7999**********************8.....8*****************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.6E-3610158IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.688463512IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.29E-15467517No hitNo description
SuperFamilySSF474591.44E-18467527IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.8E-19467529IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.2E-11467512IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.9E-18469518IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010026Biological Processtrichome differentiation
GO:0010214Biological Processseed coat development
GO:2000029Biological Processregulation of proanthocyanidin biosynthetic process
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 667 aa     Download sequence    Send to blast
MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCSQQGVLVW RDGYYNGAIK TRKTVQPMEV  60
SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI  120
GLPGKAYSKK HHIWIMCANE VDSKVFCRAI LAKSARIQVQ EDIGFINHVK SFFTEQQQPQ  180
PPKPALSEHS TSNSTTFSEP HFYSGNTPPS GNADIAQQDG GAAGEEDEEE EEEEDDEAEL  240
DSDSIAIQSE VGGAANPIAA EASELMQLDM SEAIRLGSPD DGSNNMDSDF HLVGAGNTAD  300
YQRQPDSFKA ETAISWAHFQ DLQHLPGGSS YEELSQEDTH YSQTVSTILE HFSNRSSKFS  360
STTMGCISHD SAQSAFTLCP STTVDCSPNP AHCRRRHDDS LLDGGGASPS SQWLLKSILF  420
TVPFLHTKYQ SEASPKSVDV ATVDSSSTAS RFRKGCSITS QEEPSGNHVL AERRRREKLN  480
ERFIILRSLV PFVTKMDKAS ILGDTIEYVK QLHKKVQDLE ARARHTEQSK DAVTKDQKSG  540
TATVKVLQGR GKRRMNTVEA GNIGGGQAKM TAFPLSTTED EEVVQVEVSI IESDALLELR  600
CPYKEGLLLD VMQMLRELKV EVVAIQSSLN NGIFLAELRA KVKENIYGRK ASIVEVKKSI  660
HQIIPRD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rru_A8e-131013548174Transcription factor MYC3
4ywc_A8e-131013548174Transcription factor MYC3
4ywc_B8e-131013548174Transcription factor MYC3
5gnj_A8e-14461521362Transcription factor MYC2
5gnj_B8e-14461521362Transcription factor MYC2
5gnj_E8e-14461521362Transcription factor MYC2
5gnj_F8e-14461521362Transcription factor MYC2
5gnj_G8e-14461521362Transcription factor MYC2
5gnj_I8e-14461521362Transcription factor MYC2
5gnj_M8e-14461521362Transcription factor MYC2
5gnj_N8e-14461521362Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1471476ERRRRE
2472477RRRREK
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator involved in the control of flavonoid pigmentation. {ECO:0000269|PubMed:20949001}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHQ5892090.0HQ589209.1 Nicotiana tabacum anthocyanin 1b (An1b) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016469256.10.0PREDICTED: basic helix-loop-helix protein A-like isoform X3
SwissprotE3SXU40.0BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBLA0A1S3ZY820.0A0A1S3ZY82_TOBAC; basic helix-loop-helix protein A-like isoform X3
STRINGXP_009602346.10.0(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G09820.13e-78bHLH family protein
Publications ? help Back to Top
  1. Hellens RP, et al.
    Identification of Mendel's white flower character.
    PLoS ONE, 2010. 5(10): p. e13230
    [PMID:20949001]
  2. Bai Y, et al.
    Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active.
    Planta, 2011. 234(2): p. 363-75
    [PMID:21484270]