PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016464701.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

Protein Properties

Length: 555aa MW: 62458.1 Da PI: 5.4892

Description

B3 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016464701.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	66.6	3.6e-21	124	220	1	99
EEEE-..-HHHHTT-EE--HHH.HTT..---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..E CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh..ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelv 93 f+kvlt sd++++ l++ ++ a ++ +k+ + +l+ +d++g +W++ + +r++++r++ltkGW++Fv +++L +gD+v+F + +++el+ XP_016464701.1 124 FCKVLTASDTNSNWGLTVRREDAIKCfpPLKPIQ--ELIAKDLNGSEWQFCHVFRGQPRRHLLTKGWSKFVASKRLVAGDSVIFL--RGENGELC 214 99**********************98666555..8********************************************..449999 PP EEEE-S CS B3 94 vkvfrk 99 v+v+r+ XP_016464701.1 215 VGVRRQ 220 ***996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.40.330.10	2.8E-32	118	233	IPR015300	DNA-binding pseudobarrel domain
SuperFamily	SSF101936	3.79E-24	119	222	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	3.11E-23	123	219	No hit	No description
PROSITE profile	PS50863	11.829	124	221	IPR003340	B3 DNA binding domain
Pfam	PF02362	6.3E-19	124	220	IPR003340	B3 DNA binding domain
SMART	SM01019	8.5E-18	124	221	IPR003340	B3 DNA binding domain
Pfam	PF05278	5.1E-7	397	536	IPR007942	Phospholipase-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 555 aa Download sequence Send to blast
MDGEIGSSHH QQENHVLVEG DYMYKELWKA CADPIMDLPK LGERVYYFPM NHMELLKESA 60 DQIIPLFDLP TDILCRVINI QLMVEPDTDE VYAHITLLPE ENQSDQTTPD AWSPQPLNSQ 120 FQSFCKVLTA SDTNSNWGLT VRREDAIKCF PPLKPIQELI AKDLNGSEWQ FCHVFRGQPR 180 RHLLTKGWSK FVASKRLVAG DSVIFLRGEN GELCVGVRRQ AHRRHNIGSS PVSSQTVQGV 240 LAVVSHAFAT KRLFSVYYQP RKSRFILSLS KYLEPNREKP SNQDLAQIAS NGLSTNQASV 300 DVLDCDVFGD IFLAAHPLFL ENTPESNGNC VGVASTVQNF EGWPEPQRES FTTYPQQPIP 360 EPSATISTLQ PTDTLQVMCT YSTPRQLPTE GSGFGSEQVS WAGYQVAQQY VPILSRVIMR 420 YPSTISGFKA ITGALQSVYL EMLATLVDLL EKSRIGSMDN RNQFQVIKQY LADLKFIGID 480 ISWIETRLAQ IDEVLKMEKL IQHQHTLARK IDETQFTLGQ LNQELGSVRK ELEELTPKVG 540 PSPPSKDCSI LEGLL

Sequence ? help Back to Top

Protein Sequence Length: 555 aa Download sequence Send to blast

MDGEIGSSHH QQENHVLVEG DYMYKELWKA CADPIMDLPK LGERVYYFPM NHMELLKESA  60
DQIIPLFDLP TDILCRVINI QLMVEPDTDE VYAHITLLPE ENQSDQTTPD AWSPQPLNSQ  120
FQSFCKVLTA SDTNSNWGLT VRREDAIKCF PPLKPIQELI AKDLNGSEWQ FCHVFRGQPR  180
RHLLTKGWSK FVASKRLVAG DSVIFLRGEN GELCVGVRRQ AHRRHNIGSS PVSSQTVQGV  240
LAVVSHAFAT KRLFSVYYQP RKSRFILSLS KYLEPNREKP SNQDLAQIAS NGLSTNQASV  300
DVLDCDVFGD IFLAAHPLFL ENTPESNGNC VGVASTVQNF EGWPEPQRES FTTYPQQPIP  360
EPSATISTLQ PTDTLQVMCT YSTPRQLPTE GSGFGSEQVS WAGYQVAQQY VPILSRVIMR  420
YPSTISGFKA ITGALQSVYL EMLATLVDLL EKSRIGSMDN RNQFQVIKQY LADLKFIGID  480
ISWIETRLAQ IDEVLKMEKL IQHQHTLARK IDETQFTLGQ LNQELGSVRK ELEELTPKVG  540
PSPPSKDCSI LEGLL

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldv_A	3e-96	5	279	1	287	Auxin response factor 1
4ldw_A	3e-96	5	279	1	287	Auxin response factor 1
4ldw_B	3e-96	5	279	1	287	Auxin response factor 1
4ldx_A	3e-96	5	279	1	287	Auxin response factor 1
4ldx_B	3e-96	5	279	1	287	Auxin response factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Acts as repressor of IAA2, IAA3 and IAA7. {ECO:0000269\|PubMed:12036261, ECO:0000269\|PubMed:16176952}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016464701.1	0.0	PREDICTED: uncharacterized protein LOC107787619 isoform X2
Swissprot	Q8L7G0	7e-93	ARFA_ARATH; Auxin response factor 1
TrEMBL	A0A1S3ZK04	0.0	A0A1S3ZK04_TOBAC; uncharacterized protein LOC107787619 isoform X2
STRING	XP_009783661.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G59750.2	2e-95	auxin response factor 1

Publications ? help Back to Top
Montesinos JC,Pastor-Cantizano N,Robinson DG,Marcote MJ,Aniento F Arabidopsis p24δ5 and p24δ9 facilitate Coat Protein I-dependent transport of the K/HDEL receptor ERD2 from the Golgi to the endoplasmic reticulum. Plant J., 2014. 80(6): p. 1014-30 [PMID:25312353] Marais C, et al. The Qb-SNARE Memb11 interacts specifically with Arf1 in the Golgi apparatus of Arabidopsis thaliana. J. Exp. Bot., 2015. 66(21): p. 6665-78 [PMID:26208648] Wójcikowska B,Gaj MD Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis. Plant Cell Rep., 2017. 36(6): p. 843-858 [PMID:28255787] Zhang M,Hu X,Zhu M,Xu M,Wang L Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis. Sci Rep, 2017. 7(1): p. 1395 [PMID:28469131]