PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016462046.1
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family NF-X1
Protein Properties Length: 874aa    MW: 97746.3 Da    PI: 8.442
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016462046.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X118.15.9e-06244260420
        zf-NF-X1   4 HkCqklCHeGpCppCpq 20 
                     H+C+++CHeG+CppC++
  XP_016462046.1 244 HRCSETCHEGNCPPCKA 260
                     ***************95 PP
2zf-NF-X120.11.4e-06294313120
        zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                     CG+HkC++ CHeG+C+ Cp+
  XP_016462046.1 294 CGRHKCERGCHEGDCGDCPL 313
                     ******************95 PP
3zf-NF-X120.31.2e-06401420120
        zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                     CG+H C+++C+ G+CppC++
  XP_016462046.1 401 CGRHACKRKCCDGDCPPCSE 420
                     ******************85 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF578503.04E-579150No hitNo description
PROSITE patternPS01359080143IPR019786Zinc finger, PHD-type, conserved site
CDDcd060081.33E-5177225No hitNo description
PfamPF014220.052189206IPR000967Zinc finger, NF-X1-type
SMARTSM004380.096189207IPR000967Zinc finger, NF-X1-type
CDDcd060082.68E-7231279No hitNo description
SMARTSM004383.9E-4241260IPR000967Zinc finger, NF-X1-type
PfamPF014220.001243259IPR000967Zinc finger, NF-X1-type
CDDcd060086.41E-9284327No hitNo description
PfamPF014224.6E-4294312IPR000967Zinc finger, NF-X1-type
SMARTSM004387.2E-4294313IPR000967Zinc finger, NF-X1-type
CDDcd060081.06E-9338387No hitNo description
PfamPF014220.005348367IPR000967Zinc finger, NF-X1-type
SMARTSM004380.055348368IPR000967Zinc finger, NF-X1-type
CDDcd060081.88E-8391439No hitNo description
PfamPF014224.3E-4401419IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0036401420IPR000967Zinc finger, NF-X1-type
CDDcd060087.71E-10418466No hitNo description
PfamPF014220.0086428446IPR000967Zinc finger, NF-X1-type
SMARTSM004380.0043428447IPR000967Zinc finger, NF-X1-type
SMARTSM00438130485506IPR000967Zinc finger, NF-X1-type
PfamPF014228495505IPR000967Zinc finger, NF-X1-type
PfamPF0142228514523IPR000967Zinc finger, NF-X1-type
SMARTSM0043866514559IPR000967Zinc finger, NF-X1-type
PfamPF014220.068596606IPR000967Zinc finger, NF-X1-type
SMARTSM004388.6596629IPR000967Zinc finger, NF-X1-type
SMARTSM004380.02639657IPR000967Zinc finger, NF-X1-type
PfamPF014220.3640656IPR000967Zinc finger, NF-X1-type
SMARTSM0043814702723IPR000967Zinc finger, NF-X1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0007623Biological Processcircadian rhythm
GO:0009651Biological Processresponse to salt stress
GO:0009908Biological Processflower development
GO:0010310Biological Processregulation of hydrogen peroxide metabolic process
GO:0042335Biological Processcuticle development
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:2000037Biological Processregulation of stomatal complex patterning
GO:0005634Cellular Componentnucleus
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 874 aa     Download sequence    Send to blast
MTSWSATVAP PLSPPSSDSD SDSATISDSH HHRHSDLSST IFKSYLEHSS GDHNNQQQQQ  60
HDLIKIQSFL TSSRSGALSC LICLERIRPS DPTWSCSSGC FAVFHLHCIQ SWAVQCSNLA  120
AARAVTRAAT PNDSSLLWHC PKCRVEYSKS QIPKNYYCFC GKLPDPPHDP WVLPHSCNEI  180
CGRPLKYNCG HHCLLLCHPG PCPACPKLVK SNCFCGAVED VKRCGFKNFS CNGVCKKLLD  240
CKTHRCSETC HEGNCPPCKA KGIYKCQCGK LEMKRECFDR FFRCENPCVK LLGCGRHKCE  300
RGCHEGDCGD CPLQGKRTCP CGKRFYEGIA CDAPVSVCGA TCGKMLSCGF HRCPERCHRG  360
PCIETCRVVV TKSCRCGSYR KQVPCYQDMT CERKCQKMRD CGRHACKRKC CDGDCPPCSE  420
MCDRKLRCRN HKCPAPCHRG ACAPCPVMVT ISCLCGVTHF EVPCGAEAEQ TPPKCRKPCR  480
VDRLCRHASN CKPHRCHYGA CPPCRLLCDE EYPCGHKCEL RCHGPTQPPL PEFTLKPKKR  540
RPNNQTEPTP GSSCPPCPQL VWRSCWGNHV GAERMMVCSD RTVFSCDNLC GNPLPCGNHY  600
CTKVCHALVS SASKLYGSRR PESCEECTLP CQQERKPTCR HPCPLRCHPG ECPPCKALIK  660
RSCHCGSMVH VFECIYYNSL SAKEQLTVRS CGGPCHRKLP NCTHLCPEIC HPGECSSPDQ  720
CSKKVTARCG CQNLKKELVC KDVQAAYRSN GTDPKDVSRN QYGLGILPCN SDCRSKVKAA  780
EGELQHRKSK APEEKEPETK DNVMKRRRRK GRVLEDKKTS ILQRIFAGIK KFLLFVIIII  840
ALIASVYLGY KGLLWLSDWM NEAEIQRQRR YSRT
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1534540LKPKKRR
2804809KRRRRK
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator. May mediate E2- or E3-dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. Part of a regulatory network that integrates the biosynthesis and action of abscisic acid, reactive oxygen species and cuticle components. {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:21429190, ECO:0000269|PubMed:22073231, ECO:0000269|PubMed:22516817}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with a peak of expression at or before dawn. Not regulated by biotic and abiotic stresses, by light and nutrient conditions or upon treatment with elicitors, chemicals, abscisic acid or phytohormones. {ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:22073231}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY6782980.0AY678298.1 Lycopersicon esculentum clone 56B23 chromosome 6, genomic sequence.
GenBankHG9755180.0HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009783479.10.0PREDICTED: NF-X1-type zinc finger protein NFXL2
RefseqXP_016462046.10.0PREDICTED: NF-X1-type zinc finger protein NFXL2-like
SwissprotQ9FFK80.0NFXL2_ARATH; NF-X1-type zinc finger protein NFXL2
TrEMBLA0A1S3ZCA80.0A0A1S3ZCA8_TOBAC; NF-X1-type zinc finger protein NFXL2-like
TrEMBLA0A1U7X9780.0A0A1U7X978_NICSY; NF-X1-type zinc finger protein NFXL2
STRINGXP_009783479.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA93951921
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G05660.10.0sequence-specific DNA binding transcription factors;zinc ion binding;sequence-specific DNA binding transcription factors