PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016452780.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

CAMTA

Protein Properties

Length: 1086aa MW: 121993 Da PI: 6.1165

Description

CAMTA family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016452780.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	CG-1	182.4	5.1e-57	20	136	2	118
CG-1 2 lkekkrwlkneeiaaiLenfekheltlelktrpksgsliLynrkkvryfrkDGyswkkkkdgktvrEdhekLKvggvevlycyYahseenptfqr 96 l+ ++rwl++ ei++iL+n++k++++ e+++rp+sgsl+L++rk++ryfrkDG+sw+kkkdgktv+E+he+LK g+++vl+cyYah+een++fqr XP_016452780.1 20 LEAQHRWLRPAEICEILKNYQKFRIAPEPPNRPPSGSLFLFDRKVLRYFRKDGHSWRKKKDGKTVKEAHERLKAGSIDVLHCYYAHGEENENFQR 114 5679***************************************************************************************** PP CG-1 97 rcywlLeeelekivlvhylevk 118 r+yw+Leee+++ivlvhy+evk XP_016452780.1 115 RSYWMLEEEMSHIVLVHYREVK 136 *****************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51437	83.558	15	141	IPR005559	CG-1 DNA-binding domain
SMART	SM01076	1.9E-79	18	136	IPR005559	CG-1 DNA-binding domain
Pfam	PF03859	3.7E-50	21	134	IPR005559	CG-1 DNA-binding domain
Pfam	PF01833	1.8E-4	498	576	IPR002909	IPT domain
SuperFamily	SSF81296	6.44E-15	498	584	IPR014756	Immunoglobulin E-set
CDD	cd00204	1.91E-14	684	793	No hit	No description
PROSITE profile	PS50297	19.465	684	805	IPR020683	Ankyrin repeat-containing domain
SuperFamily	SSF48403	1.38E-18	689	795	IPR020683	Ankyrin repeat-containing domain
Gene3D	G3DSA:1.25.40.20	7.9E-19	690	799	IPR020683	Ankyrin repeat-containing domain
Pfam	PF12796	1.1E-8	706	797	IPR020683	Ankyrin repeat-containing domain
SMART	SM00248	0.0016	734	763	IPR002110	Ankyrin repeat
PROSITE profile	PS50088	10.152	734	766	IPR002110	Ankyrin repeat
SMART	SM00248	22	773	802	IPR002110	Ankyrin repeat
SuperFamily	SSF52540	3.45E-7	902	959	IPR027417	P-loop containing nucleoside triphosphate hydrolase
SMART	SM00015	50	908	930	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	7.346	910	938	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	0.17	911	929	IPR000048	IQ motif, EF-hand binding site
SMART	SM00015	0.0042	931	953	IPR000048	IQ motif, EF-hand binding site
PROSITE profile	PS50096	9.285	932	956	IPR000048	IQ motif, EF-hand binding site
Pfam	PF00612	4.9E-4	934	953	IPR000048	IQ motif, EF-hand binding site

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 1086 aa Download sequence Send to blast
MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF 60 DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML 120 EEEMSHIVLV HYREVKGNRT NFSRTREPQE AAPRFQETDE DVHSSEVDSS ASTKFYPNDY 180 QVNSQVTDTT SLSSVQASEY EDAESAYNQH PTSGFHSFLD AQPSMTQKAG EGLAVPYHPI 240 PFSRNKSGNT ANTYIPSRNL DFPSWETTSV NNPAAYQSYH FQPSSQSGAN NMTHEQGNTK 300 TGQVFLNDFK RQERQNRIDG LGDWQTSEGD AAFISKWSMD QKLHPDLASD HTIRSSAAYN 360 VELHNSLEAS HILPSHQDKH PMQNELPSQL SDPNVGGSLN ADLDHNLSIG VRTDHSSLKQ 420 PLLDGVLREG LKKLDSFDRW MSKELEDVSE PHMQSNSSSY WDNVGDDDGV DNSTIASQVQ 480 LDTYMLSPSL SQDQFFSIID FSPSWAFAGS EIKVLITGKF LKSQPEVEKC SWACMFGELE 540 VPAEVIADGV LRCHTPIQKA GRVPFYITCC NRLACSEVRE FEFRVTEGQD ADVANANSCS 600 SSESLLHMRF GKLLSLESTV SLSSPPRSED DVSHVCSKIN SLLNEDDNEW EEMLNLTYEN 660 NFMAEKVKDQ LLQKLLKEKL RVWLLQKVAE GGKGPNVLDE GGQGVLHFAA ALGYDWAIPP 720 TIAAGVSVNF RDVNGWTALH WAASYGRERT VGFLISLGAA PGALTDPTPK HPSGRTPADL 780 ASSNGHKGIA GYLAESSLSF HLSSLELKEM KQGENVQPFG EAVQTVSERS ATPAWDGDWP 840 HGVSLKDSLA AVRNATQAAA RIHQVFRVQS FQRKQLKEHG GSEFGLSDEH ALSLLALKTN 900 KAGQHDEPVH TAAVRIQNKF RSWKGRRDYL LIRQRIIKIQ AHVRGHQVRN KYKNIIWSVG 960 ILEKVILRWR RKGSGLRGFK PEATLTEGSD TQDRPVQEDD YDFLKEGRKQ TEQRLQKALA 1020 RVKSMVQYPE ARDQYRRLLN VVSDMKDTTT TSDGAPSNSV EAADFGDDLI DLDDLLDDDT 1080 FMSTAP

Sequence ? help Back to Top

Protein Sequence Length: 1086 aa Download sequence Send to blast

MADSRRYGLN AQLDIDQILL EAQHRWLRPA EICEILKNYQ KFRIAPEPPN RPPSGSLFLF  60
DRKVLRYFRK DGHSWRKKKD GKTVKEAHER LKAGSIDVLH CYYAHGEENE NFQRRSYWML  120
EEEMSHIVLV HYREVKGNRT NFSRTREPQE AAPRFQETDE DVHSSEVDSS ASTKFYPNDY  180
QVNSQVTDTT SLSSVQASEY EDAESAYNQH PTSGFHSFLD AQPSMTQKAG EGLAVPYHPI  240
PFSRNKSGNT ANTYIPSRNL DFPSWETTSV NNPAAYQSYH FQPSSQSGAN NMTHEQGNTK  300
TGQVFLNDFK RQERQNRIDG LGDWQTSEGD AAFISKWSMD QKLHPDLASD HTIRSSAAYN  360
VELHNSLEAS HILPSHQDKH PMQNELPSQL SDPNVGGSLN ADLDHNLSIG VRTDHSSLKQ  420
PLLDGVLREG LKKLDSFDRW MSKELEDVSE PHMQSNSSSY WDNVGDDDGV DNSTIASQVQ  480
LDTYMLSPSL SQDQFFSIID FSPSWAFAGS EIKVLITGKF LKSQPEVEKC SWACMFGELE  540
VPAEVIADGV LRCHTPIQKA GRVPFYITCC NRLACSEVRE FEFRVTEGQD ADVANANSCS  600
SSESLLHMRF GKLLSLESTV SLSSPPRSED DVSHVCSKIN SLLNEDDNEW EEMLNLTYEN  660
NFMAEKVKDQ LLQKLLKEKL RVWLLQKVAE GGKGPNVLDE GGQGVLHFAA ALGYDWAIPP  720
TIAAGVSVNF RDVNGWTALH WAASYGRERT VGFLISLGAA PGALTDPTPK HPSGRTPADL  780
ASSNGHKGIA GYLAESSLSF HLSSLELKEM KQGENVQPFG EAVQTVSERS ATPAWDGDWP  840
HGVSLKDSLA AVRNATQAAA RIHQVFRVQS FQRKQLKEHG GSEFGLSDEH ALSLLALKTN  900
KAGQHDEPVH TAAVRIQNKF RSWKGRRDYL LIRQRIIKIQ AHVRGHQVRN KYKNIIWSVG  960
ILEKVILRWR RKGSGLRGFK PEATLTEGSD TQDRPVQEDD YDFLKEGRKQ TEQRLQKALA  1020
RVKSMVQYPE ARDQYRRLLN VVSDMKDTTT TSDGAPSNSV EAADFGDDLI DLDDLLDDDT  1080
FMSTAP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4hb5_A	6e-12	685	793	20	122	Engineered Protein
4hb5_B	6e-12	685	793	20	122	Engineered Protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds to the DNA consensus sequence 5'-[ACG]CGCG[GTC]-3'. Binds calmodulin in a calcium-dependent manner in vitro (PubMed:12218065). Regulates transcriptional activity in response to calcium signals (Probable). Involved in freezing tolerance in association with CAMTA1 and CAMTA2 (PubMed:23581962). Required for the cold-induced expression of DREB1B/CBF1, DREB1C/CBF2, ZAT12 and GOLS3 (PubMed:19270186). Involved in response to cold. Contributes together with CAMTA5 to the positive regulation of the cold-induced expression of DREB1A/CBF3, DREB1B/CBF1 and DREB1C/CBF2 (PubMed:28351986). Involved together with CAMTA2 and CAMTA4 in the positive regulation of a general stress response (GSR) (PubMed:25039701). Involved in the regulation of GSR amplitude downstream of MEKK1 (PubMed:25157030). Involved in the regulation of a set of genes involved in defense responses against pathogens (PubMed:18298954). Involved in the regulation of both basal resistance and systemic acquired resistance (SAR) (PubMed:21900483). Acts as negative regulator of plant immunity (PubMed:19122675, PubMed:21900483, PubMed:22345509, PubMed:28407487). Binds to the promoter of the defense-related gene EDS1 and represses its expression (PubMed:19122675). Binds to the promoter of the defense-related gene NDR1 and represses its expression (PubMed:22345509). Involved in defense against insects (PubMed:23072934, PubMed:22371088). Required for tolerance to the generalist herbivore Trichoplusia ni, and contributes to the positive regulation of genes associated with glucosinolate metabolism (PubMed:23072934). Required for tolerance to Bradysia impatiens larvae. Mediates herbivore-induced wound response (PubMed:22371088). Required for wound-induced jasmonate accumulation (PubMed:23072934, PubMed:22371088). Involved in the regulation of ethylene-induced senescence by binding to the promoter of the senescence-inducer gene EIN3 and repressing its expression (PubMed:22345509). {ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:18298954, ECO:0000269\|PubMed:19122675, ECO:0000269\|PubMed:19270186, ECO:0000269\|PubMed:21900483, ECO:0000269\|PubMed:22345509, ECO:0000269\|PubMed:22371088, ECO:0000269\|PubMed:23072934, ECO:0000269\|PubMed:23581962, ECO:0000269\|PubMed:25039701, ECO:0000269\|PubMed:25157030, ECO:0000269\|PubMed:28351986, ECO:0000269\|PubMed:28407487, ECO:0000305\|PubMed:11925432}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat shock, UVB, salt, wounding, ethylene and methyl jasmonate (PubMed:11162426, PubMed:12218065). Induced by infection with the fungal pathogen Golovinomyces cichoracearum (powdery mildew) and the bacterial pathogen Pseudomonas syringae pv tomato strain DC3000 (PubMed:22345509). {ECO:0000269\|PubMed:11162426, ECO:0000269\|PubMed:12218065, ECO:0000269\|PubMed:22345509}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF253511	0.0	AF253511.1 Nicotiana tabacum anther ethylene-upregulated protein ER1 (ER1) mRNA, partial cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016452780.1	0.0	PREDICTED: calmodulin-binding transcription activator 3-like isoform X3
Swissprot	Q8GSA7	0.0	CMTA3_ARATH; Calmodulin-binding transcription activator 3
TrEMBL	A0A1S3YL03	0.0	A0A1S3YL03_TOBAC; calmodulin-binding transcription activator 3-like isoform X3
STRING	XP_009613615.1	0.0	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22300.2	0.0	signal responsive 1

Publications ? help Back to Top
Zhang L,Du L,Shen C,Yang Y,Poovaiah BW Regulation of plant immunity through ubiquitin-mediated modulation of Ca(2+) -calmodulin-AtSR1/CAMTA3 signaling. Plant J., 2014. 78(2): p. 269-81 [PMID:24528504] Benn G, et al. A key general stress response motif is regulated non-uniformly by CAMTA transcription factors. Plant J., 2014. 80(1): p. 82-92 [PMID:25039701] Rahman H,Yang J,Xu YP,Munyampundu JP,Cai XZ Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae. Front Plant Sci, 2016. 7: p. 177 [PMID:26973658] Benn G, et al. Plastidial metabolite MEcPP induces a transcriptionally centered stress-response hub via the transcription factor CAMTA3. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(31): p. 8855-60 [PMID:27432993] Kidokoro S, et al. Different Cold-Signaling Pathways Function in the Responses to Rapid and Gradual Decreases in Temperature. Plant Cell, 2017. 29(4): p. 760-774 [PMID:28351986] Lolle S, et al. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Cell Host Microbe, 2017. 21(4): p. 518-529.e4 [PMID:28407487] Kim YS, et al. CAMTA-Mediated Regulation of Salicylic Acid Immunity Pathway Genes in Arabidopsis Exposed to Low Temperature and Pathogen Infection. Plant Cell, 2017. 29(10): p. 2465-2477 [PMID:28982964] Jacob F, et al. A dominant-interfering camta3 mutation compromises primary transcriptional outputs mediated by both cell surface and intracellular immune receptors in Arabidopsis thaliana. New Phytol., 2018. 217(4): p. 1667-1680 [PMID:29226970]