PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_016451603.1

Organism

Nicotiana tabacum

Taxonomic ID

4097

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

ZF-HD

Protein Properties

Length: 262aa MW: 29121.4 Da PI: 8.6707

Description

ZF-HD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_016451603.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	ZF-HD_dimer	112.4	2.3e-35	49	106	3	59
ZF-HD_dimer 3 kvrYkeClkNhAaslGghavDGCgEfmpsegee.gtaaalkCaACgCHRnFHRrevee 59 +v+YkeClkNhAas+GghavDGCgEfmps++++ +++++lkCaACgCHRnFHRre++e XP_016451603.1 49 AVTYKECLKNHAASIGGHAVDGCGEFMPSPDSTpSNPTSLKCAACGCHRNFHRREPAE 106 799****************************9******************9876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF04770	1.0E-29	50	104	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
ProDom	PD125774	2.0E-20	50	110	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
TIGRFAMs	TIGR01566	5.3E-31	51	103	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
PROSITE profile	PS51523	27.243	52	103	IPR006456	ZF-HD homeobox protein, Cys/His-rich dimerisation domain
SuperFamily	SSF46689	1.79E-19	149	220	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	3.1E-29	153	221	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01565	2.3E-24	159	216	IPR006455	Homeodomain, ZF-HD class

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 262 aa Download sequence Send to blast
MELTCGSNPT KSTPDSENDT PPLIKPLSFS NGILKNHHFY HHQQPPSAAV TYKECLKNHA 60 ASIGGHAVDG CGEFMPSPDS TPSNPTSLKC AACGCHRNFH RREPAEDSSP THFPSHFINF 120 RHHILPPIRR FSPSSSSSPP PPFQPQPITP KVEHNPSGRK RFRTKFTQQQ KEKMHSFSEK 180 LGWKLQKCDE AKVEEFCNEV GVGKGVLRVW MHNNKNTFAK KEELQNGNNN SNGFNIHGSS 240 SNEDHNNCGL HLHISTNGSS SS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1wh7_A	7e-22	160	217	18	75	ZF-HD homeobox family protein
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Putative transcription factor.
UniProt	Transcription factor involved in the up-regulation of several stress-inducible genes. Acts as a transcriptional activator by interacting with MED25 and NAC proteins. Involved in increased drought tolerance. {ECO:0000269\|PubMed:16428600, ECO:0000269\|PubMed:17233795}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by abscisic acid and by drought and salt stress. Not induced by cold. {ECO:0000269\|PubMed:17233795}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009620302.1	0.0	PREDICTED: zinc-finger homeodomain protein 9-like
Swissprot	Q9LHF0	4e-58	ZHD9_ARATH; Zinc-finger homeodomain protein 9
Swissprot	Q9SEZ1	4e-58	ZHD11_ARATH; Zinc-finger homeodomain protein 11
TrEMBL	A0A1S3YHU2	0.0	A0A1S3YHU2_TOBAC; zinc-finger homeodomain protein 9-like
STRING	XP_009620302.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1088	24	85

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15210.1	3e-51	homeobox protein 30

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470]