PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_016446672.1
Common NameTGA1, TGA1A
Organism
Nicotiana tabacum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bZIP
Protein Properties Length: 373aa    MW: 42303.1 Da    PI: 6.3248
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_016446672.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_131.83e-1088124541
                     CHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS
          bZIP_1   5 krerrkqkNReAArrsRqRKkaeieeLeekvkeLeae 41 
                     k+ rr+++NReAAr+sR+RKka++++Le+   +L + 
  XP_016446672.1  88 KVLRRLAQNREAARKSRLRKKAYVQQLENSKLKLIQL 124
                     789*************************865555544 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.20.5.1701.4E-782133No hitNo description
SMARTSM003380.001884137IPR004827Basic-leucine zipper domain
PROSITE profilePS502178.85286130IPR004827Basic-leucine zipper domain
PfamPF001701.9E-788119IPR004827Basic-leucine zipper domain
SuperFamilySSF579592.81E-688129No hitNo description
PROSITE patternPS00036091106IPR004827Basic-leucine zipper domain
PfamPF141448.1E-29175249IPR025422Transcription factor TGA like domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 373 aa     Download sequence    Send to blast
MNSSTYTQFA ASRRMGICDP IHQLGMWDDF NSSFPSTSAT MILEVDKCLE DQIPIMEKRL  60
DNETEDTSHG TVGTSNRYEP ETSKPVEKVL RRLAQNREAA RKSRLRKKAY VQQLENSKLK  120
LIQLEQELER ARKQGMCVGG GVDASQLSYS GTASSGTAVF DMEYGHWVEE QTRQTNDLRI  180
ALHSQIGEAE LRIIVDGYLN HYFDLFRMKA TAAKADVLYI MSGMWKTSAE RFFMWIGGFR  240
PSELLKVLTP HLELLTEQQL REVCNLTQSC QQAEDALSQG MVKLHQILAE AVAAGRLGEG  300
NYTLPQMGPA IEKLEDLVRF VNQADHLRQE TLQQMSRILN TCQAAQGLLA LGEYFERLRV  360
LSSQWATRLR EPT
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00642SELEX26531826Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch P14232
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankX164490.0X16449.1 Tobacco mRNA for TGA1a DNA-binding protein.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016446672.10.0PREDICTED: TGACG-sequence-specific DNA-binding protein TGA-1A isoform X1
SwissprotP142320.0TGA1A_TOBAC; TGACG-sequence-specific DNA-binding protein TGA-1A
TrEMBLA0A1S3Y4610.0A0A1S3Y461_TOBAC; TGACG-sequence-specific DNA-binding protein TGA-1A isoform X1
STRINGXP_009593001.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA7802497
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G65210.51e-159bZIP family protein
Publications ? help Back to Top
  1. Klinedinst S,Pascuzzi P,Redman J,Desai M,Arias J
    A xenobiotic-stress-activated transcription factor and its cognate target genes are preferentially expressed in root tip meristems.
    Plant Mol. Biol., 2000. 42(5): p. 679-88
    [PMID:10809441]
  2. Weigel RR,Bäuscher C,Pfitzner AJ,Pfitzner UM
    NIMIN-1, NIMIN-2 and NIMIN-3, members of a novel family of proteins from Arabidopsis that interact with NPR1/NIM1, a key regulator of systemic acquired resistance in plants.
    Plant Mol. Biol., 2001. 46(2): p. 143-60
    [PMID:11442055]
  3. Johnson C,Boden E,Desai M,Pascuzzi P,Arias J
    In vivo target promoter-binding activities of a xenobiotic stress-activated TGA factor.
    Plant J., 2001. 28(2): p. 237-43
    [PMID:11722767]
  4. Katagiri F,Seipel K,Chua NH
    Identification of a novel dimer stabilization region in a plant bZIP transcription activator.
    Mol. Cell. Biol., 1992. 12(11): p. 4809-16
    [PMID:1406663]
  5. Ndamukong I, et al.
    SA-inducible Arabidopsis glutaredoxin interacts with TGA factors and suppresses JA-responsive PDF1.2 transcription.
    Plant J., 2007. 50(1): p. 128-39
    [PMID:17397508]
  6. Katagiri F,Lam E,Chua NH
    Two tobacco DNA-binding proteins with homology to the nuclear factor CREB.
    Nature, 1989. 340(6236): p. 727-30
    [PMID:2528073]
  7. Lam E,Lam YK
    Binding site requirements and differential representation of TGF factors in nuclear ASF-1 activity.
    Nucleic Acids Res., 1995. 23(18): p. 3778-85
    [PMID:7479010]
  8. Miao ZH,Lam E
    Construction of a trans-dominant inhibitor for members of the TGA family of transcription factors conserved in higher plants.
    Plant J., 1995. 7(6): p. 887-96
    [PMID:7599649]
  9. Pascuzzi P,Hamilton D,Bodily K,Arias J
    Auxin-induced stress potentiates trans-activation by a conserved plant basic/leucine-zipper factor.
    J. Biol. Chem., 1998. 273(41): p. 26631-7
    [PMID:9756903]