PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009803796.1

Common Name

An1

Organism

Nicotiana sylvestris

Taxonomic ID

4096

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

bHLH

Protein Properties

Length: 666aa MW: 73611.1 Da PI: 4.891

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009803796.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	43.8	4.6e-14	470	516	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +h +ErrRR+++N++f Lr+l+P +K++Ka+iL ++eY+k+L+ XP_009803796.1 470 NHVLAERRRREKLNERFIILRSLVPFV-----TKMDKASILGDTIEYVKQLR 516 7999********************8.....8***************95 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	4.0E-48	10	187	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.688	466	515	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.7E-19	470	531	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.3E-11	470	515	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.53E-18	470	527	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	6.68E-16	470	520	No hit	No description
SMART	SM00353	4.3E-18	472	521	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 666 aa Download sequence Send to blast
MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCPQQGALVW RDGYYNGAIK TRKTVQPMEV 60 SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI 120 GLPGKAYSKK HHIWIMGANE VDSKVFCRAI LAKTVVGIPL LDGVLELGTT ERVQEEIGFI 180 NHVKSFFTEQ QQPQLPKPAL SEHSTSNPTT FSEPHFYSGN TSPSANVDIA HQDGGAAGEE 240 DEEEEEEEDD DEAELDSDSI AIQSAANPIA VEASELMQLD VSEAIQLGSP DDDSDNMDSD 300 FHLVGAGNTA HDYQRQADSF KAETAISWPH FQDLQQLPGG SSYDELSQED THYSQTVSTI 360 LEHRSSKFSS TTMGCISHDS AQSAFTLCPS TTVCSPNPAH CRHDDSLVDG GGASQWLLKS 420 ILFTVPFLHT KYQSEASPKS RDVATVDSSS TASRFRKGCS ITSQEEPSGN HVLAERRRRE 480 KLNERFIILR SLVPFVTKMD KASILGDTIE YVKQLRKKVQ DLEARARDTE HSRDADKKGG 540 TATVKVLQGR GKRRMNTVDG SVGGGQATIT ASPPSTTENE EVVQVQVSII ESDALVELRC 600 PYKEGLLLNV MQMLRELKVE VVAIQSALNN GVFLAELRAK VKENIYGRKA SILEVKRSIH 660 QIIPRD

Sequence ? help Back to Top

Protein Sequence Length: 666 aa Download sequence Send to blast

MTEIPPNSQM QTMLQKAVQS VQWTYTLFWQ LCPQQGALVW RDGYYNGAIK TRKTVQPMEV  60
SAEEASLHRS QQLRELYESL SAGESNQPAR RPSAALSPED LTESEWFYLM CVSFSFPPGI  120
GLPGKAYSKK HHIWIMGANE VDSKVFCRAI LAKTVVGIPL LDGVLELGTT ERVQEEIGFI  180
NHVKSFFTEQ QQPQLPKPAL SEHSTSNPTT FSEPHFYSGN TSPSANVDIA HQDGGAAGEE  240
DEEEEEEEDD DEAELDSDSI AIQSAANPIA VEASELMQLD VSEAIQLGSP DDDSDNMDSD  300
FHLVGAGNTA HDYQRQADSF KAETAISWPH FQDLQQLPGG SSYDELSQED THYSQTVSTI  360
LEHRSSKFSS TTMGCISHDS AQSAFTLCPS TTVCSPNPAH CRHDDSLVDG GGASQWLLKS  420
ILFTVPFLHT KYQSEASPKS RDVATVDSSS TASRFRKGCS ITSQEEPSGN HVLAERRRRE  480
KLNERFIILR SLVPFVTKMD KASILGDTIE YVKQLRKKVQ DLEARARDTE HSRDADKKGG  540
TATVKVLQGR GKRRMNTVDG SVGGGQATIT ASPPSTTENE EVVQVQVSII ESDALVELRC  600
PYKEGLLLNV MQMLRELKVE VVAIQSALNN GVFLAELRAK VKENIYGRKA SILEVKRSIH  660
QIIPRD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	6e-17	10	187	9	192	Transcription factor MYC3
4rqw_B	6e-17	10	187	9	192	Transcription factor MYC3
4rs9_A	6e-17	10	187	9	192	Transcription factor MYC3
4yz6_A	6e-17	10	187	9	192	Transcription factor MYC3
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	474	479	ERRRRE
2	475	480	RRRREK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the control of flavonoid pigmentation. {ECO:0000269\|PubMed:20949001}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	HQ589210	0.0	HQ589210.1 Nicotiana sylvestris anthocyanin 1-like protein (An1) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009803796.1	0.0	PREDICTED: basic helix-loop-helix protein A isoform X2
Swissprot	E3SXU4	0.0	BHLHW_PEA; Basic helix-loop-helix protein A
TrEMBL	A0A1U7YP84	0.0	A0A1U7YP84_NICSY; basic helix-loop-helix protein A isoform X2
STRING	XP_009803795.1	0.0	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G09820.1	6e-90	bHLH family protein

Link Out ? help Back to Top
Entrez Gene	104249116

Publications ? help Back to Top
Hellens RP, et al. Identification of Mendel's white flower character. PLoS ONE, 2010. 5(10): p. e13230 [PMID:20949001] Bai Y, et al. Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active. Planta, 2011. 234(2): p. 363-75 [PMID:21484270]