PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009798626.1

Organism

Nicotiana sylvestris

Taxonomic ID

4096

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 434aa MW: 48557.7 Da PI: 6.9546

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009798626.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.6	3.5e-30	199	258	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt + +Cpv+k+v+r+ ed +++++tYeg+Hnh+ XP_009798626.1 199 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVSpSCPVRKQVQRCFEDMSILITTYEGTHNHP 258 58************************999**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.6E-31	184	260	IPR003657	WRKY domain
SuperFamily	SSF118290	1.44E-27	192	260	IPR003657	WRKY domain
PROSITE profile	PS50811	28.644	194	260	IPR003657	WRKY domain
SMART	SM00774	2.9E-36	199	259	IPR003657	WRKY domain
Pfam	PF03106	1.3E-26	200	258	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 434 aa Download sequence Send to blast
MNTNSRDSSL TYKKNQEDQL NSTKAQIGEA KEENEKLKSM LSKIMKDYQS LQMHFQGISH 60 KPQNSKDIIA TSIEQEEEVD LVSLSLGRSS REFKQDEKEY DQNECKDIKK QSKLFDGLEL 120 GLDCRFSLDF TEVTKNYDDS PENSFEESKK EHITEPCVQN YTSSKMPRIC GDEDEDFLQQ 180 NPQKKARVSI RAVCDTTTMN DGCQWRKYGQ KIAKGNPCPR AYYRCTVSPS CPVRKQVQRC 240 FEDMSILITT YEGTHNHPLP FSATAMASTT SAAASMLSCT SSSTSQQGIT DANNNNLNGF 300 NFTTSNCNNL ATHAPNTFYL PKTSISTSQT HPTITLDFTT VPATTSSSTH TFSSQRYSST 360 SLNFSTLPST PPSSSFINSF KSQVGASYLG RPCFSQPFTS NNTRNTEDSD GARNSNMWIQ 420 KRSKVSHLGF DSVT

Sequence ? help Back to Top

Protein Sequence Length: 434 aa Download sequence Send to blast

MNTNSRDSSL TYKKNQEDQL NSTKAQIGEA KEENEKLKSM LSKIMKDYQS LQMHFQGISH  60
KPQNSKDIIA TSIEQEEEVD LVSLSLGRSS REFKQDEKEY DQNECKDIKK QSKLFDGLEL  120
GLDCRFSLDF TEVTKNYDDS PENSFEESKK EHITEPCVQN YTSSKMPRIC GDEDEDFLQQ  180
NPQKKARVSI RAVCDTTTMN DGCQWRKYGQ KIAKGNPCPR AYYRCTVSPS CPVRKQVQRC  240
FEDMSILITT YEGTHNHPLP FSATAMASTT SAAASMLSCT SSSTSQQGIT DANNNNLNGF  300
NFTTSNCNNL ATHAPNTFYL PKTSISTSQT HPTITLDFTT VPATTSSSTH TFSSQRYSST  360
SLNFSTLPST PPSSSFINSF KSQVGASYLG RPCFSQPFTS NNTRNTEDSD GARNSNMWIQ  420
KRSKVSHLGF DSVT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	3e-20	191	260	2	74	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016502533.1	0.0	PREDICTED: probable WRKY transcription factor 72 isoform X1
Swissprot	A0A3Q7GFB5	7e-89	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1S4CMR3	0.0	A0A1S4CMR3_TOBAC; probable WRKY transcription factor 72 isoform X1
STRING	XP_009798626.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	3e-59	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]