PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009796718.1
Organism
Nicotiana sylvestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family NAC
Protein Properties Length: 399aa    MW: 44801.3 Da    PI: 4.923
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009796718.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM166.31e-51291561128
             NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 
                     l+pGfrFhPtdeelv +yL++k+ gk++++ ++++e+d+yk+ePw+L +  ++k+++ ewyfFs+ dkky +g+r nrat +gyWkatgkd+ v 
  XP_009796718.1  29 LAPGFRFHPTDEELVRYYLRRKACGKPFRF-QAVTEIDVYKSEPWELAEysSLKSRDLEWYFFSPVDKKYGNGSRLNRATGQGYWKATGKDRFVR 122
                     579*************************99.88**************84346777888************************************* PP

             NAM  94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128
                     + k++++g+kktLvf++grap+g++t+Wvmheyrl
  XP_009796718.1 123 H-KSQTIGMKKTLVFHSGRAPDGQRTNWVMHEYRL 156
                     9.999****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019412.22E-6223179IPR003441NAC domain
PROSITE profilePS5100557.8229179IPR003441NAC domain
PfamPF023653.9E-2831156IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 399 aa     Download sequence    Send to blast
MEQEGSLVVV VAAAGAVTVA APARAPTSLA PGFRFHPTDE ELVRYYLRRK ACGKPFRFQA  60
VTEIDVYKSE PWELAEYSSL KSRDLEWYFF SPVDKKYGNG SRLNRATGQG YWKATGKDRF  120
VRHKSQTIGM KKTLVFHSGR APDGQRTNWV MHEYRLADEE LEKAGIVQDS FVLCRIFQKS  180
GLGPPNGDRY APFVEEEWDD DVAMIPGGEA EDDMANGDEA RVEGNDLDQD ALRKAPRYIE  240
NLIEPQSLPF VCKRESSEDA ELLSLSQSKR SKHDDPSSSR VNGSEDSTIT SQDPPTTMMT  300
KTNCSPTLLG FPLLESTETK EGQPSNPPTF DSSNLEKSVP PGYLKFISNL ENGILNVSME  360
RETLKIEVMR AQAMINLLQS RVDLLTKENE DMRRIVREG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A4e-522817916165NO APICAL MERISTEM PROTEIN
1ut4_B4e-522817916165NO APICAL MERISTEM PROTEIN
1ut7_A4e-522817916165NO APICAL MERISTEM PROTEIN
1ut7_B4e-522817916165NO APICAL MERISTEM PROTEIN
3swm_A4e-522817919168NAC domain-containing protein 19
3swm_B4e-522817919168NAC domain-containing protein 19
3swm_C4e-522817919168NAC domain-containing protein 19
3swm_D4e-522817919168NAC domain-containing protein 19
3swp_A4e-522817919168NAC domain-containing protein 19
3swp_B4e-522817919168NAC domain-containing protein 19
3swp_C4e-522817919168NAC domain-containing protein 19
3swp_D4e-522817919168NAC domain-containing protein 19
4dul_A4e-522817916165NAC domain-containing protein 19
4dul_B4e-522817916165NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC050 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). Regulates siRNA-dependent post-transcriptional gene silencing (PTGS) through SGS3 expression modulation (PubMed:28207953). Required during pollen development (PubMed:19237690). {ECO:0000269|PubMed:19237690, ECO:0000269|PubMed:24045019, ECO:0000269|PubMed:25578968, ECO:0000269|PubMed:26617990, ECO:0000269|PubMed:28207953}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by type III effector proteins (TTEs) secreted by the pathogenic bacteria P.syringae pv. tomato DC3000 during basal defense. {ECO:0000269|PubMed:16553893}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009796718.10.0PREDICTED: NAC domain-containing protein 78-like
RefseqXP_016464323.10.0PREDICTED: NAC domain-containing protein 78-like
SwissprotQ9SQY01e-108NAC52_ARATH; NAC domain containing protein 52
TrEMBLA0A1S3ZJ250.0A0A1S3ZJ25_TOBAC; NAC domain-containing protein 78-like
TrEMBLA0A1U7Y0R10.0A0A1U7Y0R1_NICSY; NAC domain-containing protein 78-like
STRINGXP_009796718.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA31402448
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G10490.23e-96NAC domain containing protein 52
Publications ? help Back to Top
  1. Higgins JD,Ferdous M,Osman K,Franklin FC
    The RecQ helicase AtRECQ4A is required to remove inter-chromosomal telomeric connections that arise during meiotic recombination in Arabidopsis.
    Plant J., 2011. 65(3): p. 492-502
    [PMID:21265901]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Zhang S, et al.
    C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association.
    Cell Discov, 2019.
    [PMID:26617990]
  4. Butel N,Le Masson I,Bouteiller N,Vaucheret H,Elmayan T
    sgs1: a neomorphic nac52 allele impairing post-transcriptional gene silencing through SGS3 downregulation.
    Plant J., 2017. 90(3): p. 505-519
    [PMID:28207953]
  5. Elmayan T, et al.
    Arabidopsis mutants impaired in cosuppression.
    Plant Cell, 1998. 10(10): p. 1747-58
    [PMID:9761800]