PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009796096.1
Organism
Nicotiana sylvestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family C2H2
Protein Properties Length: 376aa    MW: 41866.4 Da    PI: 7.0562
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009796096.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2201.9e-06154175223
                     EETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2   2 kCpdCgksFsrksnLkrHirtH 23 
                      C  Cgk F+r  nL+ H+r H
  XP_009796096.1 154 FCDFCGKGFKRDANLRMHMRAH 175
                     6*******************99 PP
2zf-C2H211.70.00081239262123
                     EEETTTT.EEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCpdCg.ksFsrksnLkrHirtH 23 
                     y+C+ C+ ksFs   +Lk+H++ +
  XP_009796096.1 239 YSCTRCNkKSFSVLADLKSHLKHC 262
                     99*******************977 PP
3zf-C2H211.80.00075270286521
                     TTTEEESSHHHHHHHHH CS
         zf-C2H2   5 dCgksFsrksnLkrHir 21 
                      Cg+sFsrk+ L  H+ 
  XP_009796096.1 270 SCGTSFSRKDKLFGHMA 286
                     5**************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576674.85E-6150176No hitNo description
PROSITE profilePS5015712.092153180IPR007087Zinc finger, C2H2
SMARTSM003550.0024153175IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.605.7E-6153175IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280155175IPR007087Zinc finger, C2H2
SMARTSM00355150201234IPR015880Zinc finger, C2H2-like
SMARTSM0035514239261IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.600.001261286IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM00355210267291IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 376 aa     Download sequence    Send to blast
MSFFGDLRHT PAKTKPPLTT MSAAPMIGDG PRAPLLNLSA VQARMDTLQK FLSDSVNSNT  60
LLGQHQMNMV SDEITYAIHQ IIVNGAALLS STQSPNNSPH PPELKINPKS SHKRTFSEFD  120
RRGSEMDVLE EEDGGDWEII ELDAVELLAE HIHFCDFCGK GFKRDANLRM HMRAHGNQYK  180
TPEALAKPDK CIESSSKNRR FSCPFVGCCR NKSHSKFRPL KSAICVKNHF KRSHCPKMYS  240
CTRCNKKSFS VLADLKSHLK HCGETKWKCS CGTSFSRKDK LFGHMALFEG HMPAIEPEEE  300
AKPPAAAAVE DDVEMDVSRG SDNGFLDIRT GSDNGFLDRL MLDGLESIDS YCFQDLLGSS  360
SPSGLNTVPD TNEWFS
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269|PubMed:17535918, ECO:0000269|PubMed:18826429, ECO:0000269|PubMed:19321711, ECO:0000269|PubMed:23935008}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269|PubMed:17535918}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGQ2612441e-133GQ261244.1 Solanum lycopersicum cultivar Rio Grande PtoR Hop-interacting protein THI038 mRNA, complete cds.
GenBankHG9755161e-133HG975516.1 Solanum lycopersicum chromosome ch04, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009796096.10.0PREDICTED: protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
SwissprotQ9C8N51e-80STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBLA0A1U7Y2C00.0A0A1U7Y2C0_NICSY; protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
STRINGXP_009796096.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA100002126
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34370.29e-71C2H2 family protein
Publications ? help Back to Top
  1. Kobayashi Y, et al.
    Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions.
    Plant Physiol., 2013. 163(1): p. 180-92
    [PMID:23839867]
  2. Yokosho K,Yamaji N,Ma JF
    Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench).
    Plant Cell Physiol., 2014. 55(12): p. 2077-91
    [PMID:25273892]
  3. Geng X, et al.
    LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.
    Plant J., 2017. 90(3): p. 491-504
    [PMID:28181322]
  4. Balzergue C, et al.
    Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation.
    Nat Commun, 2017. 8: p. 15300
    [PMID:28504266]
  5. Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A
    Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation.
    Front Plant Sci, 2017. 8: p. 822
    [PMID:28567051]
  6. Jiang F, et al.
    Identification and characterization of suppressor mutants of stop1.
    BMC Plant Biol., 2017. 17(1): p. 128
    [PMID:28738784]
  7. Daspute AA, et al.
    Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
    Front Plant Sci, 2017. 8: p. 1358
    [PMID:28848571]
  8. Sharma A,Wai CM,Ming R,Yu Q
    Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis.
    Genome Biol Evol, 2017. 9(9): p. 2170-2190
    [PMID:28922793]
  9. Zhang Y, et al.
    The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 118
    [PMID:29491872]