PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009778533.1
Organism
Nicotiana sylvestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family HD-ZIP
Protein Properties Length: 717aa    MW: 79185.1 Da    PI: 6.8135
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009778533.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox603.8e-192677556
                    SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox  5 ttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                    +++t++q+++Le++F+++++p++++r +L++ lgL  rq+k+WFqNrR++ k
  XP_009778533.1 26 HRHTAHQIQRLEAVFKECPHPDEKSRLQLSRDLGLAPRQIKFWFQNRRTQLK 77
                    689*********************************************9987 PP
2START1701.6e-532234482206
                     HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetl 82 
                     +a   ++el+++ + +ep+W+ks     + ++ d + q+f+++++       ++ea+r+sgvv+m+   lv+ ++d + +W e ++    ka ++
  XP_009778533.1 223 IAGNSMEELIRLLQTNEPLWTKSTtdgrDVLELDSYNQIFPRANSslknsnVRVEASRDSGVVIMNGLALVNMFMDAN-KWVEFFPtivsKARII 316
                     567899*******************999999*********99999****999**************************.**************** PP

                     EEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-E CS
           START  83 evissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehv 170
                     evis g      ++lqlm+ e+q+lsplvp R + f+R ++q  +g+w+ivdvS d  q+++  ss+  +++lpSg+li++++ng+skvtwvehv
  XP_009778533.1 317 EVISCGvmggrsSTLQLMYEEMQVLSPLVPtRQSFFLRLCQQIDQGSWAIVDVSYDIIQENQYPSSSCMVHRLPSGCLIQDMPNGYSKVTWVEHV 411
                     ******************************************************9999999886667779************************* PP

                     E--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
           START 171 dlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                     +++++   h l+r l++sg+a+ga +w+  lqr+ce+
  XP_009778533.1 412 EVEEKGLiHKLYRDLIHSGMAFGAERWLGSLQRLCER 448
                     **987555***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.2E-20873IPR009057Homeodomain-like
SuperFamilySSF466897.52E-19879IPR009057Homeodomain-like
PROSITE profilePS5007117.2651979IPR001356Homeobox domain
SMARTSM003891.9E-182083IPR001356Homeobox domain
CDDcd000865.66E-182180No hitNo description
PfamPF000469.1E-172677IPR001356Homeobox domain
PROSITE patternPS0002705477IPR017970Homeobox, conserved site
PROSITE profilePS5084846.803213451IPR002913START domain
SuperFamilySSF559617.99E-36214450No hitNo description
CDDcd088752.56E-110217447No hitNo description
SMARTSM002342.3E-44222448IPR002913START domain
PfamPF018521.8E-45223448IPR002913START domain
Gene3DG3DSA:3.30.530.201.2E-5225258IPR023393START-like domain
Gene3DG3DSA:3.30.530.201.2E-5331438IPR023393START-like domain
SuperFamilySSF559618.79E-20469682No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 717 aa     Download sequence    Send to blast
MEYGGVTSSS GGGDASETHR KKKRFHRHTA HQIQRLEAVF KECPHPDEKS RLQLSRDLGL  60
APRQIKFWFQ NRRTQLKSQH ERADNCALRA ENDRIRCENI AIREAIKNVI CPSCGGPPVT  120
EDSYFDEQKL RMENMQLKEE LDKISSIAAK YIGRPISQLP PVQPIHLSSL NLMSMSSFGG  180
IGLTGPSLYL DLLPGSSMSS TIPSLPFPTL NISDMDKSLM ADIAGNSMEE LIRLLQTNEP  240
LWTKSTTDGR DVLELDSYNQ IFPRANSSLK NSNVRVEASR DSGVVIMNGL ALVNMFMDAN  300
KWVEFFPTIV SKARIIEVIS CGVMGGRSST LQLMYEEMQV LSPLVPTRQS FFLRLCQQID  360
QGSWAIVDVS YDIIQENQYP SSSCMVHRLP SGCLIQDMPN GYSKVTWVEH VEVEEKGLIH  420
KLYRDLIHSG MAFGAERWLG SLQRLCERYA CLMVSGKSSR ELGGVIPSPE GKKSMMKLAQ  480
RMVSNFCASI NPSNGHQWNA ISGLDEFEVR ATLQKSTDPG QPNGIIISAA STIWLPVPSQ  540
HVFNFLRDER TRPQWDVLSN QNPVQEVAHI ANGSHPGNCI SVLRAYNTSQ NNMLILQESC  600
IDSSGSLVIY SPVDLPSINM AMSGEDTTYI PLLPSGFTIS PDGRQGRRSN EASCSSTNNG  660
TMGDNGSEGS LVTVVFQILV SSLSSSAKMS PESVNTVNNL IGNTIHQIKA ALNCSAS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankHG9755185e-99HG975518.1 Solanum lycopersicum chromosome ch06, complete genome.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009778533.10.0PREDICTED: homeobox-leucine zipper protein HDG11-like
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A1U7WIR10.0A0A1U7WIR1_NICSY; homeobox-leucine zipper protein HDG11-like
STRINGXP_009778533.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]