PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_009775710.1

Organism

Nicotiana sylvestris

Taxonomic ID

4096

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana

Family

WRKY

Protein Properties

Length: 538aa MW: 59490.4 Da PI: 7.2239

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_009775710.1	genome	NCBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.3	4.4e-30	248	307	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt a +Cpv+k+v+r+ ed +++++tYeg+Hnh+ XP_009775710.1 248 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCIEDMSILITTYEGTHNHP 307 58*************************99**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	7.8E-31	233	307	IPR003657	WRKY domain
SuperFamily	SSF118290	5.62E-27	241	308	IPR003657	WRKY domain
PROSITE profile	PS50811	27.06	243	309	IPR003657	WRKY domain
SMART	SM00774	3.3E-36	248	308	IPR003657	WRKY domain
Pfam	PF03106	1.2E-26	249	307	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0006952	Biological Process	defense response
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 538 aa Download sequence Send to blast
MEATFRKSIN GDLVKEEKRY NKLADQSNSD KEGFFENSNV LKVGKEREVH EDNNSKSPQQ 60 KDIDSDKEDD QLQSVKADMK EVMEENQRLK MHLDRIMKDY RNLQLQFHDI VQRDAEKTNI 120 NIINTRHNEC NEAKFVSLSL GRTSTDIKKE ELSKILSKDN AKEEDNKGGL TLGLDCRIDL 180 SVKTTPTEFS TANISEENSS EEVKDEKGET WPPHKILKTM RNGEDDTQLN PSKRAKVSVR 240 VRCDAPTMND GCQWRKYGQK IAKGNPCPRA YYRCTVAPSC PVRKQVQRCI EDMSILITTY 300 EGTHNHPLSL SATSMAFTTS AAASMLLSAS SSTSESGPNL PATDTTNING LNLYLSNSSN 360 PKPFYLQNTS ISSSSSPPTI TLDLTSSSST SLLPNHNRMS SNYLPRYNSS TNILNFGSLD 420 SNPLLPVSWS NGAYPKNQEI SSLSFAKQPQ ENIFQSYLQN NISAKPTQTL LTQGTIAAAT 480 KAITSDPNFQ SALAVALTSI IGSSGGNHAG GIEEKSGQIL KVTEPFPVLF SFPSTSKK

Sequence ? help Back to Top

Protein Sequence Length: 538 aa Download sequence Send to blast

MEATFRKSIN GDLVKEEKRY NKLADQSNSD KEGFFENSNV LKVGKEREVH EDNNSKSPQQ  60
KDIDSDKEDD QLQSVKADMK EVMEENQRLK MHLDRIMKDY RNLQLQFHDI VQRDAEKTNI  120
NIINTRHNEC NEAKFVSLSL GRTSTDIKKE ELSKILSKDN AKEEDNKGGL TLGLDCRIDL  180
SVKTTPTEFS TANISEENSS EEVKDEKGET WPPHKILKTM RNGEDDTQLN PSKRAKVSVR  240
VRCDAPTMND GCQWRKYGQK IAKGNPCPRA YYRCTVAPSC PVRKQVQRCI EDMSILITTY  300
EGTHNHPLSL SATSMAFTTS AAASMLLSAS SSTSESGPNL PATDTTNING LNLYLSNSSN  360
PKPFYLQNTS ISSSSSPPTI TLDLTSSSST SLLPNHNRMS SNYLPRYNSS TNILNFGSLD  420
SNPLLPVSWS NGAYPKNQEI SSLSFAKQPQ ENIFQSYLQN NISAKPTQTL LTQGTIAAAT  480
KAITSDPNFQ SALAVALTSI IGSSGGNHAG GIEEKSGQIL KVTEPFPVLF SFPSTSKK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	2e-19	248	308	14	73	WRKY transcription factor 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009775710.1	0.0	PREDICTED: probable WRKY transcription factor 72
Swissprot	A0A3Q7GFB5	0.0	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A1U7WN69	0.0	A0A1U7WN69_NICSY; probable WRKY transcription factor 72
STRING	XP_009775710.1	0.0	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1945	24	64

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	3e-63	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]