PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009768533.1
Organism
Nicotiana sylvestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family WRKY
Protein Properties Length: 464aa    MW: 51319.1 Da    PI: 7.3396
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009768533.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY93.71.3e-29225280359
                     -SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   3 DgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                     DgynWrKYG K+vk se+prsYY+Ct  +C v+kkvers  d++++eitY+g+Hnhe
  XP_009768533.1 225 DGYNWRKYGEKKVKASECPRSYYKCTNLKCLVRKKVERSV-DGHITEITYNGRHNHE 280
                     9***************************************.***************7 PP
2WRKY106.21.6e-33395453159
                     ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
            WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                     ldDgy+WrKYGqK+vkg+++prsYYrCt++gC+v+k+ver+++dpk v++tYeg+Hnh+
  XP_009768533.1 395 LDDGYKWRKYGQKVVKGNQHPRSYYRCTYPGCNVRKQVERASTDPKSVITTYEGKHNHD 453
                     59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.1E-25220282IPR003657WRKY domain
SuperFamilySSF1182907.19E-23222282IPR003657WRKY domain
SMARTSM007742.8E-31223281IPR003657WRKY domain
PROSITE profilePS5081122.974225282IPR003657WRKY domain
PfamPF031061.3E-21225280IPR003657WRKY domain
Gene3DG3DSA:2.20.25.804.1E-36381455IPR003657WRKY domain
SuperFamilySSF1182908.89E-30387455IPR003657WRKY domain
PROSITE profilePS5081135.944390455IPR003657WRKY domain
SMARTSM007743.7E-39395454IPR003657WRKY domain
PfamPF031061.9E-26396453IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 464 aa     Download sequence    Send to blast
MGETGGASAM SFPALTIPPR PSFESFLSNL PSFSPGPMSL VSSFFSDQSP DSSDYPSFSQ  60
LLAGAMASPL AKQDNSGEGS QKNSGYKQNR PMGLVLAQSP LFMIPPGLSP SGLLNSPGFL  120
SPLQSPFGMS HQQVLAHVTA QAAFSNSYMQ MQAEDQCSSQ AASAEALGHE LTTELEETSL  180
QLKEPSQTRM DSEPSDKPGK KFELQEFSQS ENKPSFVAFE KPACDGYNWR KYGEKKVKAS  240
ECPRSYYKCT NLKCLVRKKV ERSVDGHITE ITYNGRHNHE LPQPNKQRKD GSALDGSDCS  300
EVRPDTRTHD WPVKNNSSDG SSHTRSDQVS NQMVSELLVK SECDEIKNIL VAVDEGHDEP  360
NAKRMKTAVE TLASSHGTVA ESKIVLQTRS EVDFLDDGYK WRKYGQKVVK GNQHPRSYYR  420
CTYPGCNVRK QVERASTDPK SVITTYEGKH NHDIPTLRNR NSQR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-36225455877Probable WRKY transcription factor 4
2lex_A2e-36225455877Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB7111360.0AB711136.1 Nicotiana benthamiana NbWRKY15 mRNA for transcription factor, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009768533.10.0PREDICTED: probable WRKY transcription factor 3
RefseqXP_016436720.10.0PREDICTED: probable WRKY transcription factor 3
SwissprotQ9XI901e-125WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A1S3X9V80.0A0A1S3X9V8_TOBAC; probable WRKY transcription factor 3
TrEMBLA0A1U7VQ480.0A0A1U7VQ48_NICSY; probable WRKY transcription factor 3
STRINGXP_009768533.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA43142344
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.11e-116WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]