PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_009759718.1
Organism
Nicotiana sylvestris
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family TALE
Protein Properties Length: 315aa    MW: 36150.3 Da    PI: 4.6186
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_009759718.1genomeNCBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox26.31.3e-082592922255
                     SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
        Homeobox  22 nrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                      +yp++ ++  LA+++gL+ +q+ +WF N+R ++
  XP_009759718.1 259 WPYPTEGDKNSLAESTGLDPKQINNWFINQRKRH 292
                     58*****************************885 PP
2ELK29.71.5e-10212233122
             ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                     ELK +LlrK++++L+sLk EFs
  XP_009759718.1 212 ELKGRLLRKFGSHLSSLKLEFS 233
                     9********************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012555.0E-2086130IPR005540KNOX1
PfamPF037906.5E-2288129IPR005540KNOX1
SMARTSM012562.7E-26136187IPR005541KNOX2
PfamPF037911.2E-24139186IPR005541KNOX2
SMARTSM011881.7E-5212233IPR005539ELK domain
PfamPF037895.9E-7212233IPR005539ELK domain
PROSITE profilePS512139.83212232IPR005539ELK domain
PROSITE profilePS5007112.73232295IPR001356Homeobox domain
SuperFamilySSF466899.41E-20233306IPR009057Homeodomain-like
SMARTSM003892.7E-13234299IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.602.0E-28237296IPR009057Homeodomain-like
CDDcd000868.97E-12244296No hitNo description
PfamPF059201.7E-17252291IPR008422Homeobox KN domain
PROSITE patternPS000270270293IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 315 aa     Download sequence    Send to blast
MDEEMYGFHS TSEYADKALM SPENLIMETE YNMTYHNYNT LTTPPMMFGS DDVQLSSEAA  60
NSENHQIRGS CSRRDDTEDD DEDASNIIKA KIVSHPYYPK LLRAYIDCQK VGAPPDIATV  120
LEEIRQQNDF RKANATSICI GADPELDEFM ETYCDILVKY KSDLSRPFDE ATTFLSKIEL  180
QLSNLCKDDG GVSSDEELSC GEVEGQRSED NELKGRLLRK FGSHLSSLKL EFSKKKKKGK  240
LPKEARQMLL AWWNDHYRWP YPTEGDKNSL AESTGLDPKQ INNWFINQRK RHWKPSENMQ  300
LAVMDNLSGQ FFSDD
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0257150.0AB025715.1 Nicotiana tabacum mRNA for homeobox 22, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009759718.10.0PREDICTED: homeobox protein knotted-1-like 6
SwissprotQ84JS61e-123KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLA0A1U7UZY60.0A0A1U7UZY6_NICSY; homeobox protein knotted-1-like 6
STRINGXP_009759718.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA7532480
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-113KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]