PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_018909-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family ARF
Protein Properties Length: 809aa    MW: 89336.1 Da    PI: 5.8311
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_018909-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B375.46.6e-24133234199
                    EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS
             B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 
                    f+k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++ ++W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++++
  NNU_018909-RA 133 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDNEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFI--WNEK 224
                    99*****************************8544444..48************************************************..8899 PP

                    E..EEEEE-S CS
             B3  90 felvvkvfrk 99 
                     +l+++++r+
  NNU_018909-RA 225 NQLLLGIRRA 234
                    999****997 PP
2Auxin_resp120.21.6e-39259342183
     Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                    aahaa+t+s F+++YnPras+seFv+ ++k++ka++ ++vsvGmRf+m fete+ss rr++Gt++g+sdldpvrWpnS+Wrs+k
  NNU_018909-RA 259 AAHAAATNSRFTIFYNPRASPSEFVITLAKYVKAVYhTRVSVGMRFRMLFETEESSVRRYMGTITGISDLDPVRWPNSHWRSVK 342
                    79*********************************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019361.57E-49118262IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.102.6E-42126248IPR015300DNA-binding pseudobarrel domain
CDDcd100178.85E-22132233No hitNo description
SMARTSM010192.0E-24133235IPR003340B3 DNA binding domain
PROSITE profilePS5086312.548133235IPR003340B3 DNA binding domain
PfamPF023623.1E-22133234IPR003340B3 DNA binding domain
PfamPF065072.2E-34259342IPR010525Auxin response factor
SuperFamilySSF542774.51E-7668750No hitNo description
PfamPF023094.5E-6671762IPR033389AUX/IAA domain
PROSITE profilePS5174523.509676760IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 809 aa     Download sequence    Send to blast
MCEKLSFLIC VNVAAEYFFV GEKRVLNSEL WHACAGPLVS LPAVGSRVVY FPQGHSEQVA  60
ASTNKEVDAH IPNYPSLPPQ LICQLHNVTM HADVETDEVY AQMTLQPLSP EEQKEPYLPT  120
ELGTPSKQPT NYFCKTLTAS DTSTHGGFSV PRRAAEKVFP PLDFSQQPPA QELIARDLHD  180
NEWKFRHIFR GQPKRHLLTT GWSVFVSAKR LVAGDSVLFI WNEKNQLLLG IRRANRPQTV  240
MPSSVLSSDS MHIGLLAAAA HAAATNSRFT IFYNPRASPS EFVITLAKYV KAVYHTRVSV  300
GMRFRMLFET EESSVRRYMG TITGISDLDP VRWPNSHWRS VKVGWDESTA GERQPRVSLW  360
EIEPLTTFPM YPSPFPLRLK RPWPPGLPSL HGMKDDDLGI NSQLMCLRGD GGDRGIQSLN  420
FQGIGVTPWM QPRLDASMLG LQTDMYQAMA AAALQEMRTV DPSKQASPSL LQFQQPQIAI  480
SSLCEQPSFA DSNGNPVTTS SVSPLHSLLG SFPQDETSQL LNLPRTTSLI PSTTWLPKRA  540
AVEPLLPSGA TQCVLPQVEQ MPQPQTNVSQ NSISLPPFPG RECSVDQEGS SDPQSHLLFG  600
VNIDSSSLLM QNGMSGLGGV GSDSDSTTMP FAASNFISST GTDFPLNPAV TTSSCLDESG  660
FLQSPENVGQ VNPPTRTFVK VHKSGSFGRS LDITRFSSYH ELRSELARLF GLEGQLEDPL  720
RSGWQLVFVD RENDVLLLGD DPWQEFVNNV WCIKILSPQE VQQMGKQGIE LLNSVPIQRL  780
SSNSCDDYVS RQDSRNLSSG ITSVGLLDY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1632236347388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF8. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024992699.10.0auxin response factor 6
SwissprotQ9ZTX80.0ARFF_ARATH; Auxin response factor 6
TrEMBLA0A0B0NBW50.0A0A0B0NBW5_GOSAR; Auxin response factor
STRINGGSMUA_Achr5P02450_0010.0(Musa acuminata)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30330.10.0auxin response factor 6
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Oh E, et al.
    Cell elongation is regulated through a central circuit of interacting transcription factors in the Arabidopsis hypocotyl.
    Elife, 2015.
    [PMID:24867218]
  3. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  4. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  5. Asahina M,Satoh S
    Molecular and physiological mechanisms regulating tissue reunion in incised plant tissues.
    J. Plant Res., 2015. 128(3): p. 381-8
    [PMID:25736731]
  6. Batista VG,Pinheiro MP,Melo Filho PA,Santos RC,Lima LM
    Temporal and tissue expression of genes involved in buds of earliness cotton cultivar.
    Genet. Mol. Res., 2015. 14(3): p. 7386-94
    [PMID:26214417]
  7. Li P, et al.
    Ca(2+) -regulated and diurnal rhythm-regulated Na(+) /Ca(2+) exchanger AtNCL affects flowering time and auxin signalling in Arabidopsis.
    Plant Cell Environ., 2016. 39(2): p. 377-92
    [PMID:26296956]
  8. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  9. Luo S, et al.
    Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 1156
    [PMID:26734051]
  10. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  11. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  12. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]