PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | NNU_011446-RA | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
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Family | E2F/DP | ||||||||
Protein Properties | Length: 406aa MW: 45148.7 Da PI: 4.9107 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.9 | 1.5e-27 | 141 | 206 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg NNU_011446-RA 141 RYDSSLGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 206 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.6E-29 | 139 | 208 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-34 | 141 | 206 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.18E-17 | 141 | 204 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 1.5E-24 | 143 | 206 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 9.42E-26 | 219 | 306 | No hit | No description |
CDD | cd14660 | 2.65E-36 | 222 | 306 | No hit | No description |
Pfam | PF16421 | 6.7E-21 | 244 | 304 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 406 aa Download sequence Send to blast |
MSGARASNRS AQPSGQILQP LKRHLPFSST KPPFVPPDDY HRFSRESRKV ADEEADAIVV 60 KSPPLKRKSE TEDCEGFNEW TTSPGYTEVV NSPLRTPVSG KGGRVYSKSK VPKHSKSGPQ 120 TPVPNAGSPS GNTLTPVGTC RYDSSLGLLT KKFINLIKHA EDGILDLNKA ADTLEVQKRR 180 IYDITNVLEG IGLIEKKLKN RIRWKGLDVS RPGEEDDDAT MLQAEVENLS MEEQRLDDRI 240 RWLFVTEEDI KGLPCFQNET LIAIKAPHGT TLEVPDPDEA VDYPQRRYRI VLRSTMGPID 300 VYLVSQFEKF EEMNSIEAPP SLPLASSSGS SENPAVAMVT EDCQGKEMEL QGHDDHRMYS 360 DPNASQDFVG GIMKIVPSDV DSDADYWLLS DAGVSITDMW KTERIT |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 6e-25 | 136 | 207 | 1 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | KR822414 | 4e-55 | KR822414.1 Barringtonia racemosa clone comp39641_c0 microsatellite sequence. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_010262959.1 | 0.0 | PREDICTED: transcription factor E2FA-like | ||||
Refseq | XP_019053996.1 | 0.0 | PREDICTED: transcription factor E2FA-like | ||||
Swissprot | Q9FNY0 | 1e-148 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A1U8Q7H7 | 0.0 | A0A1U8Q7H7_NELNU; transcription factor E2FA-like | ||||
STRING | XP_010262959.1 | 0.0 | (Nelumbo nucifera) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-145 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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