PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID NNU_009126-RA
Organism
Nelumbo nucifera
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
Family ARR-B
Protein Properties Length: 697aa    MW: 76144.8 Da    PI: 5.9747
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
NNU_009126-RAgenomeCASView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like91.38.5e-29211264155
        G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                    kpr++W+ eLH++Fv av+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  NNU_009126-RA 211 KPRVVWSVELHQQFVAAVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 264
                    79*******************.********************************8 PP
2Response_reg78.72e-26331411109
                    EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTE CS
   Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGa 94 
                    vl+vdD+p+ +++l ++l++  y ev+++d +e al ll+e++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a + ++ + + +  Ga
  NNU_009126-RA  33 VLVVDDDPTCLRILDRMLRNCLY-EVTTCDRAEVALSLLRESKtgFDIVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDGKDVVMKGVTHGA 126
                    89*********************.***************99999***********************6654.8*********************** PP

                    SEEEESS--HHHHHH CS
   Response_reg  95 kdflsKpfdpeelvk 109
                     d+l Kp+ +e++ +
  NNU_009126-RA 127 CDYLIKPVRIEAIKN 141
                    **********99976 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363924.8E-1719688IPR017053Response regulator B-type, plant
Gene3DG3DSA:3.40.50.23004.3E-4130174No hitNo description
SuperFamilySSF521725.69E-3530157IPR011006CheY-like superfamily
SMARTSM004484.7E-2931143IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011042.14232147IPR001789Signal transduction response regulator, receiver domain
PfamPF000724.0E-2333141IPR001789Signal transduction response regulator, receiver domain
CDDcd001562.62E-2734146No hitNo description
PROSITE profilePS5129411.048208267IPR017930Myb domain
SuperFamilySSF466893.76E-20208268IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.5E-30210269IPR009057Homeodomain-like
TIGRFAMsTIGR015571.0E-24211264IPR006447Myb domain, plants
PfamPF002491.0E-7213263IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 697 aa     Download sequence    Send to blast
MDNGGGSISM ANSTPTRKVA DEVSDQFPAG LRVLVVDDDP TCLRILDRML RNCLYEVTTC  60
DRAEVALSLL RESKTGFDIV ISDVHMPDMD GFKLLEHIGL EMDLPVIMMS ADDGKDVVMK  120
GVTHGACDYL IKPVRIEAIK NIWQHVVRKR RNELKELEQS GSVEDGDQLR KPSEDGDYAS  180
SANEGSWRNS KKRKDEEEEG EERDDTSTLK KPRVVWSVEL HQQFVAAVNQ LGIDKAVPKK  240
ILELMNVPGL TRENVASHLQ KYRLYLRRLN GVSQHQSGLN TPFMGPQDAN FGPMSSLDGL  300
DLQALAVSGQ LAPQSLATLQ AGGFGRSTAN TGISMPLVDQ RNIFSSDTSK LQFGAMPQSQ  360
SSGGKQVNLL YGLPTNMEPK QLTPLHQSVQ SFGTMGLHAS DGALSFPVTS LRTSSTDHVD  420
GVHINQSSSL MMHIAPSGTK SQLLNDILGN RTSGLQTGQK IFSSEVAGQV VGRNGIILNG  480
RGATYNPVSQ AFPMADFPIN HIVELSGNGF PLGSSTASST LTSTGMFQGG SMDIKGPRGF  540
PPSYDVLNEI LQGKPHDWNP QNMGIIFETS QPINSIQGKL DLAPSVLGNQ AFASSQKFGS  600
NRTTSVIGKA MVSQREENEH GKIEHSVQHP INNNPLVNNA FRIKHETMHD FSSDNLLLPP  660
HYVHDDLMRT LLKQQEGIGS LENEYNFDGY TMDNVPV
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A5e-22210270464ARR10-B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010259415.10.0PREDICTED: two-component response regulator ARR2-like isoform X2
SwissprotQ9ZWJ90.0ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A1U7ZZV20.0A0A1U7ZZV2_NELNU; two-component response regulator ARR2-like isoform X2
STRINGXP_010259414.10.0(Nelumbo nucifera)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16110.11e-175response regulator 2
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]