PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | NNU_002573-RA | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Proteales; Nelumbonaceae; Nelumbo
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Family | E2F/DP | ||||||||
Protein Properties | Length: 466aa MW: 51611.5 Da PI: 4.6906 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 86.6 | 1.8e-27 | 142 | 207 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+irwkg NNU_002573-RA 142 RYDSSLGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 207 6899******************************...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 4.5E-29 | 140 | 209 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 4.44E-17 | 142 | 205 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-34 | 142 | 207 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.9E-24 | 144 | 207 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
CDD | cd14660 | 9.39E-49 | 218 | 324 | No hit | No description |
SuperFamily | SSF144074 | 1.83E-34 | 219 | 324 | No hit | No description |
Pfam | PF16421 | 7.3E-34 | 223 | 322 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 466 aa Download sequence Send to blast |
MSGARASNRS AQPSGQILQP LKRHLPFSST KPPFVPPDDY HRFSGDNRRV ANEEAEAIVV 60 KSPPLKRKSE AEDCEGESSE WTTSPGYTEV VNSPLRTPVS GKGGRVYSKS KVPKHGRSGP 120 QTPVSNAGSP SGNTLTPVGT CRYDSSLGLL TKKFINLIKH AEDGILDLNK AADTLEVQKR 180 RIYDITNVLE GIGLIEKKLK NRIRWKGLDV SKPGEADDDV ANLQAEVENL SLKEQRLDDR 240 IREMQERLRD LSEDENNQKW LFVTEEDIKG LPCFQNETLI AIKAPHGTTL EVPDPDEAVD 300 YPQRRYRIVL RSTMGPIDVY LVSQFEEKFE EMNGVEAPQS LPLPSSSGSN ENPAAITVTE 360 DNSGREMELQ GNDAHRIYSD PNASHDFVSG IMKIVPSDVD SDADYWLLSD AGVSITDMWK 420 TEPGVEWDTV DPLHPEEFVM ADVSTPRPQT PPSGVIEVPS SNSIQR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-24 | 137 | 208 | 1 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00661 | PBM | Transfer from Pp3c1_6880 | Download |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_010246568.1 | 0.0 | PREDICTED: transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-166 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A1U7ZG99 | 0.0 | A0A1U7ZG99_NELNU; transcription factor E2FA | ||||
STRING | XP_010246568.1 | 0.0 | (Nelumbo nucifera) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-163 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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