PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf05487g01017.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family bHLH
Protein Properties Length: 516aa    MW: 57704.4 Da    PI: 7.362
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf05487g01017.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH25.62.3e-08328363444
                               HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHH CS
                       HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiL 44 
                               +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L
  Niben101Scf05487g01017.1 328 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLL 363
                               799***********************66......88888776 PP
2HLH39.97.8e-13370416455
                               HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
                       HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                               +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  Niben101Scf05487g01017.1 370 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAIAYITDLQ 416
                               799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142158.2E-4349228IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474596.28E-11323364IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088811.871324373IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.105.7E-10327364IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.85E-9327380No hitNo description
PfamPF000106.7E-6328363IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.1E-4330371IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.66366415IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.62E-13369420No hitNo description
SuperFamilySSF474593.4E-18369435IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.3E-10370416IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.7E-18370435IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.4E-15372421IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 516 aa     Download sequence    Send to blast
MGEKLFMKEE ERVIMEGVLG REAVEFFTWS ASNSMLMEFT SLRGDLGVQQ SLCKIVEGSD  60
WTYAIYWQVA KSKSGKSALI WGDGHCREAK MGQSEGGNDS EHHKMMDGNK KKLVLQKIHT  120
FFGGSEDDNI AAKLDSVSDV EVFYLTSMYY IFPFEKPSSP SQSFNSARSI WVSDVRGCLE  180
HFQSRSYLAK LARFETLVFI PLKSGVVELG SLKSIPEDQN LIQTVKTLVV VSNPPQPKAI  240
PKIFGRELSL GGSKSGPISI NFSPKVEEDL SFATDAYEVQ AALGSSQVYG NSSNGYRSDE  300
GEGKLELDER KPRKRGRKPA NGREEALNHV EAERQRREKL NQRFYALRAV VPNISKMDKA  360
SLLGREEALN HVEAERQRRE KLNQRFYALR AVVPNISKMD KASLLGDAIA YITDLQAKIR  420
VLDAEKDMVN DQQKQQAPLE IDFHQRQDDA VVRVGCPLNA HPVSRVLKTF QEHQIVAQES  480
NVSLTENGEI VHTFSIRAPG GAAENLKENL TAALSK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-28363432170Transcription factor MYC2
5gnj_B3e-28363432170Transcription factor MYC2
5gnj_E3e-28363432170Transcription factor MYC2
5gnj_F3e-28363432170Transcription factor MYC2
5gnj_G3e-28363432170Transcription factor MYC2
5gnj_I3e-28363432170Transcription factor MYC2
5gnj_M3e-28363432170Transcription factor MYC2
5gnj_N3e-28363432170Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1309317RKPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_009803066.10.0PREDICTED: transcription factor bHLH3
RefseqXP_009803067.10.0PREDICTED: transcription factor bHLH3
RefseqXP_016507862.10.0PREDICTED: transcription factor bHLH3-like
RefseqXP_016507863.10.0PREDICTED: transcription factor bHLH3-like
SwissprotA0A3Q7H2160.0MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A1S4D3F00.0A0A1S4D3F0_TOBAC; transcription factor bHLH3-like
TrEMBLA0A1U7YG330.0A0A1U7YG33_NICSY; transcription factor bHLH3
STRINGXP_009803066.10.0(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA66692433
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-156bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]