PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf01774g10021.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family AP2
Protein Properties Length: 647aa    MW: 71234.8 Da    PI: 7.5577
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf01774g10021.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2392e-12307363155
                       AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng.krkrfslgkfgtaeeAakaaiaarkkleg 55 
                               s+y+GV++++++gr++A+++d  ++  g  rk  + g ++ +e+Aa+a++ a++k++g
  Niben101Scf01774g10021.1 307 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqTRKGRQ-GGYDMEEKAARAYDLAALKYWG 363
                               78*******************77776664346655.77******************98 PP
2AP245.32.2e-14408457355
                       AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                               y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  Niben101Scf01774g10021.1 408 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDVAAIKFRG 457
                               9***************988532...5************************997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000185.01E-19307371No hitNo description
SuperFamilySSF541712.16E-14307373IPR016177DNA-binding domain
PfamPF008471.2E-9307363IPR001471AP2/ERF domain
PROSITE profilePS5103217.359308371IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.4E-12308372IPR001471AP2/ERF domain
SMARTSM003801.6E-22308377IPR001471AP2/ERF domain
PRINTSPR003673.1E-6309320IPR001471AP2/ERF domain
SuperFamilySSF541719.15E-18406467IPR016177DNA-binding domain
CDDcd000182.55E-25406467No hitNo description
PROSITE profilePS5103219.282407465IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.5E-18407465IPR001471AP2/ERF domain
SMARTSM003804.9E-34407471IPR001471AP2/ERF domain
PfamPF008471.0E-9408457IPR001471AP2/ERF domain
PRINTSPR003673.1E-6447467IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 647 aa     Download sequence    Send to blast
MKMKSMNDDN NNWSSHRSSN NTNSNSHNDA SSNWLGFSLS PHMKMEVTSS EPQHQHHQFN  60
NQSSALAQSF YLSSSPMNVT SNTSALSYGV GENNPFGHSS LSVMPLKSDG SLCIMEALSR  120
SHADAMVQSS SSPKLEDFLG GASQYGNHER EAMALSLDSL YYHQNEGYYS PMHCHGMYQE  180
SLLDEPKPTQ ISHCDAQMTT ASGNELKSWG HYAIDQHING TCSTMVGAGG GGGTCGSGGG  240
TFGGNDLQSL SLSMNPGSQS SCVTPRQISP NELECVAIET KKRAFGKVVQ KQPVHRKSID  300
TFGQRTSQYR GVTRHRWTGR YEAHLWDNSC KKEGQTRKGR QGGYDMEEKA ARAYDLAALK  360
YWGPSTHINF PLENYQKELE DMKNMTRQEY VAHLRRKSSG FSRGASMYRG VTRHHQHGRW  420
QARIGRVAGN KDLYLGTFST QEEAAEAYDV AAIKFRGVNA VTNFDISRYD VEKIMASNTL  480
PAGELARRNK EREPIESIEY NTNGHKNEEA CIQNVNNNNG NDVTDWKMVS YQSSNPSLGN  540
YRNPSFSMAL QDLIGIDLMN SSNHAILDDQ QNKIGNHFSN ASSLVTSLGS SREASPDKSA  600
ASLVFTKPTK FAVPSTNVNA CIPSAQLRPI PVSISHLPVF AAALNDA
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_019239081.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-152ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A1J6KQ500.0A0A1J6KQ50_NICAT; Ap2-like ethylene-responsive transcription factor ant
STRINGXP_009610222.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20742460
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-153AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]