PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Niben101Scf01563g00012.1
Organism
Nicotiana benthamiana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae; Nicotiana
Family MYB
Protein Properties Length: 320aa    MW: 36761.9 Da    PI: 5.4995
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Niben101Scf01563g00012.1genomeBTI-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding41.92.3e-134388146
                              TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
           Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46
                              +g+W +eEd+ l++ vk++G+++W++I ++  + Rt+k+c++rw +
  Niben101Scf01563g00012.1 43 KGPWKAEEDQVLLNHVKKYGPRDWSSIRSKGLLQRTGKSCRLRWVN 88
                              79*************************8887799**********87 PP
2Myb_DNA-binding452.5e-1499138344
                               SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS
           Myb_DNA-binding   3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 
                               ++++eE+   +++ +q+G++ W++Ia +++ gRt++++k++w
  Niben101Scf01563g00012.1  99 KFSEEEERTVIELQAQFGNK-WARIATYLP-GRTDNDVKNFW 138
                               89******************.*********.*********** PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129420.8143894IPR017930Myb domain
Gene3DG3DSA:1.10.10.604.3E-213891IPR009057Homeodomain-like
SuperFamilySSF466892.37E-2841138IPR009057Homeodomain-like
SMARTSM007174.2E-114292IPR001005SANT/Myb domain
CDDcd001679.40E-114590No hitNo description
PfamPF139214.1E-124696No hitNo description
Gene3DG3DSA:1.10.10.601.7E-1892144IPR009057Homeodomain-like
PROSITE profilePS5129418.42895146IPR017930Myb domain
SMARTSM007174.1E-1396144IPR001005SANT/Myb domain
CDDcd001671.54E-1099138No hitNo description
PfamPF002495.4E-1399138IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0048235Biological Processpollen sperm cell differentiation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 320 aa     Download sequence    Send to blast
MSIEFADIKH ERNFVELNME GRRSSSYNSS RYGLEDNEDE IKKGPWKAEE DQVLLNHVKK  60
YGPRDWSSIR SKGLLQRTGK SCRLRWVNKL RPNLKNGVKF SEEEERTVIE LQAQFGNKWA  120
RIATYLPGRT DNDVKNFWSS RQKRLARILR TSAPQLAKPH NNNNNNISQN NVPKFSSSTD  180
QEESLSKSQS CSSSYFDNSH NMINMVPLSE LVNPNSIAFE SNLLQLDFTP NDNKLGIGSS  240
HIQTDFALPL ENQEFNRPDF IDVFGQFNGL DNVQVPFVER SCYDNVVKRE IDKPLTPDSF  300
VDDFPFDMFD DIGPLPSPSE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C2e-294014424126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001312780.11e-178transcription factor MYB24-like
RefseqXP_009587874.11e-178PREDICTED: transcription factor MYB24-like
SwissprotA0A178VEK72e-79DUO1_ARATH; Transcription factor DUO1
TrEMBLQ8H0H31e-177Q8H0H3_TOBAC; Uncharacterized protein B25
STRINGXP_009587874.11e-178(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA42072342
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.11e-72MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]