PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr6g029180.1
Common NameMTR_6g029180
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family ERF
Protein Properties Length: 314aa    MW: 34658.1 Da    PI: 6.2996
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr6g029180.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP253.27.4e-173281255
              AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                     ++ GVr+++ +gr+vAeI+d ++   + r +lg+f taeeAa+a+++a+  l+g
  Medtr6g029180.1 32 KFVGVRQRP-SGRYVAEIKDTTQ---NIRMWLGTFETAEEAARAYDEAATLLRG 81
                     799******.7*********433...5**********************98887 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103218.6763289IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.102.4E-263289IPR001471AP2/ERF domain
PfamPF008471.8E-113281IPR001471AP2/ERF domain
SMARTSM003808.6E-343296IPR001471AP2/ERF domain
SuperFamilySSF541714.05E-183289IPR016177DNA-binding domain
CDDcd000185.91E-293288No hitNo description
PRINTSPR003674.9E-73344IPR001471AP2/ERF domain
PRINTSPR003674.9E-75571IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 314 aa     Download sequence    Send to blast
MEIQFDEPKK SLRPKKVNKF KGRNKKSETR DKFVGVRQRP SGRYVAEIKD TTQNIRMWLG  60
TFETAEEAAR AYDEAATLLR GSKTRTNFVT HVSYDSPLAS RIRHLLNNRK KGTKQQDMNG  120
ISSTTSHADT TNDTTSDGST SSTTNCIGTA SGAINSTSAS GVTSTSTNIS TSASGVASTS  180
TDISTNSSNT NVNDKSESLL SSSTTMQKPN LFEDAYRPDM SNLTNEYESS SYKSNVSWDF  240
GPIFDNFPFD QWLDMTNNDG LLCDMVDKGV SEFERMKVER QISASLYAIN GVQEYMKNVQ  300
DCNEAQWNLS PLC*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A6e-163388359ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.11280.0root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, root hairs and leaves (PubMed:17827349). Expressed in root epidermis and root hairs (PubMed:23077241). {ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs). Binds to the GCC box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Involved in early stages of root nodule development. Functions redundantly with ERN1. Is essential with ERN1 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr6g029180.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by Nod factors in root hairs. {ECO:0000269|PubMed:17827349}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1568270.0AC156827.4 Medicago truncatula chromosome 6 clone mth2-15c17, complete sequence.
GenBankEU0388030.0EU038803.2 Medicago truncatula ERN2 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003618945.10.0ethylene-responsive transcription factor RAP2-11
SwissprotA9Y0K80.0ERN2_MEDTR; Ethylene-responsive transcription factor ERN2
TrEMBLA0A396HIQ50.0A0A396HIQ5_MEDTR; Putative transcription factor AP2-EREBP family
STRINGAES751630.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33413069
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.12e-23related to AP2 11
Publications ? help Back to Top
  1. Andriankaja A, et al.
    AP2-ERF transcription factors mediate Nod factor dependent Mt ENOD11 activation in root hairs via a novel cis-regulatory motif.
    Plant Cell, 2007. 19(9): p. 2866-85
    [PMID:17827349]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  4. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  5. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]