PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr5g033720.1
Common NameMTR_5g033720
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family TALE
Protein Properties Length: 317aa    MW: 35727.2 Da    PI: 4.7939
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr5g033720.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox30.65.6e-102592932155
                      HSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
         Homeobox  21 knrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                      k +yp+++++ eLAk++gL+++q+ +WF N+R ++
  Medtr5g033720.1 259 KWPYPTEADKIELAKSTGLDQKQINNWFINQRKRH 293
                      569*****************************885 PP
2ELK31.92.9e-11213234122
              ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                      ELK++LlrK+++++g+Lk EFs
  Medtr5g033720.1 213 ELKDRLLRKFGSHIGTLKLEFS 234
                      9********************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012551.0E-2270114IPR005540KNOX1
PfamPF037901.4E-2272113IPR005540KNOX1
SMARTSM012561.7E-27121172IPR005541KNOX2
PfamPF037911.2E-25125171IPR005541KNOX2
PROSITE profilePS512139.83213233IPR005539ELK domain
SMARTSM011886.5E-6213234IPR005539ELK domain
PfamPF037893.6E-8213234IPR005539ELK domain
PROSITE profilePS5007113.281233296IPR001356Homeobox domain
SuperFamilySSF466899.41E-20234307IPR009057Homeodomain-like
SMARTSM003892.3E-14235300IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.601.9E-28238297IPR009057Homeodomain-like
CDDcd000861.49E-14245297No hitNo description
PfamPF059203.8E-18253292IPR008422Homeobox KN domain
PROSITE patternPS000270271294IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010073Biological Processmeristem maintenance
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 317 aa     Download sequence    Send to blast
MEEMYGVPTT VEYGDKSLMT PENLIFPADY NSFLMSTTSS TNRIPMFGSD DIFTAAEPSS  60
AGIQDDVASN IMKAKIASHP YYPRLLQAYI DCQKVGAPPE IASLLEEIRR ENDMCKRDVV  120
VSTCFGADPE LDEFMESYCD MLVKYKSDLT RPFDEATTFL NKIETQLSHL CTGGAAAASL  180
PTASDDGGAS SDEDLSTGDG DVQDGQSRGE DRELKDRLLR KFGSHIGTLK LEFSKKKKKG  240
KLPKEARQTL LQWWNVHYKW PYPTEADKIE LAKSTGLDQK QINNWFINQR KRHWKPSENM  300
QFSMMENFTG RFLTEE*
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: First detected in torpedo stage embryos at the boundaries between the presumptive SAM and the cotyledons. Later expressed between the cotyledons and the meristem, and between the cotyledons. In seedlings, localised in stipules and at the boundaries between the SAM and the emerging primordia. Expressed at the site of lateral roots. {ECO:0000269|PubMed:16798887}.
UniprotTISSUE SPECIFICITY: Expressed predominantly in shoot apices of seedlings, and, to a lower extent, in rosette leaves. {ECO:0000269|PubMed:11311158}.
Functional Description ? help Back to Top
Source Description
UniProtPlays a role in meristem function. Contributes to the shoot apical meristem (SAM) maintenance and organ separation by controlling boundary establishment in embryo in a CUC1, CUC2 and STM-dependent manner. Involved in maintaining cells in an undifferentiated, meristematic state. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:16798887}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr5g033720.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Seems to be repressed by AS2 and AS1 but induced by STM, CUC1 and CUC2. {ECO:0000269|PubMed:11311158, ECO:0000269|PubMed:16798887}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT1472300.0BT147230.1 Medicago truncatula clone JCVI-FLMt-16N5 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003613183.10.0homeobox protein knotted-1-like 6
SwissprotQ84JS61e-145KNAT6_ARATH; Homeobox protein knotted-1-like 6
TrEMBLG7K0600.0G7K060_MEDTR; Homeobox knotted-like protein
STRINGAES961410.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF62034125
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G23380.11e-134KNOTTED1-like homeobox gene 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  3. Khan M, et al.
    Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
    Plant Physiol., 2015. 169(3): p. 2166-86
    [PMID:26417006]