PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g107970.1
Common NameMTR_4g107970
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family WRKY
Protein Properties Length: 614aa    MW: 66869.6 Da    PI: 6.5718
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g107970.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY94.76.4e-30254313159
                      ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
             WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                      ++Dg++WrKYGqK  kg+++pr+YYrCt a +Cpv+k+v+r+ ed +++++tYeg+Hnh+
  Medtr4g107970.1 254 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCVEDMSILITTYEGTHNHS 313
                      58***************************99****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.802.7E-31239315IPR003657WRKY domain
SuperFamilySSF1182905.1E-27247315IPR003657WRKY domain
PROSITE profilePS5081127.933249315IPR003657WRKY domain
SMARTSM007741.1E-35254314IPR003657WRKY domain
PfamPF031063.8E-26255312IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 614 aa     Download sequence    Send to blast
MECSSGRSGD GDSGLKDDKR SEHSTGDDHE SHHHKKEIIA EEAPIASTER SIEAGPSTIS  60
SPKNDKVDEQ LETTKAQMGE VREENQRLKM CLNKIMTEYR ALEMQFNNMV KQETKKNNDN  120
NHEEMNAESD LVSLSLGRVP SNNIPKNDQE KVNKVSKLAL NNDEEFNKEE LSLGLECKFE  180
TSKSGSTTEG LPNIPSPVNS SEVVPIKNDE VVETWPPSKT LNKTMRDAED EVAQQTPAKK  240
ARVCVRARCD TPTMNDGCQW RKYGQKIAKG NPCPRAYYRC TVAPSCPVRK QVQRCVEDMS  300
ILITTYEGTH NHSLPLSATA MASTTSAAAS MLLSGSSTSN SGSMPSAQTN NNLHGLNFYL  360
PDGTKSNQLY LSNPALSSQH SHPTITLDLT SNPSNSSTSS PFVRFNSSYN NNNQLPRYPS  420
STLSFSSPES NPMHWNSFLN YATTQNQPYS NNRNNNNLST LNFGRQNTME SIYQTYMQKN  480
NNSSNISQHV GLQDSTISAA TKAITADPTF QSALAAALSS LIGNTTNQGN QNQSAGENLS  540
QKMKWAEMFQ VSSTSLPSSS SKVNGCASSF LNKTAPVNNT QNGSLMLLSP SLPFSATKSA  600
STSPGGDNSD NTN*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A7e-21241315174WRKY transcription factor 1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Mtr.64880.0root
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, trichomes and fruits. {ECO:0000269|PubMed:24884371}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269|PubMed:20409007, ECO:0000269|PubMed:24884371}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g107970.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269|PubMed:20409007}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1227260.0AC122726.22 Medicago truncatula chromosome 8 clone mth2-23o24, complete sequence.
GenBankAC1467760.0AC146776.43 Medicago truncatula chromosome 8 clone mth2-125i24, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003609019.10.0probable WRKY transcription factor 72
SwissprotA0A3Q7GFB51e-124WK72A_SOLLC; WRKY transcription factor 72A
TrEMBLG7JPY70.0G7JPY7_MEDTR; Putative transcription factor WRKY family
STRINGAES912160.0(Medicago truncatula)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF65034134
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G15130.11e-69WRKY DNA-binding protein 72
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  3. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]