PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr4g077797.1
Common NameMTR_4g077797
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family E2F/DP
Protein Properties Length: 343aa    MW: 37563.8 Da    PI: 5.2945
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr4g077797.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP87.69.2e-2889171271
          E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwkg 71 
                      ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+a+++i+k +k+ei+wkg
  Medtr4g077797.1  89 NGRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfsdpsngglspdqqqyDEKNIRRRVYDALNVLMAMDIISK-DKKEIQWKG 171
                      789********...*****999*******************************************************.*******98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094041.1E-1262342IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.101.1E-4684177IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-3488171IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.9E-2590171IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.93E-2291172IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd144584.00E-43176279IPR014889Transcription factor DP, C-terminal
SMARTSM011386.6E-67178340IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440742.62E-41178285No hitNo description
PfamPF087815.7E-40179291IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007049Biological Processcell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 343 aa     Download sequence    Send to blast
MGTQPHQSSV DEEDEELMGC GTTISGQSGS TSRSAGLPSS RSEQTTGTAA GDNAALKLNH  60
LDIQDDDAAS QAVVATKKKK RRAVGGDKNG RGLRQFSMKV CEKVESKGRT TYNEVADELV  120
AEFSDPSNGG LSPDQQQYDE KNIRRRVYDA LNVLMAMDII SKDKKEIQWK GLPRTSLSDI  180
EELKTQRLGL RSRIERKAAY LQELEQQFVG LQNLIQRNEQ LYSSGNPPSG GVSLPFILVQ  240
TRPHATVEVE ISEDMQLVHF DFNSSPFELH DDNYVLKAMD FGGGERPQSD NVTHNIADGG  300
EGSSMSGMYQ SQVPQSVSNM LVRPPTSPPL PGILKARVKQ EH*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B3e-3682176193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17681KKKKRR
27781KKKRR
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the whole cell cycle. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr4g077797.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013456629.10.0transcription factor-like protein DPB isoform X1
SwissprotQ9FNY21e-148DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A072UXQ90.0A0A072UXQ9_MEDTR; Putative transcription factor E2F-DP family
STRINGXP_004505605.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF33213366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.11e-128Transcription factor DP
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]