PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr2g093740.3
Common NameMTR_2g093740
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family ARF
Protein Properties Length: 697aa    MW: 77190.2 Da    PI: 8.5073
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr2g093740.3genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B373.62.3e-23168269199
                      EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSS CS
               B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrs 88 
                      f+k+lt sd++++g +++p++ ae++      + +++ s++l+ +d++g  W++++iyr++++r++lt+GW+ Fv++++L +gD v+F   + +
  Medtr2g093740.3 168 FCKTLTASDTSTHGGFSVPRRAAEDCfppldyK-QQRPSQELVAKDLHGVGWKFRHIYRGQPRRHLLTTGWSIFVSQKNLVSGDAVLFL--RGE 258
                      99****************************963.3445679************************************************..449 PP

                      EE..EEEEE-S CS
               B3  89 efelvvkvfrk 99 
                      ++el+++++r+
  Medtr2g093740.3 259 NGELRLGIRRA 269
                      9999****996 PP
2Auxin_resp119.62.4e-39294376182
       Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrl.sGtvvgvsdldpvrWpnSkWrsL 82 
                      +a+a+s ks+F+v+Y+Pras+++Fvv+++k+ k+++++v++G+Rfkm+fe+++s+err+ sG+v+g+sdldp++Wp+SkWr+L
  Medtr2g093740.3 294 VANAISAKSMFHVFYSPRASHADFVVPYQKYAKSIRNPVTIGTRFKMKFEMDESPERRCsSGIVTGMSDLDPYKWPKSKWRCL 376
                      689********************************************************9**********************9 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.22E-43164278IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.7E-39165280IPR015300DNA-binding pseudobarrel domain
CDDcd100171.22E-21166268No hitNo description
SMARTSM010198.9E-23168270IPR003340B3 DNA binding domain
PROSITE profilePS5086312.943168270IPR003340B3 DNA binding domain
PfamPF023622.8E-21168269IPR003340B3 DNA binding domain
PfamPF065072.7E-33294376IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0010050Biological Processvegetative phase change
GO:0010158Biological Processabaxial cell fate specification
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 697 aa     Download sequence    Send to blast
MEIDLNDSIT EVKKNVCSNG KCEKSVCCVC TLSSSSSPTC SSSSSTSAIV SSSYLELWHA  60
CAGPLTSLPK KGNVVVYFPQ GHLEQVASLS LFSSLEIPTY GLQPQILCRV VNVQLLANKE  120
NDEVYTQVAL LPQAELAGMC LDDKEPEGLE ADDEGNGRSP TKLASHMFCK TLTASDTSTH  180
GGFSVPRRAA EDCFPPLDYK QQRPSQELVA KDLHGVGWKF RHIYRGQPRR HLLTTGWSIF  240
VSQKNLVSGD AVLFLRGENG ELRLGIRRAA RPRNGLPESI IGNQSCSPSF LSSVANAISA  300
KSMFHVFYSP RASHADFVVP YQKYAKSIRN PVTIGTRFKM KFEMDESPER RCSSGIVTGM  360
SDLDPYKWPK SKWRCLMVRW DEDIGANHQD RVSPWEIDPS TSLPPLNIQS SRRLKKLRTG  420
LHVESPSHFI TAGDSGFMDF DESIRSSKVL QGQEKTSFMS LYYGCDTVTK QKEFDINSLR  480
HTNLASNGAR KITSSEFTRI QPSSYADFTE MNRFPRVLQA QEIYPLRSLT GKVDLNLNSW  540
GKTNVSYTKY NLHNATKLNF HSLGSEVLQN SSFPYGDIHK VGQGSSMLCS KPTNFQLGNV  600
SFNTPSSQIG ALRNEVGLSS FKIRNEQKLQ NDISAATSLD ANIRISNDEN FKEMVNPCKL  660
FGFSLSAAAE TTSQNLQNSA KRSCTKVSDD SNRVIL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldy_A1e-1215640222357Auxin response factor 1
4ldy_B1e-1215640222357Auxin response factor 1
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the whole plant. {ECO:0000269|PubMed:10476078}.
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. {ECO:0000269|PubMed:12036261}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr2g093740.3
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1508910.0AC150891.3 Medicago truncatula chromosome 2 clone mth2-76a9, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003597191.20.0auxin response factor 4 isoform X2
SwissprotQ9ZTX90.0ARFD_ARATH; Auxin response factor 4
TrEMBLA0A072VCZ30.0A0A072VCZ3_MEDTR; Auxin response factor
STRINGAES674420.0(Medicago truncatula)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60450.10.0auxin response factor 4
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  3. Machida C,Nakagawa A,Kojima S,Takahashi H,Machida Y
    The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis.
    Wiley Interdiscip Rev Dev Biol, 2015 Nov-Dec. 4(6): p. 655-71
    [PMID:26108442]
  4. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  5. Matsumura Y, et al.
    A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis.
    Biol Open, 2016. 5(7): p. 942-54
    [PMID:27334696]
  6. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  7. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]