PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Medtr2g090745.1
Common NameMTR_2g090745
Organism
Medicago truncatula
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago
Family C2H2
Protein Properties Length: 430aa    MW: 47952.6 Da    PI: 8.6905
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Medtr2g090745.1genomeMtView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H2157.4e-053658123
                     EEETTTTEEESSHHHHHHHHHHT CS
          zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                     ++C++C k F r  nL+ H r H
  Medtr2g090745.1 36 FVCEICLKDFQRDQNLQLHRRGH 58
                     89*******************88 PP
2zf-C2H212.40.00046112134123
                      EEETTTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                      +kC++C+k +  +s+ k H +t+
  Medtr2g090745.1 112 WKCEKCSKFYAVQSDWKAHSKTC 134
                      58*****************9998 PP
3zf-C2H210.80.0016142160523
                      TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   5 dCgksFsrksnLkrHirtH 23 
                      dCg+ Fsr++++++H   +
  Medtr2g090745.1 142 DCGTIFSRRDSFVTHRAFC 160
                      8**************8765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.601.9E-43558IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576674.89E-53558No hitNo description
PROSITE profilePS5015710.2213658IPR007087Zinc finger, C2H2
PROSITE patternPS0002803858IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.609.4E-4100133IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576674.89E-5107132No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005634Cellular Componentnucleus
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 430 aa     Download sequence    Send to blast
MDNREISNGF LHENTTNPEA EVISLSPKTL MATNRFVCEI CLKDFQRDQN LQLHRRGHNL  60
PWKLKQRTSK EIRKRVYVCP EKTCVHNHPS RALGDLTGIK KHFCRKHGEK KWKCEKCSKF  120
YAVQSDWKAH SKTCGTREYK CDCGTIFSRR DSFVTHRAFC DALAEETARI NGSTNINNSL  180
LGMGGNNIGN YNIMQNSLVP NIGTHFSSIF KPISCTNHET TNQTSRSGLS LWMSQTSHDT  240
ILANNSNLHE IHENWVFGNK FSSNNECQEL TSSISLPLVN NNIDNKDSTT STNNLVSVPS  300
LYSSQHQSQS HHQTTSANMS ATALLQKAAQ IGTTSTESLF LGSLGLRCNS PSQDHGNKFC  360
GVYGSSSVLT SSDLGSAESY ISGELSQMPS IKRRRVQNEE GVWGQTRDFL GVGGANHLPQ  420
FINRRMDLI*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C2e-35108177372Zinc finger protein JACKDAW
5b3h_F2e-35108177372Zinc finger protein JACKDAW
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1391395KRRRV
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in the ground tissue and stele cells of embryos and 2-days post-germination roots but not in the quiescent center (PubMed:17785527). Detected only in cells that perform asymmetric cell divisions (PubMed:17785527). In roots, present in cortex, endodermis, and pericycle layer (PubMed:25829440). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:25829440}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00125DAPTransfer from AT1G03840Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMedtr2g090745.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC1227281e-140AC122728.32 Medicago truncatula clone mth2-22l4, complete sequence.
GenBankCU1796971e-140CU179697.4 M.truncatula DNA sequence from clone MTH2-63I19 on chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024633339.10.0zinc finger protein MAGPIE
SwissprotQ9ZWA61e-131IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLA0A072VBM10.0A0A072VBM1_MEDTR; C2H2-like zinc finger protein, putative
STRINGXP_004487192.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF46262951
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G03840.21e-122C2H2 family protein
Publications ? help Back to Top
  1. Young ND, et al.
    The Medicago genome provides insight into the evolution of rhizobial symbioses.
    Nature, 2011. 480(7378): p. 520-4
    [PMID:22089132]
  2. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  3. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]