PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr1g100970.4

Common Name

MTR_1g100970

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

Nin-like

Protein Properties

Length: 692aa MW: 76057.1 Da PI: 6.2433

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr1g100970.4	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	91.1	8.2e-29	283	333	2	52
RWP-RK 2 ekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 ek+isle+l++yF++++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rki+++ Medtr1g100970.4 283 EKSISLEVLQRYFAGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKINKV 333 799**********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.461	272	353	IPR003035	RWP-RK domain
Pfam	PF02042	1.1E-25	286	333	IPR003035	RWP-RK domain
SuperFamily	SSF54277	3.92E-22	592	681	No hit	No description
SMART	SM00666	2.6E-25	595	678	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	2.6E-26	595	677	No hit	No description
Pfam	PF00564	7.5E-19	595	677	IPR000270	PB1 domain
PROSITE profile	PS51745	24.446	595	678	IPR000270	PB1 domain
CDD	cd06407	1.57E-33	596	677	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0010118	Biological Process	stomatal movement
GO:0010167	Biological Process	response to nitrate
GO:0042128	Biological Process	nitrate assimilation
GO:0005634	Cellular Component	nucleus
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 692 aa Download sequence Send to blast
MLLNQICNEG RQNALSEILE ILTVVCETHN LPLAQTWVPC RHRSVLAHGG GFKKSCSSFD 60 GSCMGQVCMS TTEAAAYIVD AHLWGFREAC VEHHLQQGQG VAGRAFLSQT MSFCTNITQF 120 CKTDYPLVHY ALMFGLTSCF AICLRSFHTG NDDYVLEFFL PPGITEFHEQ KTLLGSIFST 180 MKQHFQSLNI AAGVELEENG SIEIIEATDE GIRLRTESIP IAQSIKSPPR PDASPNMEDE 240 EEGVPQDPSE VRGENVGGSV DPMSTLGNKN IKKPSERKRG KTEKSISLEV LQRYFAGSLK 300 DAAKSLGVCP TTMKRICRQH GISRWPSRKI NKVNRSLSKL KRVIDSVQRA EGAFDLNSLG 360 NNQLPIVSSF PEPSTLNKSS QQGSLSNRPS EPQMKENEFD ASKVSETNLQ IVMENQLLGG 420 RKHSLEKEVI NGKGVTIQEI GKDRKRNRTR SGSSEDSTNP TSHGSCHGSP PIEIPTIKDL 480 FIPSNNEQHV VLRRSPEPGM QPTNALNSPT AHRMVDNVIA ELQEPFGGLL IEDAGSSKDL 540 RNLCPSVAEA ILEDMAPEAC GNNFPGSSHL APPKQCIDTI NNSATPFAAR KEMKTVTIKA 600 TYREDIIRFR VSLNCGIVEL KEEVSKRLKL EVGTFDIKYM DDDNEWVLIA CDADLQECMY 660 LSRSSGGSNI IRVLVHDITS NLGSSCESSG E*

Sequence ? help Back to Top

Protein Sequence Length: 692 aa Download sequence Send to blast

MLLNQICNEG RQNALSEILE ILTVVCETHN LPLAQTWVPC RHRSVLAHGG GFKKSCSSFD  60
GSCMGQVCMS TTEAAAYIVD AHLWGFREAC VEHHLQQGQG VAGRAFLSQT MSFCTNITQF  120
CKTDYPLVHY ALMFGLTSCF AICLRSFHTG NDDYVLEFFL PPGITEFHEQ KTLLGSIFST  180
MKQHFQSLNI AAGVELEENG SIEIIEATDE GIRLRTESIP IAQSIKSPPR PDASPNMEDE  240
EEGVPQDPSE VRGENVGGSV DPMSTLGNKN IKKPSERKRG KTEKSISLEV LQRYFAGSLK  300
DAAKSLGVCP TTMKRICRQH GISRWPSRKI NKVNRSLSKL KRVIDSVQRA EGAFDLNSLG  360
NNQLPIVSSF PEPSTLNKSS QQGSLSNRPS EPQMKENEFD ASKVSETNLQ IVMENQLLGG  420
RKHSLEKEVI NGKGVTIQEI GKDRKRNRTR SGSSEDSTNP TSHGSCHGSP PIEIPTIKDL  480
FIPSNNEQHV VLRRSPEPGM QPTNALNSPT AHRMVDNVIA ELQEPFGGLL IEDAGSSKDL  540
RNLCPSVAEA ILEDMAPEAC GNNFPGSSHL APPKQCIDTI NNSATPFAAR KEMKTVTIKA  600
TYREDIIRFR VSLNCGIVEL KEEVSKRLKL EVGTFDIKYM DDDNEWVLIA CDADLQECMY  660
LSRSSGGSNI IRVLVHDITS NLGSSCESSG E*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00449	DAP	Transfer from AT4G24020	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr1g100970.4

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC146755	0.0	AC146755.23 Medicago truncatula clone mth2-15i15, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013469658.1	0.0	protein NLP6 isoform X2
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A072W053	0.0	A0A072W053_MEDTR; Plant regulator RWP-RK family protein
STRING	AES62521	0.0	(Medicago truncatula)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Medtr1g100970.4
Entrez Gene	11421138

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]