PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr1g069940.1

Common Name

MTR_1g069940

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

ERF

Protein Properties

Length: 241aa MW: 27188.1 Da PI: 8.1828

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr1g069940.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	56.9	5e-18	94	144	2	55
AP2 2 gykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ykGVr+++ +g+++AeIrd + k r+++g+f+tae Aa a+++a+++ +g Medtr1g069940.1 94 SYKGVRRRP-WGKFAAEIRDsT--R-KGVRVWIGTFDTAEAAALAYDQAALSTRG 144 69*****.******32..2.24********************99887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	5.89E-19	93	154	No hit	No description
Gene3D	G3DSA:3.30.730.10	2.0E-29	94	153	IPR001471	AP2/ERF domain
Pfam	PF00847	3.0E-13	94	144	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.37E-21	94	153	IPR016177	DNA-binding domain
SMART	SM00380	2.8E-34	94	158	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.813	94	152	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.7E-10	95	106	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.7E-10	118	134	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 241 aa Download sequence Send to blast
MDFDSSFFQI QYQNLDTSFS NTSSFLESFS WEDFFSFNED NNKTLPLNQS AQIFKESSTS 60 YSNSSTSNSQ ISNESQEVSS NSTQLVQSSS PKKSYKGVRR RPWGKFAAEI RDSTRKGVRV 120 WIGTFDTAEA AALAYDQAAL STRGSMAVLN FPEHVVRESL KDMENNKSWE KDGSSPVLAL 180 KRKHTLKRKS KASNCKKTKR VEREMENNNN IVSQNVLVLE DLGSEYLDQL LSLSTYQVIC 240 *

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	2e-26	93	155	1	63	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	3e-26	95	153	15	73	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.23236	0.0	root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269\|PubMed:11950980}.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fusiarium oxysporum lycopersici), but probably not to necrotizing bacteria (Pseudomonas syringae tomato). {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr1g069940.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Ethylene induction is completely dependent on functional ETHYLENE-INSENSITIVE2 (EIN2), ETHYLENE-INSENSITIVE3 (EIN3), which is itself a transcription factor and CORONATIVE-INSENSITIVE1 (COI1) proteins. Induction by jasmonate, B.cinerea or F.oxysporum as well as the synergistic induction by ethylene and jasmonate requires EIN2 and COI1. Induction by methyl jasmonate (MeJA) is independent of JAR1. Induction by salicylic acid (SA) is dependent on NPR1 but not on PAD4. Seems not to be induced by Alternaria brassicicola. {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT149061	0.0	BT149061.1 Medicago truncatula clone JCVI-FLMt-5D5 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013468494.1	1e-176	ethylene-responsive transcription factor 1B
Swissprot	Q8LDC8	1e-48	ERF92_ARATH; Ethylene-responsive transcription factor 1B
TrEMBL	A0A072VLN1	1e-175	A0A072VLN1_MEDTR; Ethylene-responsive transcription factor 1B
STRING	XP_004495104.1	8e-84	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF15185	10	13

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G31230.1	2e-39	ethylene-responsive element binding factor 15

Link Out ? help Back to Top
Phytozome	Medtr1g069940.1
Entrez Gene	25484268

Publications ? help Back to Top
Zarate SI,Kempema LA,Walling LL Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses. Plant Physiol., 2007. 143(2): p. 866-75 [PMID:17189328] Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Vahabi K,Camehl I,Sherameti I,Oelmüller R Growth of Arabidopsis seedlings on high fungal doses of Piriformospora indica has little effect on plant performance, stress, and defense gene expression in spite of elevated jasmonic acid and jasmonic acid-isoleucine levels in the roots. Plant Signal Behav, 2013. 8(11): p. e26301 [PMID:24047645] Kim HG, et al. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiol., 2013. 163(4): p. 1776-91 [PMID:24170202] Li J,Jia H,Wang J cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots. Plant Cell Rep., 2014. 33(3): p. 447-59 [PMID:24306353] Zhong S, et al. Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20 [PMID:24599595] Kim HG, et al. GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis. FEBS Lett., 2014. 588(9): p. 1652-8 [PMID:24631536] Schellingen K, et al. Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression. BMC Plant Biol., 2014. 14: p. 214 [PMID:25082369] Ellouzi H, et al. A comparative study of the early osmotic, ionic, redox and hormonal signaling response in leaves and roots of two halophytes and a glycophyte to salinity. Planta, 2014. 240(6): p. 1299-317 [PMID:25156490] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Cheng MC,Kuo WC,Wang YM,Chen HY,Lin TP UBC18 mediates ERF1 degradation under light-dark cycles. New Phytol., 2017. 213(3): p. 1156-1167 [PMID:27787902] Timmermann T, et al. Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance. Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230 [PMID:28118091] Yu Y,Huang R Integration of Ethylene and Light Signaling Affects Hypocotyl Growth in Arabidopsis. Front Plant Sci, 2017. 8: p. 57 [PMID:28174592] Lestari R, et al. Overexpression of Hevea brasiliensis ethylene response factor HbERF-IXc5 enhances growth and tolerance to abiotic stress and affects laticifer differentiation. Plant Biotechnol. J., 2018. 16(1): p. 322-336 [PMID:28626940] Dinolfo MI,Castañares E,Stenglein SA Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways. Fungal Biol, 2017. 121(10): p. 841-848 [PMID:28889908]