PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr0939s0010.1

Common Name

MTR_0939s0010

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

ERF

Protein Properties

Length: 198aa MW: 21525.1 Da PI: 9.1615

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr0939s0010.1	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	53.6	5.5e-17	63	113	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 + y+GVr++ +g+WvAeIr+p + r r +lg+f a +Aa a+++a+++++g Medtr0939s0010.1 63 CNYRGVRQRT-WGKWVAEIREP---N-RgNRLWLGTFSNAVGAALAYDEAARAMYG 113 56***999.******8...2.359*********************987 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	1.1E-10	63	113	IPR001471	AP2/ERF domain
CDD	cd00018	8.18E-30	63	123	No hit	No description
Gene3D	G3DSA:3.30.730.10	1.0E-30	64	122	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	20.903	64	121	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.45E-20	64	121	IPR016177	DNA-binding domain
SMART	SM00380	6.8E-36	64	127	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-11	65	76	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-11	103	123	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 198 aa Download sequence Send to blast
MLVKSQNKVD GHKSLADTLA RWKEYNARLE SSGEAPKPVR KVPAKGSKKG CMKGKGGPEN 60 SRCNYRGVRQ RTWGKWVAEI REPNRGNRLW LGTFSNAVGA ALAYDEAARA MYGSCARLNF 120 PNVEVSNFSQ VESLKDSPAA DQSGFVKTTA ENTESVVSLD NTRVDAAEDI DMKDLSLSLS 180 VTVNHLEREG ESLSVSS*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	1e-17	64	121	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	2e-17	64	121	5	63	ATERF1
3gcc_A	2e-17	64	121	5	63	ATERF1
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Mtr.20682	0.0	root

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and abscisic acid-inducible transcription. {ECO:0000269\|PubMed:11798174}.
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription (By similarity). {ECO:0000250}.
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive element (DRE). Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. {ECO:0000269\|PubMed:12609047}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr0939s0010.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By high-salt and drought stresses. {ECO:0000269\|PubMed:12609047}.
UniProt	INDUCTION: By high-salt stress and abscisic acid (ABA) treatment. {ECO:0000269\|PubMed:11798174}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	BT138296	0.0	BT138296.1 Medicago truncatula clone JCVI-FLMt-3O7 unknown mRNA.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013441464.1	1e-144	dehydration-responsive element-binding protein 2A
Refseq	XP_024629841.1	1e-144	dehydration-responsive element-binding protein 2A
Refseq	XP_024629842.1	1e-144	dehydration-responsive element-binding protein 2A
Refseq	XP_024629844.1	1e-144	dehydration-responsive element-binding protein 2A
Refseq	XP_024629845.1	1e-144	dehydration-responsive element-binding protein 2A
Refseq	XP_024629846.1	1e-144	dehydration-responsive element-binding protein 2A
Swissprot	A2WL19	1e-49	DRE2A_ORYSI; Dehydration-responsive element-binding protein 2A
Swissprot	Q0JQF7	2e-49	DRE2A_ORYSJ; Dehydration-responsive element-binding protein 2A
Swissprot	Q8LFR2	3e-49	DRE2C_ARATH; Dehydration-responsive element-binding protein 2C
TrEMBL	A0A072TD68	1e-143	A0A072TD68_MEDTR; Dehydration-responsive element-binding protein
STRING	XP_004513549.1	1e-106	(Cicer arietinum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1175	34	106

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G05410.2	5e-43	DRE-binding protein 2A

Link Out ? help Back to Top
Phytozome	Medtr0939s0010.1
Entrez Gene	25481505

Publications ? help Back to Top
Kikuchi S, et al. Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice. Science, 2003. 301(5631): p. 376-9 [PMID:12869764] Sun SJ, et al. Functional analysis of a novel Cys2/His2-type zinc finger protein involved in salt tolerance in rice. J. Exp. Bot., 2010. 61(10): p. 2807-18 [PMID:20460361] Mallikarjuna G,Mallikarjuna K,Reddy MK,Kaul T Expression of OsDREB2A transcription factor confers enhanced dehydration and salt stress tolerance in rice (Oryza sativa L.). Biotechnol. Lett., 2011. 33(8): p. 1689-97 [PMID:21528404] Cui M, et al. Induced over-expression of the transcription factor OsDREB2A improves drought tolerance in rice. Plant Physiol. Biochem., 2011. 49(12): p. 1384-91 [PMID:22078375] Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Yang A,Dai X,Zhang WH A R2R3-type MYB gene, OsMYB2, is involved in salt, cold, and dehydration tolerance in rice. J. Exp. Bot., 2012. 63(7): p. 2541-56 [PMID:22301384] Li X, et al. LcSAIN1, a novel salt-induced gene from sheepgrass, confers salt stress tolerance in transgenic Arabidopsis and rice. Plant Cell Physiol., 2013. 54(7): p. 1172-85 [PMID:23695503] Schmidt R, et al. Salt-responsive ERF1 regulates reactive oxygen species-dependent signaling during the initial response to salt stress in rice. Plant Cell, 2013. 25(6): p. 2115-31 [PMID:23800963] Huang YC,Huang WL,Hong CY,Lur HS,Chang MC Comprehensive analysis of differentially expressed rice actin depolymerizing factor gene family and heterologous overexpression of OsADF3 confers Arabidopsis Thaliana drought tolerance. Rice (N Y), 2012. 5(1): p. 33 [PMID:24279948] Zhang XX, et al. OsDREB2A, a rice transcription factor, significantly affects salt tolerance in transgenic soybean. PLoS ONE, 2013. 8(12): p. e83011 [PMID:24376625] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Wang ST, et al. MicroRNA319 positively regulates cold tolerance by targeting OsPCF6 and OsTCP21 in rice (Oryza sativa L.). PLoS ONE, 2014. 9(3): p. e91357 [PMID:24667308] Ma T, et al. LcWRKY5: an unknown function gene from sheepgrass improves drought tolerance in transgenic Arabidopsis. Plant Cell Rep., 2014. 33(9): p. 1507-18 [PMID:24913125] Zhao J, et al. Global transcriptional profiling of a cold-tolerant rice variety under moderate cold stress reveals different cold stress response mechanisms. Physiol Plant, 2015. 154(3): p. 381-94 [PMID:25263631] Chen M,Zhao Y,Zhuo C,Lu S,Guo Z Overexpression of a NF-YC transcription factor from bermudagrass confers tolerance to drought and salinity in transgenic rice. Plant Biotechnol. J., 2015. 13(4): p. 482-91 [PMID:25283804] Gao Y, et al. A maize phytochrome-interacting factor 3 improves drought and salt stress tolerance in rice. Plant Mol. Biol., 2015. 87(4-5): p. 413-28 [PMID:25636202] Sazegari S,Niazi A,Ahmadi FS A study on the regulatory network with promoter analysis for Arabidopsis DREB-genes. Bioinformation, 2015. 11(2): p. 101-6 [PMID:25848171] Cai W, et al. Overexpression of Rat Neurons Nitric Oxide Synthase in Rice Enhances Drought and Salt Tolerance. PLoS ONE, 2015. 10(6): p. e0131599 [PMID:26121399] Sakuraba Y, et al. Rice ONAC106 Inhibits Leaf Senescence and Increases Salt Tolerance and Tiller Angle. Plant Cell Physiol., 2015. 56(12): p. 2325-39 [PMID:26443376] Sato H, et al. The Arabidopsis transcriptional regulator DPB3-1 enhances heat stress tolerance without growth retardation in rice. Plant Biotechnol. J., 2016. 14(8): p. 1756-67 [PMID:26841113] Yu Y, et al. Transgenic rice expressing a cassava (Manihot esculenta Crantz) plasma membrane gene MePMP3-2 exhibits enhanced tolerance to salt and drought stresses. Genet. Mol. Res., 2016. [PMID:26909954] Huang KC,Lin WC,Cheng WH Salt hypersensitive mutant 9, a nucleolar APUM23 protein, is essential for salt sensitivity in association with the ABA signaling pathway in Arabidopsis. BMC Plant Biol., 2018. 18(1): p. 40 [PMID:29490615] Song C,Lee J,Kim T,Hong JC,Lim CO VOZ1, a transcriptional repressor of DREB2C, mediates heat stress responses in Arabidopsis. Planta, 2018. 247(6): p. 1439-1448 [PMID:29536220]