PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Medtr0022s0430.2

Common Name

MTR_0022s0430

Organism

Medicago truncatula

Taxonomic ID

3880

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Trifolieae; Medicago

Family

Nin-like

Protein Properties

Length: 743aa MW: 82811.3 Da PI: 6.0672

Description

Nin-like family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Medtr0022s0430.2	genome	Mt	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	RWP-RK	93.1	2e-29	455	506	1	52
RWP-RK 1 aekeisledlskyFslpikdAAkeLgvclTvLKriCRqyGIkRWPhRkiksl 52 aek+isle+l+ yFs+++kdAAk+Lgvc+T++KriCRq+GI+RWP+Rkik++ Medtr0022s0430.2 455 AEKSISLEVLQDYFSGSLKDAAKSLGVCPTTMKRICRQHGISRWPSRKIKKV 506 589***********************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51519	17.291	445	526	IPR003035	RWP-RK domain
Pfam	PF02042	4.8E-26	459	506	IPR003035	RWP-RK domain
SuperFamily	SSF54277	1.05E-23	645	732	No hit	No description
SMART	SM00666	2.1E-24	647	729	IPR000270	PB1 domain
PROSITE profile	PS51745	21.718	647	729	IPR000270	PB1 domain
Pfam	PF00564	2.8E-18	648	728	IPR000270	PB1 domain
Gene3D	G3DSA:3.10.20.240	1.1E-25	648	728	No hit	No description
CDD	cd06407	2.78E-34	648	728	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0005515	Molecular Function	protein binding

Sequence ? help Back to Top
Protein Sequence Length: 743 aa Download sequence Send to blast
MTQALRNFKE LTELNVLAQV WAPVRNGSRY KLTTSGQPFV LDAHSNGLHQ YRTVSLMYMF 60 SVDGENDEVL GLPGRVFQQK LPEWTPNVQY YSSKEYSRLN HALHYNVRGT LALPVFEPPG 120 QSCVAVLELI MTSQKINYAP EVDKVCKALE AVNLRSSEIL EHPYSQICNE DRQNALSEIL 180 EILTVVCETH NLPLAQTWVP CRHRSVLAHG GGLKKNCSSF DGYCMGQVCM SITEVAFYII 240 DSHTWGFHDA CVEHHLQQGQ GVAGRAFLSQ NMCFCRNITQ FCKTDYPLVH YALMFDLTSS 300 FSICLQSSHT GGDDYVLEFF LPPSINKFCE QKGLLGSILA TMKQNFQSLK VASGVELEED 360 GSVEIVEIIN GTVHSRLESV PIIQSTKLSA RHDDASPDME EGVPLDQSRQ KIITNFDDIN 420 DIGNLDDYAG GSIDQIHSLK TETKKKPSLR KRGKAEKSIS LEVLQDYFSG SLKDAAKSLG 480 VCPTTMKRIC RQHGISRWPS RKIKKVNRSL SKLKCVIESV HGVEGAFGLD SPSTSTIPIA 540 AGSFNEPSTS NKFEHHTSLS IMPSEPKKNE NYLDASKSEP QKPLGGMLIE GADSSKDLKN 600 LCPSTDVVLE DQVLEASRIH PPCSDFVHMQ MQHMDTLNFA AQKEMKIVTI KATYRDDIIR 660 FRVSWNCGIV ELREEIAKRL KLEVGTFDIK YLDDDQEWIL VACDADLQEC MDILTLSGSN 720 IIRLVVHDIL SILGSSVESS GE*

Sequence ? help Back to Top

Protein Sequence Length: 743 aa Download sequence Send to blast

MTQALRNFKE LTELNVLAQV WAPVRNGSRY KLTTSGQPFV LDAHSNGLHQ YRTVSLMYMF  60
SVDGENDEVL GLPGRVFQQK LPEWTPNVQY YSSKEYSRLN HALHYNVRGT LALPVFEPPG  120
QSCVAVLELI MTSQKINYAP EVDKVCKALE AVNLRSSEIL EHPYSQICNE DRQNALSEIL  180
EILTVVCETH NLPLAQTWVP CRHRSVLAHG GGLKKNCSSF DGYCMGQVCM SITEVAFYII  240
DSHTWGFHDA CVEHHLQQGQ GVAGRAFLSQ NMCFCRNITQ FCKTDYPLVH YALMFDLTSS  300
FSICLQSSHT GGDDYVLEFF LPPSINKFCE QKGLLGSILA TMKQNFQSLK VASGVELEED  360
GSVEIVEIIN GTVHSRLESV PIIQSTKLSA RHDDASPDME EGVPLDQSRQ KIITNFDDIN  420
DIGNLDDYAG GSIDQIHSLK TETKKKPSLR KRGKAEKSIS LEVLQDYFSG SLKDAAKSLG  480
VCPTTMKRIC RQHGISRWPS RKIKKVNRSL SKLKCVIESV HGVEGAFGLD SPSTSTIPIA  540
AGSFNEPSTS NKFEHHTSLS IMPSEPKKNE NYLDASKSEP QKPLGGMLIE GADSSKDLKN  600
LCPSTDVVLE DQVLEASRIH PPCSDFVHMQ MQHMDTLNFA AQKEMKIVTI KATYRDDIIR  660
FRVSWNCGIV ELREEIAKRL KLEVGTFDIK YLDDDQEWIL VACDADLQEC MDILTLSGSN  720
IIRLVVHDIL SILGSSVESS GE*

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, stems, leaves, flowers and siliques. Detected in root hairs, emerging secondary roots, vascular tissues, leaf parenchyma cells and stomata. {ECO:0000269\|PubMed:18826430}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in regulation of nitrate assimilation and in transduction of the nitrate signal. {ECO:0000269\|PubMed:18826430}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Medtr0022s0430.2

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Not regulated by the N source or by nitrate. {ECO:0000269\|PubMed:18826430}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_013443316.1	0.0	protein NLP7 isoform X2
Swissprot	Q84TH9	0.0	NLP7_ARATH; Protein NLP7
TrEMBL	A0A072TJH9	0.0	A0A072TJH9_MEDTR; Plant regulator RWP-RK family protein
STRING	GLYMA09G25230.2	0.0	(Glycine max)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G24020.1	0.0	NIN like protein 7

Link Out ? help Back to Top
Phytozome	Medtr0022s0430.2
Entrez Gene	25479714

Publications ? help Back to Top
Young ND, et al. The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature, 2011. 480(7378): p. 520-4 [PMID:22089132] Xu N, et al. The Arabidopsis NRG2 Protein Mediates Nitrate Signaling and Interacts with and Regulates Key Nitrate Regulators. Plant Cell, 2016. 28(2): p. 485-504 [PMID:26744214] Karve R,Suárez-Román F,Iyer-Pascuzzi AS The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release. Plant Physiol., 2016. 171(3): p. 2101-11 [PMID:27221617] Yu LH, et al. Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation. Sci Rep, 2016. 6: p. 27795 [PMID:27293103] Menz J,Li Z,Schulze WX,Ludewig U Early nitrogen-deprivation responses in Arabidopsis roots reveal distinct differences on transcriptome and (phospho-) proteome levels between nitrate and ammonium nutrition. Plant J., 2016. 88(5): p. 717-734 [PMID:27419465] Yan D, et al. NIN-like protein 8 is a master regulator of nitrate-promoted seed germination in Arabidopsis. Nat Commun, 2016. 7: p. 13179 [PMID:27731416] Guan P, et al. Interacting TCP and NLP transcription factors control plant responses to nitrate availability. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(9): p. 2419-2424 [PMID:28202720] Liu KH, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature, 2017. 545(7654): p. 311-316 [PMID:28489820] Li Z, et al. The Arabidopsis CPSF30-L gene plays an essential role in nitrate signaling and regulates the nitrate transceptor gene NRT1.1. New Phytol., 2017. 216(4): p. 1205-1222 [PMID:28850721] Cao H, et al. Overexpression of the Maize ZmNLP6 and ZmNLP8 Can Complement the Arabidopsis Nitrate Regulatory Mutant nlp7 by Restoring Nitrate Signaling and Assimilation. Front Plant Sci, 2017. 8: p. 1703 [PMID:29051766] Konishi N,Okubo T,Yamaya T,Hayakawa T,Minamisawa K Nitrate Supply-Dependent Shifts in Communities of Root-Associated Bacteria in Arabidopsis. Microbes Environ., 2017. 32(4): p. 314-323 [PMID:29187692] Karve RA,Iyer-Pascuzzi AS Further insights into the role of NIN-LIKE PROTEIN 7 (NLP7) in root cap cell release. Plant Signal Behav, 2018. 13(1): p. e1414122 [PMID:29215953] Zhao L, et al. The Arabidopsis NLP7 gene regulates nitrate signaling via NRT1.1-dependent pathway in the presence of ammonium. Sci Rep, 2018. 8(1): p. 1487 [PMID:29367694]