PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

XP_010102312.1

Organism

Morus notabilis

Taxonomic ID

981085

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus

Family

AP2

Protein Properties

Length: 573aa MW: 63158.9 Da PI: 6.6651

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
XP_010102312.1	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	35.5	2.5e-11	175	231	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + ++ k + g ++ +e+Aa+a++ a++k++g XP_010102312.1 175 SIYRGVTRHRWTGRYEAHLWDnSCR-RegQSrKGRQ-GGYDKEEKAARAYDLAALKYWG 231 57*****************5444.2455536655.779999************98 PP
2	AP2	29.3	2.1e-09	281	319	14	55
AP2 14 rWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 rW A+I + +k +lg+f t+eeAa+a++ a+ k++g XP_010102312.1 281 RWQARIGRVAG---NKDLYLGTFSTEEEAAEAYDIAAIKFRG 319 57777666422...5************************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	7.85E-15	175	241	IPR016177	DNA-binding domain
Pfam	PF00847	9.7E-9	175	231	IPR001471	AP2/ERF domain
CDD	cd00018	5.13E-20	175	241	No hit	No description
PROSITE profile	PS51032	17.504	176	239	IPR001471	AP2/ERF domain
SMART	SM00380	3.2E-23	176	245	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.6E-12	176	240	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-6	177	188	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	15.672	269	327	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.22E-14	274	328	IPR016177	DNA-binding domain
CDD	cd00018	3.12E-21	274	327	No hit	No description
SMART	SM00380	2.8E-24	275	333	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.4E-14	277	327	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.0E-6	309	329	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0000723	Biological Process	telomere maintenance
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0007389	Biological Process	pattern specification process
GO:0010073	Biological Process	meristem maintenance
GO:0010449	Biological Process	root meristem growth
GO:0019827	Biological Process	stem cell population maintenance
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 573 aa Download sequence Send to blast
MNSNNWLSFP LSPTHASLPP HLHSSQAHQF SLGLVNDNMD NMNPFQNQEW NLINSHGSSE 60 VPKVADFLGV SKSENQADLV AYNEIDQANH DSDYLFPNNM SLVPVVQQSS ALAAASSSAN 120 YDLQENPTNN LQSLTLSMGS SGKSSTCETS GDNSTNTVQE SVPRRTLDTF GQRTSIYRGV 180 TRHRWTGRYE AHLWDNSCRR EGQSRKGRQG GYDKEEKAAR AYDLAALKYW GTSTTTNFPI 240 SNYEKELEEM KHMTRQEFVA SIRRKSSGFS RGASMYRGVT RWQARIGRVA GNKDLYLGTF 300 STEEEAAEAY DIAAIKFRGL NAVTNFDMNR YDVKSILESN TLPIGGGAAK RLKEAQALES 360 SRKREEMMAL SSTFQYGSSS AASNRLQAAA YPLMQFDPHH HPTLLSLQNH HDSVSHYTSA 420 TQTTQDPSSF HQNYIQTQLQ LHQQQSGTTS YNNINHHHQQ ALGQSSSNNN SQTFYNGYNV 480 QNHPAFLQGL MDNINMGSAS NSIIDHNTNG GSTTATAGYN LGMPSNSTTT GNTAEELALV 540 KVDYDMTSGS GYGGWSGGSG QGSNPSVFTM WND

Sequence ? help Back to Top

Protein Sequence Length: 573 aa Download sequence Send to blast

MNSNNWLSFP LSPTHASLPP HLHSSQAHQF SLGLVNDNMD NMNPFQNQEW NLINSHGSSE  60
VPKVADFLGV SKSENQADLV AYNEIDQANH DSDYLFPNNM SLVPVVQQSS ALAAASSSAN  120
YDLQENPTNN LQSLTLSMGS SGKSSTCETS GDNSTNTVQE SVPRRTLDTF GQRTSIYRGV  180
TRHRWTGRYE AHLWDNSCRR EGQSRKGRQG GYDKEEKAAR AYDLAALKYW GTSTTTNFPI  240
SNYEKELEEM KHMTRQEFVA SIRRKSSGFS RGASMYRGVT RWQARIGRVA GNKDLYLGTF  300
STEEEAAEAY DIAAIKFRGL NAVTNFDMNR YDVKSILESN TLPIGGGAAK RLKEAQALES  360
SRKREEMMAL SSTFQYGSSS AASNRLQAAA YPLMQFDPHH HPTLLSLQNH HDSVSHYTSA  420
TQTTQDPSSF HQNYIQTQLQ LHQQQSGTTS YNNINHHHQQ ALGQSSSNNN SQTFYNGYNV  480
QNHPAFLQGL MDNINMGSAS NSIIDHNTNG GSTTATAGYN LGMPSNSTTT GNTAEELALV  540
KVDYDMTSGS GYGGWSGGSG QGSNPSVFTM WND

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269\|PubMed:15454085, ECO:0000269\|PubMed:15635403, ECO:0000269\|PubMed:16424342, ECO:0000269\|PubMed:20190735}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	XP_010102312.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin accumulation. {ECO:0000269\|PubMed:15454085}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KF543364	9e-88	KF543364.1 Rosa canina AP2 class putative transcription factor (PLT) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024453004.1	0.0	AP2-like ethylene-responsive transcription factor PLT1
Swissprot	Q5YGP7	0.0	PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2
TrEMBL	W9RQX4	0.0	W9RQX4_9ROSA; AP2-like ethylene-responsive transcription factor PLT2
STRING	XP_010102312.1	0.0	(Morus notabilis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4942	31	52

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G51190.1	0.0	AP2 family protein

Link Out ? help Back to Top
Entrez Gene	21398364

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Lee DK,Sieburth LE The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants. Plant Signal Behav, 2012. 7(6): p. 698-700 [PMID:22580686] Hong LW,Yan DW,Liu WC,Chen HG,Lu YT TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis. J. Exp. Bot., 2014. 65(1): p. 275-86 [PMID:24277277] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Zhao Q, et al. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche. J Integr Plant Biol, 2014. 56(12): p. 1151-63 [PMID:24831283] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Yang S, et al. The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance. Plant Cell, 2015. 27(6): p. 1670-80 [PMID:25991732] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Shinohara H,Mori A,Yasue N,Sumida K,Matsubayashi Y Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(14): p. 3897-902 [PMID:27001831] Ou Y, et al. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res., 2016. 26(6): p. 686-98 [PMID:27229312] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis . J Integr Plant Biol, 2017. 59(1): p. 30-43 [PMID:28074634] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]