PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010099679.1
Organism
Morus notabilis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family HD-ZIP
Protein Properties Length: 721aa    MW: 78895.6 Da    PI: 6.7794
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010099679.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox63.62.9e-202378156
                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
        Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                    +++ +++t++q++ Le++F+++++p++++r +L+++lgL  rq+k+WFqNrR+++k
  XP_010099679.1 23 KKRYHRHTAHQIQKLESMFKECPHPDEKQRLQLSRELGLAPRQIKFWFQNRRTQMK 78
                    678899***********************************************998 PP
2START1871e-582264502206
                     HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEE CS
           START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetl 82 
                     +a  a++el+++ + +ep+W ks+    + +n d +  +f++ ++       ++ea+r+ gvv+m+   lv  ++d++ +W e ++     a t+
  XP_010099679.1 226 IAANAMDELLRLLQTNEPLWIKSAvdgrDVLNLDNYEGIFPRPNShlknpnLRIEASRDAGVVIMNGLALVDMFMDSN-KWVELFPtivsMARTI 319
                     67889***********************9***********998889********************************.******9999999*** PP

                     EEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-E CS
           START  83 evissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehv 170
                     evissg      g+lqlm +elq+lsplvp R+f+f+Ry++q ++g w+ivdvS d +++++  ++  R+++lpSg+li++++ng+s+vtwvehv
  XP_010099679.1 320 EVISSGvlgshsGTLQLMHQELQVLSPLVPtREFYFLRYCQQIEQGLWAIVDVSYDLPRDNQ-FANQCRSHRLPSGCLIQDMPNGYSRVTWVEHV 413
                     *************************************************************9.8******************************* PP

                     E--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
           START 171 dlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                     + ++++p h l+r l++sgla+ga +w+atlqr ce+
  XP_010099679.1 414 EIEDKTPtHRLYRDLIHSGLAFGAGRWLATLQRMCER 450
                     ***********************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.9E-22874IPR009057Homeodomain-like
SuperFamilySSF466893.22E-201080IPR009057Homeodomain-like
PROSITE profilePS5007118.0742080IPR001356Homeobox domain
SMARTSM003892.3E-192184IPR001356Homeobox domain
CDDcd000864.27E-192281No hitNo description
PfamPF000467.5E-182378IPR001356Homeobox domain
PROSITE patternPS0002705578IPR017970Homeobox, conserved site
PROSITE profilePS5084853.125216453IPR002913START domain
SuperFamilySSF559615.33E-39217451No hitNo description
CDDcd088752.30E-120220449No hitNo description
SMARTSM002347.4E-51225450IPR002913START domain
PfamPF018521.0E-50226450IPR002913START domain
Gene3DG3DSA:3.30.530.203.6E-9322449IPR023393START-like domain
SuperFamilySSF559615.63E-24471647No hitNo description
SuperFamilySSF559615.63E-24674713No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 721 aa     Download sequence    Send to blast
MEYASGGSGG GRDNDASDAQ RRKKRYHRHT AHQIQKLESM FKECPHPDEK QRLQLSRELG  60
LAPRQIKFWF QNRRTQMKAQ HERADNCGLR AENDKIRCEN IAIREALKNV ICPSCGGPPI  120
NDDCFFDEQK LRMENAQLKE ELDRVSSIAA KYIGRPISQL PPVQPIHISS LDLSMASFGA  180
YHGLGGCGGG PSLDLDLLPG SSSSIPTMPY QPPGISDMDK SLMTDIAANA MDELLRLLQT  240
NEPLWIKSAV DGRDVLNLDN YEGIFPRPNS HLKNPNLRIE ASRDAGVVIM NGLALVDMFM  300
DSNKWVELFP TIVSMARTIE VISSGVLGSH SGTLQLMHQE LQVLSPLVPT REFYFLRYCQ  360
QIEQGLWAIV DVSYDLPRDN QFANQCRSHR LPSGCLIQDM PNGYSRVTWV EHVEIEDKTP  420
THRLYRDLIH SGLAFGAGRW LATLQRMCER FACLMVSGAS TRDLGGVIPS PDGKKSMMKL  480
AQRMVNNFCA SISTSNGHRW TTLSGLNEVG VRVTVHKSSD PGQPNGVVLS AATTIWLPIS  540
PQDVFNFFKD ERTRSQWDVL SNGNAVQEVA HIANGSHPGN CISVLRAFNT SQNNMLILQE  600
SSIDASGSVV VYCPVDLPAI NIAMSGEDPS YIPLLPSGFT ISPDGRTEPG GGGDGASTSS  660
AAVPPGNAMG RSSGSLITVA FQILVSSLPS AKLNLESVTT VNNLIGTTVQ QIKAALNCTN  720
S
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010099679.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010099679.10.0homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLW9RIV50.0W9RIV5_9ROSA; Homeobox-leucine zipper protein HDG11
STRINGXP_010099679.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]