PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID XP_010099050.1
Organism
Morus notabilis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Moraceae; Morus
Family ARF
Protein Properties Length: 937aa    MW: 104510 Da    PI: 7.8932
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
XP_010099050.1genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.71.1e-23240341199
                     EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSE CS
              B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrse 89 
                     f+k+lt sd++++g +++ +++a+e+      + + + +++l+ +d++g++W++++i+r++++r++l++GW+ Fv++++L +gD ++F   + ++
  XP_010099050.1 240 FCKTLTASDTSTHGGFSVLRRHADEClppldmSRQ-PPTQELVAKDLHGNEWRFRHIFRGQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGEN 331
                     99*****************************7333.34459************************************************..4499 PP

                     E..EEEEE-S CS
              B3  90 felvvkvfrk 99 
                     +el+v+v+r+
  XP_010099050.1 332 GELRVGVRRA 341
                     99*****996 PP
2Auxin_resp120.21.7e-39366448183
      Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                     a+ha+st+++F+v+Y+Pr+s++eF+v+++++++++k+++s+GmRfkm+fe+e+++e+r++Gt++gv+d+dp rW++SkWr+Lk
  XP_010099050.1 366 AWHAISTGTMFTVYYKPRTSPAEFIVPFDQYMESVKNNYSIGMRFKMKFEGEEAPEQRFTGTIIGVEDADPKRWTDSKWRCLK 448
                     89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.103.2E-42231355IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019364.71E-40237369IPR015300DNA-binding pseudobarrel domain
CDDcd100171.22E-21238340No hitNo description
PfamPF023621.3E-21240341IPR003340B3 DNA binding domain
PROSITE profilePS5086312.012240342IPR003340B3 DNA binding domain
SMARTSM010192.0E-23240342IPR003340B3 DNA binding domain
PfamPF065078.3E-37366448IPR010525Auxin response factor
PfamPF023091.0E-10797901IPR033389AUX/IAA domain
SuperFamilySSF542772.11E-11812889No hitNo description
PROSITE profilePS5174524.228812896IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009734Biological Processauxin-activated signaling pathway
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 937 aa     Download sequence    Send to blast
MVMVSTSEIS VKGNSGNPRG GERESFSSSG FADQNDGRKS AKGLSSTLFL RRQTPGEERE  60
RASLPPVSPT RTTVESPRKV CRRLFSSGAG KTIPAGFWSI FRRDFRVTEQ FRLFLSSDFV  120
SVCFVLVDAD DVALYKELWH ACAGPLVTVP RENERVFYFP QGHIEQVEAS TNQVAEQQMP  180
VYDLPSKILC RVMNVELKAE PDTDEVFAQI ILLPEQQQDE NAVEKGSPPP SPPRIQVHSF  240
CKTLTASDTS THGGFSVLRR HADECLPPLD MSRQPPTQEL VAKDLHGNEW RFRHIFRGQP  300
RRHLLQSGWS VFVSSKRLVA GDAFIFLRGE NGELRVGVRR AMRKQDNVPS SVISSHSMHL  360
GVLATAWHAI STGTMFTVYY KPRTSPAEFI VPFDQYMESV KNNYSIGMRF KMKFEGEEAP  420
EQRFTGTIIG VEDADPKRWT DSKWRCLKVR WDETSTIPRP DRVSPWKIEP ALAPPALNPL  480
PVPRSKRPRS NIVPLSPDSS VLTREGSLKV TVDPSLPSAF SRVLQGQEYS TLRGNFAESN  540
ELDAAEKSVM WPPSLDDEKI DVVSASSRRY RSENWVASGR HEPTYTDLLS GFGATVDSSR  600
GIGSPCTDQS VVPVNSMRKQ DQDGRFNLHS SPRSMLPLPS PLSLGLDTNL KGSVQSGTIS  660
YQAQGRYVGF DDYPILHGHR VEHPHGNWFM PPPSSPHLEN LAHSKELISK PVLGQKNEAV  720
KPKEGNCKLF GYSLIRAEPA VSHTSVVDKS TGQRNLVSSQ AQKFEFAQKS EQAGGSKSAD  780
NPVPMNDQEK PLQTSQQHFR EGQGKAQSGS TRSCTKVHKQ GIALGRSVDL TKFNKYDELV  840
AELDRLFEFG GELMAPKKNW LIVYTDDEGD MMLVGDDPWQ EFCCMVRKIF IYTREEVQKM  900
SPGTLNSHGE GNQVSVEVMD AKEKPQTLPL SSIPANC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-17713347018354Auxin response factor 1
4ldw_A1e-17713347018354Auxin response factor 1
4ldw_B1e-17713347018354Auxin response factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:15960614, ECO:0000269|PubMed:16176952, ECO:0000269|PubMed:16339187}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapXP_010099050.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024023134.10.0auxin response factor 2B isoform X1
RefseqXP_024023135.10.0auxin response factor 2B isoform X2
RefseqXP_024023136.10.0auxin response factor 2B isoform X3
SwissprotQ94JM30.0ARFB_ARATH; Auxin response factor 2
TrEMBLW9RH450.0W9RH45_9ROSA; Auxin response factor
STRINGXP_010099050.10.0(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF32813366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Chao WS,Doğramaci M,Foley ME,Horvath DP,Anderson JV
    Selection and validation of endogenous reference genes for qRT-PCR analysis in leafy spurge (Euphorbia esula).
    PLoS ONE, 2012. 7(8): p. e42839
    [PMID:22916167]
  2. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Lyons R, et al.
    Fusarium oxysporum triggers tissue-specific transcriptional reprogramming in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0121902
    [PMID:25849296]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Zhao S,Zhang ML,Ma TL,Wang Y
    Phosphorylation of ARF2 Relieves Its Repression of Transcription of the K+ Transporter Gene HAK5 in Response to Low Potassium Stress.
    Plant Cell, 2016. 28(12): p. 3005-3019
    [PMID:27895227]
  8. Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z
    ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis .
    J Integr Plant Biol, 2017. 59(1): p. 30-43
    [PMID:28074634]
  9. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  10. Sanz-Fernández M, et al.
    Screening Arabidopsis mutants in genes useful for phytoremediation.
    J. Hazard. Mater., 2017. 335: p. 143-151
    [PMID:28441590]
  11. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]
  12. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  13. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  14. Sarkar Das S, et al.
    Expression dynamics of miRNAs and their targets in seed germination conditions reveals miRNA-ta-siRNA crosstalk as regulator of seed germination.
    Sci Rep, 2018. 8(1): p. 1233
    [PMID:29352229]