PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.O00242.2.p
Common NameMIMGU_mgv1a002027mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family HD-ZIP
Protein Properties Length: 683aa    MW: 75569.5 Da    PI: 6.2358
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.O00242.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox43.74.7e-141391856
                      HHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
          Homeobox 18 lFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                      +F+++++p++++r  L+++lgL  rq+k+WFqNrR+++k
  Migut.O00242.2.p  1 MFKECPHPDEKTRNLLSRELGLHPRQIKFWFQNRRTQMK 39
                      69**********************************998 PP
2START169.52.2e-531864122206
                       HHHHHHHHHHHHHHHC-T.T-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EE CS
             START   2 laeeaaqelvkkalaeep.gWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....ka 79 
                       +a +a++el+++++++e+ +W kss    e++n +++ ++f++ +        ++ea+r+sgvv+m++  lv  ++d + +W e ++    +a
  Migut.O00242.2.p 186 IAASAMDELIRLVQSNEEhLWIKSSsdgrEMLNLETYERTFPRPNDhlknpnVRIEASRDSGVVIMNSLALVDMFMDAN-KWVELFPtivsRA 277
                       67899*********976538*****9***************887669999999**************************.******99999** PP

                       EEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEE CS
             START  80 etlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvt 165
                        t+evissg      ++lqlm+ elq+ls lvp R f+f+R+++q + g w+iv vS d++ + ++ ss+ ++++lpSg+li++++ng+sk+t
  Migut.O00242.2.p 278 RTIEVISSGmlgsqsSTLQLMYEELQVLSALVPtRQFYFLRFRQQIEPGLWAIVNVSYDVPHQESQLSSSCKSQRLPSGCLIQDMPNGYSKIT 370
                       ***************************************************************9999************************** PP

                       EEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
             START 166 wvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                       wveh +++++ p h l+r l++sgla+ga +w +tlqr ce+
  Migut.O00242.2.p 371 WVEHCEVEDKAPiHRLYRDLIQSGLAFGAERWISTLQRTCER 412
                       ****************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.605.1E-14146IPR009057Homeodomain-like
PROSITE profilePS5007114.268141IPR001356Homeobox domain
SMARTSM003892.8E-4145IPR001356Homeobox domain
SuperFamilySSF466891.92E-12146IPR009057Homeodomain-like
PfamPF000461.7E-11139IPR001356Homeobox domain
CDDcd000869.24E-13242No hitNo description
PROSITE patternPS0002701639IPR017970Homeobox, conserved site
PROSITE profilePS5084845.407176415IPR002913START domain
SuperFamilySSF559618.24E-34177414No hitNo description
CDDcd088754.08E-113180411No hitNo description
SMARTSM002347.1E-43185412IPR002913START domain
PfamPF018529.7E-46186412IPR002913START domain
SuperFamilySSF559612.26E-20434610No hitNo description
SuperFamilySSF559612.26E-20637669No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 683 aa     Download sequence    Send to blast
MFKECPHPDE KTRNLLSREL GLHPRQIKFW FQNRRTQMKA QHERSDNCAL RADNDKIRCE  60
NIAIREALKN IICPSCGGPP VTEDSYFDEQ KLRIENAQLK EELDRVSSIA AKYIGRPISQ  120
LPPVQPIHIS SLDLSMASFG GHGINAGPTL DLDLDLLPGS SSSVIPNLPF PSLSISDLDK  180
SLMSDIAASA MDELIRLVQS NEEHLWIKSS SDGREMLNLE TYERTFPRPN DHLKNPNVRI  240
EASRDSGVVI MNSLALVDMF MDANKWVELF PTIVSRARTI EVISSGMLGS QSSTLQLMYE  300
ELQVLSALVP TRQFYFLRFR QQIEPGLWAI VNVSYDVPHQ ESQLSSSCKS QRLPSGCLIQ  360
DMPNGYSKIT WVEHCEVEDK APIHRLYRDL IQSGLAFGAE RWISTLQRTC ERVAYLMVPG  420
NSSRDPGGGV IPSPEGKRSM TRLAQRMVSN FCSSINPSNG QQWTSVSGMN EFEVRATLHR  480
STDPAQPNAV VLSAAATIWL PIPPQSVFNF FRDERTRPQW DVLSNQNPVQ EVAHISNGSH  540
PGNCISILRA YNTSQNNMLI LQESCIDSSG SIVVHCPVDL PSINVAMSGE DPTFLPLLPS  600
GFTISPDGGP HQLHHGQYDV ASTSSNSTTV DRSSSSGSLV TVVFQILVSN SPSARMSPET  660
VNTVNNLIGN TVHQIKAALN CN*
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.O00242.2.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012855673.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A022Q3Q00.0A0A022Q3Q0_ERYGU; Uncharacterized protein
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]