PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.M01862.1.p
Common NameLOC105948831, MIMGU_mgv1a001449mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family ARF
Protein Properties Length: 819aa    MW: 90544.9 Da    PI: 6.7112
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.M01862.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B374.71.1e-23128229199
                       EEEE-..-HHHHTT-EE--HHH.HTT......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS CS
                B3   1 ffkvltpsdvlksgrlvlpkkfaeeh......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgr 87 
                       f+k+lt sd++++g +++p++ ae+       +++++  ++l+ +d+++++W++++i+r++++r++lt+GW+ Fv+a++L +gD+v+F   ++
  Migut.M01862.1.p 128 FCKTLTASDTSTHGGFSVPRRAAEKVfppldfSLQPPA-QELIARDLHNNEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVAGDSVLFI--WN 217
                       99*****************************9777666.49************************************************..88 PP

                       SEE..EEEEE-S CS
                B3  88 sefelvvkvfrk 99 
                       ++ +l+++++r+
  Migut.M01862.1.p 218 EKNQLFLGIRRA 229
                       89999****997 PP
2Auxin_resp121.18.1e-40254337183
        Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                       aahaa+t+s F+++YnPras+seFv++++k++ka++ ++vsvGmRf+m fete+ss rr++Gt++gvsd+d+vrWpnS+Wrs+k
  Migut.M01862.1.p 254 AAHAAATNSRFTIFYNPRASPSEFVIPLAKYVKAVYhTRVSVGMRFRMLFETEESSVRRYMGTITGVSDMDSVRWPNSHWRSVK 337
                       79*********************************9789******************************************985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.35E-47113257IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.105.0E-41120243IPR015300DNA-binding pseudobarrel domain
CDDcd100171.33E-21127223No hitNo description
SMARTSM010194.8E-24128230IPR003340B3 DNA binding domain
PROSITE profilePS5086312.534128230IPR003340B3 DNA binding domain
PfamPF023621.9E-22128229IPR003340B3 DNA binding domain
PfamPF065076.5E-35254337IPR010525Auxin response factor
SuperFamilySSF542775.56E-8677760No hitNo description
PROSITE profilePS5174523.2685769IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009734Biological Processauxin-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 819 aa     Download sequence    Send to blast
MKPTAALNQP SPEGGENNCL NSELWHACSG PLVSLPCIGS HVVYFPQGHS EQVAVSTNQE  60
VDAQIPNHPT LPPQLICQLH NVTMHADIET DEVYAQLTLQ PLSPQEQKEV SFLPADLGCS  120
SRQPTNYFCK TLTASDTSTH GGFSVPRRAA EKVFPPLDFS LQPPAQELIA RDLHNNEWKF  180
RHIFRGQPKR HLLTTGWSVF VSAKRLVAGD SVLFIWNEKN QLFLGIRRAN RPQTVMPSSV  240
LSSDSMHLGL LAAAAHAAAT NSRFTIFYNP RASPSEFVIP LAKYVKAVYH TRVSVGMRFR  300
MLFETEESSV RRYMGTITGV SDMDSVRWPN SHWRSVKVGW DESTAGEKQQ RVSLWEIEPL  360
TTFPMYPSPF PLRLKRPWPP PTGFTSFAGM KSDDMALNSH LMWLRGGDGF GGGGGMQSLG  420
QGMGVPPAWM QQQQQQPPFA AMQNNDVYQA MVDPTKQMLS SIMQHQHLMN QPSFLQSLPL  480
SSYQPQAAPP PQQQSHATNL LHQQMLHQNS YNNNVLQIHQ QNQLSSTPIQ HAFDSQLSPN  540
IKPVAGNINS PLHSLLGSVS QESGWPTKRV ALDPLLSGGM SPQANIAHDS VSLPPFPGRE  600
CLIEQESTDP QNHFLFGVNI DSSSSLLMQN SNEIDNASMG FASSSYMHSD YSMNPAVTTS  660
SGCIDESGFL LSSDNNAGNA NPPNRTFVKV YKSGSFGRSL DITKFSSYHE LRSELSKMFG  720
LEGQLEGPLR SGWQLVFVDR ENDVLLLGDD PWQEFVNSVW CIKILSPQEI QDMGKRGLEL  780
LNSVHNRQRS NGSCDSYGGQ QESRNISAGI PSVGTLHF*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1591435845388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.M01862.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012827521.10.0PREDICTED: auxin response factor 6 isoform X2
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A022PS380.0A0A022PS38_ERYGU; Auxin response factor
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA23682452
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30330.10.0auxin response factor 6
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]