PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.J00719.1.p
Common NameMIMGU_mgv1a006165mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family E2F/DP
Protein Properties Length: 455aa    MW: 50075.9 Da    PI: 4.8597
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.J00719.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.53.5e-26153218171
           E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                       r+++sL llt+kf++l++++e+g ++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Migut.J00719.1.p 153 RYDSSLSLLTKKFITLIKHAEDGDLDLNKAADTL---QV--QKRRIYDITNVLEGIGLIEKKLKNRIHWKG 218
                       6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-27150220IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.36E-16153216IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.7E-33153218IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023194.7E-24155218IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440742.46E-33232335No hitNo description
PfamPF164212.7E-33234333IPR032198E2F transcription factor, CC-MB domain
CDDcd146604.55E-47234335No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 455 aa     Download sequence    Send to blast
MAGRGAPNRG SAAAATPPAS SGQILHQQQT PPASIRRHLP FASMKPPFVS SDDYHRFSTP  60
ARAAAAASSA DHAPEAIVVK SPRKNGYQNN DVESSEWAAS PGYNNIPNSP LCTPVAKGGR  120
SRSRVTKNNK SLPSTPISNV DAPSPLTPAG SCRYDSSLSL LTKKFITLIK HAEDGDLDLN  180
KAADTLQVQK RRIYDITNVL EGIGLIEKKL KNRIHWKGLD TSRPGEVDKD ATLLQAEIEN  240
LSMEETSLDD RIRQMQEKLR DLSEDENNQR LLFVTEDDIK NLPCFQNKTL IAVKAPHGTT  300
LEVPDPDEAV DYPQRRYRII LRSTMGPIDV YLVSQFEEKF EEMNGVVPEA ERPFLAHDAP  360
QNEAQNQESH EDSELGALQE NAGGMTRIVP SNIDNDADYW LLSNADVSMT DLWNRESIME  420
WNDVNLLPPE LELAAIGTPR SETPTSGIAD ITPR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-23148219274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00661PBMTransfer from Pp3c1_6880Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.J00719.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012828776.10.0PREDICTED: transcription factor E2FA
SwissprotQ9FNY01e-149E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A022PQX80.0A0A022PQX8_ERYGU; Uncharacterized protein
STRINGMigut.J00719.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA10772484
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-150E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]