PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.J00234.1.p
Common NameLOC105953027, MIMGU_mgv1a006676mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family C2H2
Protein Properties Length: 436aa    MW: 47527.9 Da    PI: 6.9308
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.J00234.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.00048122147123
                       EEET..TTTEEESSHHHHHHHHHH.T CS
           zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                       + C   +C ksF  ks+++ Hi+  H
  Migut.J00234.1.p 122 FICAapHCLKSFLKKSDFEWHINEtH 147
                       678888****************9988 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd001620.0060171105No hitNo description
PROSITE patternPS0051808796IPR017907Zinc finger, RING-type, conserved site
PROSITE profilePS501578.725122157IPR007087Zinc finger, C2H2
PROSITE patternPS000280124147IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 436 aa     Download sequence    Send to blast
MLQIRLSKPA NETGVSAKPA PTDSVTVACP DHLVLADLPV AKSLGSASAN AVIKTIGRRS  60
RRHLGERVHF CVRCDFPIAI YGRLSPCEHA FCLDCARSDS LCYLCDGRVQ KIQTIKMMEG  120
IFICAAPHCL KSFLKKSDFE WHINETHADL LHPGKEREGN ETEAISARKS SASDSTVQAP  180
LRQVFSPGSN SQVHEDKTQQ RPQTRDPQPP LRPVMQQTRP MPPFSGQAPN YPSEQQQQHT  240
DTNQPHNRFP QQTFDPQGQG GLRQESVNNP NSAMVPPQFG YPPYGGDGAQ QFFGAQYEMG  300
RTDSTPEAGS GQGSMSGFMP GPTGPVNFGQ NYPQQWNMAP TSLPMNVDPP QGANTDGFMN  360
VDPQGRGFYR GDYGQNVGPT PPTGNYMDTR DGKGILAPQP MSNPPPPQSA QIQRDRSYSG  420
DGNHDAPPGF GWQQD*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2mq1_A7e-1568147185E3 ubiquitin-protein ligase Hakai
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable E3 ubiquitin-protein ligase which is a subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs (PubMed:28503769). Associates with MTA, MTB, FIP37 and VIR to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences (PubMed:28503769). N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing (PubMed:28503769). {ECO:0000269|PubMed:28503769}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.J00234.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012832096.10.0PREDICTED: E3 ubiquitin-protein ligase Hakai isoform X1
SwissprotQ9LFC04e-98HAKAI_ARATH; E3 ubiquitin-protein ligase HAKAI homolog
TrEMBLA0A022RPV10.0A0A022RPV1_ERYGU; Uncharacterized protein
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA640445
Publications ? help Back to Top
  1. Růžička K, et al.
    Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI.
    New Phytol., 2017. 215(1): p. 157-172
    [PMID:28503769]