PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Migut.G00111.1.p

Common Name

LOC105948917, MIMGU_mgv1a002699mg

Organism

Mimulus guttatus

Taxonomic ID

4155

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe

Family

ARR-B

Protein Properties

Length: 647aa MW: 71901.4 Da PI: 6.2085

Description

ARR-B family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Migut.G00111.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	G2-like	90.9	1.1e-28	215	268	1	55
G2-like 1 kprlrWtpeLHerFveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 kpr++W+ eLH++Fv av++L G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl Migut.G00111.1.p 215 KPRVVWSVELHQQFVTAVNHL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 268 79*****************.******************************8 PP
2	Response_reg	78.7	2.1e-26	33	141	1	109
EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHH CS Response_reg 1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealk 91 vl+vdD+p+ +++l+++l++ y ev+++ +e al+ l++++ +D+++ D+ mp+mdG++ll++i e +lp+i+++a ++++ + + + Migut.G00111.1.p 33 VLVVDDDPTCLRILEKMLKNCLY-EVTTCNRAELALKFLRDNRngYDVVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDSKSVVMKGVT 123 89*******************.***********999999******************6654.8**************** PP TTESEEEESS--HHHHHH CS Response_reg 92 aGakdflsKpfdpeelvk 109 Ga d+l Kp+ +e+l + Migut.G00111.1.p 124 HGACDYLIKPVRMEALKN 141 ***********99986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PIRSF	PIRSF036392	9.2E-181	9	638	IPR017053	Response regulator B-type, plant
Gene3D	G3DSA:3.40.50.2300	2.0E-43	30	169	No hit	No description
SuperFamily	SSF52172	9.39E-36	30	156	IPR011006	CheY-like superfamily
SMART	SM00448	9.2E-31	31	143	IPR001789	Signal transduction response regulator, receiver domain
PROSITE profile	PS50110	42.62	32	147	IPR001789	Signal transduction response regulator, receiver domain
Pfam	PF00072	2.4E-23	33	141	IPR001789	Signal transduction response regulator, receiver domain
CDD	cd00156	8.00E-28	34	146	No hit	No description
SuperFamily	SSF46689	4.66E-20	212	272	IPR009057	Homeodomain-like
PROSITE profile	PS51294	10.667	212	271	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	5.9E-30	214	273	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	4.5E-25	215	268	IPR006447	Myb domain, plants
Pfam	PF00249	2.3E-7	217	267	IPR001005	SANT/Myb domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009414	Biological Process	response to water deprivation
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0010082	Biological Process	regulation of root meristem growth
GO:0010119	Biological Process	regulation of stomatal movement
GO:0010150	Biological Process	leaf senescence
GO:0010380	Biological Process	regulation of chlorophyll biosynthetic process
GO:0031537	Biological Process	regulation of anthocyanin metabolic process
GO:0080022	Biological Process	primary root development
GO:0080036	Biological Process	regulation of cytokinin-activated signaling pathway
GO:0080113	Biological Process	regulation of seed growth
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 647 aa Download sequence Send to blast
MDLGVKPMSY TSSNVSLKSG DGVSDMFPAG LRVLVVDDDP TCLRILEKML KNCLYEVTTC 60 NRAELALKFL RDNRNGYDVV ISDVHMPDMD GFKLLEHIGL EMDLPVIMMS ADDSKSVVMK 120 GVTHGACDYL IKPVRMEALK NIWQHVVRKK KYEFKDKDYE QSGSVDELDR QQKPNNNEDL 180 DYSSSANEGN WKNSKRRKEE EDEGDERDDS STLKKPRVVW SVELHQQFVT AVNHLGIDKA 240 VPKKILELMN VPGLTRENVA SHLQKYRLYL RRLSGVQHQN GLTNSFMGPS DMPFGQMSSL 300 NGVDFQALAA SGQLPPQSLA TIQAAALGRG PTKSSIPLPL VDQRNIFSFE NPKARFVESQ 360 SQSQTQQHIK QVNLLHGIPT NMDSKQLASL HQSAQSFNNM NMHNHVMQMS GQGQGQPQSR 420 SQILNEINVS DLPSSSSSSV ISQPVLSQAN IPTSFLGRNG IIASLPQPST VVDFSSQTTD 480 FAGSNNNINN NNNNNNSFSS KGSGEFVPSY DVFNDLYQNN RPQDWRVQNV QGGLDVSPSV 540 LVQQRFTTSN QKSVGQNRGL SVINNNINKT AYSEIGQQIN SSLSDNQLRI KAERLPDMGF 600 QNGIFPHEQH FGQEDLMSAF LKQQEGVGSV ENEFGFDGYH LDNLPV*

Sequence ? help Back to Top

Protein Sequence Length: 647 aa Download sequence Send to blast

MDLGVKPMSY TSSNVSLKSG DGVSDMFPAG LRVLVVDDDP TCLRILEKML KNCLYEVTTC  60
NRAELALKFL RDNRNGYDVV ISDVHMPDMD GFKLLEHIGL EMDLPVIMMS ADDSKSVVMK  120
GVTHGACDYL IKPVRMEALK NIWQHVVRKK KYEFKDKDYE QSGSVDELDR QQKPNNNEDL  180
DYSSSANEGN WKNSKRRKEE EDEGDERDDS STLKKPRVVW SVELHQQFVT AVNHLGIDKA  240
VPKKILELMN VPGLTRENVA SHLQKYRLYL RRLSGVQHQN GLTNSFMGPS DMPFGQMSSL  300
NGVDFQALAA SGQLPPQSLA TIQAAALGRG PTKSSIPLPL VDQRNIFSFE NPKARFVESQ  360
SQSQTQQHIK QVNLLHGIPT NMDSKQLASL HQSAQSFNNM NMHNHVMQMS GQGQGQPQSR  420
SQILNEINVS DLPSSSSSSV ISQPVLSQAN IPTSFLGRNG IIASLPQPST VVDFSSQTTD  480
FAGSNNNINN NNNNNNSFSS KGSGEFVPSY DVFNDLYQNN RPQDWRVQNV QGGLDVSPSV  540
LVQQRFTTSN QKSVGQNRGL SVINNNINKT AYSEIGQQIN SSLSDNQLRI KAERLPDMGF  600
QNGIFPHEQH FGQEDLMSAF LKQQEGVGSV ENEFGFDGYH LDNLPV*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1irz_A	2e-22	214	274	4	64	ARR10-B
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269\|PubMed:11370868, ECO:0000269\|PubMed:11574878, ECO:0000269\|PubMed:15282545, ECO:0000269\|PubMed:16407152}.
UniProt	Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Regulates SHY2 by binding to its promoter (PubMed:19039136). Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). {ECO:0000269\|PubMed:11574878, ECO:0000269\|PubMed:11691951, ECO:0000269\|PubMed:17363254, ECO:0000269\|PubMed:19039136}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00054	PBM	Transfer from AT4G16110	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Migut.G00111.1.p

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Down-regulated by gibberellin. {ECO:0000269\|PubMed:20605455}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012827641.1	0.0	PREDICTED: two-component response regulator ARR2 isoform X2
Swissprot	Q940D0	0.0	ARR1_ARATH; Two-component response regulator ARR1
Swissprot	Q9ZWJ9	0.0	ARR2_ARATH; Two-component response regulator ARR2
TrEMBL	A0A022RVC2	0.0	A0A022RVC2_ERYGU; Two-component response regulator

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3191	24	50

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G16857.1	1e-152	response regulator 1

Link Out ? help Back to Top
Phytozome	Migut.G00111.1.p
Entrez Gene	105948917

Publications ? help Back to Top
Bürkle L,Meyer S,Dortay H,Lehrach H,Heyl A In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system. Funct. Integr. Genomics, 2005. 5(3): p. 175-83 [PMID:15714319] Moubayidin L, et al. Spatial coordination between stem cell activity and cell differentiation in the root meristem. Dev. Cell, 2013. 26(4): p. 405-15 [PMID:23987513] Takahashi N, et al. Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots. Curr. Biol., 2013. 23(18): p. 1812-7 [PMID:24035544] Kurepa J,Li Y,Perry SE,Smalle JA Ectopic expression of the phosphomimic mutant version of Arabidopsis response regulator 1 promotes a constitutive cytokinin response phenotype. BMC Plant Biol., 2014. 14: p. 28 [PMID:24423196] Cortleven A, et al. A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors. Plant Physiol., 2014. 164(3): p. 1470-83 [PMID:24424319] Ge XM, et al. Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis. Plant J., 2015. 82(1): p. 138-50 [PMID:25704455] Takahashi N,Umeda M Cytokinins promote onset of endoreplication by controlling cell cycle machinery. Plant Signal Behav, 2014. 9(8): p. e29396 [PMID:25763620] Marín-de la Rosa N, et al. Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins. PLoS Genet., 2015. 11(7): p. e1005337 [PMID:26134422] D'Alessandro S,Golin S,Hardtke CS,Lo Schiavo F,Zottini M The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem. J. Exp. Bot., 2015. 66(16): p. 5113-22 [PMID:26163704] Jiang L, et al. Strigolactones spatially influence lateral root development through the cytokinin signaling network. J. Exp. Bot., 2016. 67(1): p. 379-89 [PMID:26519957] Moubayidin L, et al. A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis. Planta, 2016. 243(5): p. 1159-68 [PMID:26848984] Muraro D, et al. A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana. J. Theor. Biol., 2016. 404: p. 182-205 [PMID:27157127] Cortleven A, et al. Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes. Plant Physiol., 2016. 172(1): p. 464-78 [PMID:27388681] Kobayashi K, et al. Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling. Plant Physiol., 2017. 173(4): p. 2340-2355 [PMID:28193764] Arnaud D, et al. Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis. Plant Cell, 2017. 29(3): p. 543-559 [PMID:28254779] Zhang TQ, et al. A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration. Plant Cell, 2017. 29(5): p. 1073-1087 [PMID:28389585] Kushwah S,Laxmi A The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development. Plant Signal Behav, 2017. 12(5): p. e1312241 [PMID:28467152] Meng WJ, et al. Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL. Plant Cell, 2017. 29(6): p. 1357-1372 [PMID:28576846] Kobayashi K,Iwase A Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal. Plant Signal Behav, 2017. 12(6): p. e1338999 [PMID:28594268] Liu B,De Storme N,Geelen D Cold interferes with male meiotic cytokinesis in Arabidopsis thaliana independently of the AHK2/3-AHP2/3/5 cytokinin signaling module. Cell Biol. Int., 2017. 41(8): p. 879-889 [PMID:28618065] Zhang F,May A,Irish VF Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL. Trends Plant Sci., 2017. 22(10): p. 815-817 [PMID:28886911] Yan Z, et al. Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1. Plant Physiol., 2017. 175(3): p. 1438-1454 [PMID:28931628] Rong XF, et al. Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis. Plant Cell Physiol., 2018. 59(4): p. 756-764 [PMID:29186581] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938] Waldie T,Leyser O Cytokinin Targets Auxin Transport to Promote Shoot Branching. Plant Physiol., 2018. 177(2): p. 803-818 [PMID:29717021] Takatsuka H,Higaki T,Umeda M Actin Reorganization Triggers Rapid Cell Elongation in Roots. Plant Physiol., 2018. 178(3): p. 1130-1141 [PMID:30185441]