PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Migut.F00016.1.p
Common NameMIMGU_mgv1a003622mg
Organism
Mimulus guttatus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Phrymaceae; Erythranthe
Family bHLH
Protein Properties Length: 574aa    MW: 63508 Da    PI: 4.7602
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Migut.F00016.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH36.11.2e-11335377754
                       HHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS
               HLH   7 erErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 
                       ++ErrRR+++N+++  Lr+++Pk +      K++ a+iL  A++Y+k+L
  Migut.F00016.1.p 335 MAERRRRKKLNDRLYMLRSVVPKiS------KMDRASILGDAIDYLKEL 377
                       79*********************66......****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.866328377IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474592.36E-16331398IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.2E-14334383IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.8E-9334377IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000836.19E-13335381No hitNo description
Gene3DG3DSA:4.10.280.108.7E-16335392IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd048732.19E-7456497No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0016021Cellular Componentintegral component of membrane
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 574 aa     Download sequence    Send to blast
MLPPRSVWMD GEEEEEEEAA PMMISSSWNN NNNNEMDDAE MNMNMNASLS SFKSMLDNNP  60
VDSSSSSAAA AAAAFINNNG NASASPFYNI NNDFSTNHLY FNPPLDLDSS SSLSNPPFIL  120
DNHNQMPPNN KSLVIPSLFN NIFDNPFDFS SCDPPSFFPS LDPPPPPPPL FMGPAAAFDA  180
SLTSLFHPTP DFFPLPHDTT SAAPFFEGFD LTNRSKLLRP LQVSPPLGAP PTLFQKRAAL  240
RHTSKSDQGL TSLDDTVGME ELEWGKKRKR NYEDDDEDEM DDEMAAAADI STINYDSDEP  300
TDNKLGGDDN ANSSITVGAG LKGKKKGGMP AKNLMAERRR RKKLNDRLYM LRSVVPKISK  360
MDRASILGDA IDYLKELLQR INDLHNELEG TTPSSSSLGS MMQHQSTASF HPLTPTPPTL  420
PYRIVKEELC ASSTPSPKNQ PAKVEVRLRE GRGVNIHMFC ARRPGLLLST MRALDNLGLD  480
IQQAVISCFN GFALDVFRAE VRMFRPSRSK QCFWILPSFM VLCRIHSCSN NLPLPPPTLL  540
DDFGTLLIYI YANLVLLFLL LLINICEFSL LVL*
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1323342KKKGGMPAKNLMAERRRRKK
2336343ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapMigut.F00016.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012844058.10.0PREDICTED: transcription factor SCREAM2
SwissprotQ9LPW31e-106SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLA0A022QZA70.0A0A022QZA7_ERYGU; Uncharacterized protein
STRINGMigut.F00016.1.p0.0(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA27032452
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.15e-92bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  4. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  5. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  6. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]